Assuntos
Serviços de Assistência Domiciliar , Terapia Ultravioleta , Atitude do Pessoal de Saúde , Custos e Análise de Custo , França , Serviços de Assistência Domiciliar/economia , Serviços de Assistência Domiciliar/legislação & jurisprudência , Serviços de Assistência Domiciliar/estatística & dados numéricos , Hospitalização/economia , Humanos , Terapia PUVA/efeitos adversos , Terapia PUVA/economia , Terapia PUVA/instrumentação , Terapia PUVA/estatística & dados numéricos , Psoríase/tratamento farmacológico , Psoríase/radioterapia , Ensaios Clínicos Controlados Aleatórios como Assunto , Terapia Ultravioleta/efeitos adversos , Terapia Ultravioleta/economia , Terapia Ultravioleta/instrumentação , Terapia Ultravioleta/estatística & dados numéricosRESUMO
BACKGROUND: Bath PUVA has been shown to be an effective alternative treatment for psoriasis with fewer systemic side effects than oral methoxsalen (8-MOP). The cost of 8-MOP and the need for a bath unit have prevented wider use of this treatment. OBJECTIVE: We investigated the safety and efficacy of sheet bath PUVA by restricting the volume of the psoralen/bath water solution to 10 L with the aid of a polyethylene sheet. METHODS: Fifty-eight patients with chronic plaque-type psoriasis were treated with bath PUVA in a concentration of 0.5 mg of 8-MOP per liter of water. RESULTS: The group required a median of 17 baths (95% confidence interval [CI], 14-20) for clearance. Total UVA dose for the entire group was 26 J/cm2(95% CI, 18-47). CONCLUSION: Sheet bath PUVA is safe, efficient, and easy. This regimen can significantly reduce the amount of 8-MOP required, thereby resulting in a favorable cost/benefit ratio.