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1.
Br J Surg ; 108(3): 277-285, 2021 04 05.
Artigo em Inglês | MEDLINE | ID: mdl-33793734

RESUMO

BACKGROUND: The effect of immediate total-body CT (iTBCT) on health economic aspects in patients with severe trauma is an underreported issue. This study determined the cost-effectiveness of iTBCT compared with conventional radiological imaging with selective CT (standard work-up (STWU)) during the initial trauma evaluation. METHODS: In this multicentre RCT, adult patients with a high suspicion of severe injury were randomized in-hospital to iTBCT or STWU. Hospital healthcare costs were determined for the first 6 months after the injury. The probability of iTBCT being cost-effective was calculated for various levels of willingness-to-pay per extra patient alive. RESULTS: A total of 928 Dutch patients with complete clinical follow-up were included. Mean costs of hospital care were €25 809 (95 per cent bias-corrected and accelerated (bca) c.i. €22 617 to €29 137) for the iTBCT group and €26 155 (€23 050 to €29 344) for the STWU group, a difference per patient in favour of iTBCT of €346 (€4987 to €4328) (P = 0.876). Proportions of patients alive at 6 months were not different. The proportion of patients alive without serious morbidity was 61.6 per cent in the iTBCT group versus 66.7 per cent in the STWU group (difference -5.1 per cent; P = 0.104). The probability of iTBCT being cost-effective in keeping patients alive remained below 0.56 for the whole group, but was higher in patients with multiple trauma (0.8-0.9) and in those with traumatic brain injury (more than 0.9). CONCLUSION: Economically, from a hospital healthcare provider perspective, iTBCT should be the diagnostic strategy of first choice in patients with multiple trauma or traumatic brain injury.


Assuntos
Traumatismo Múltiplo/diagnóstico por imagem , Traumatismo Múltiplo/economia , Tomografia Computadorizada por Raios X/economia , Imagem Corporal Total/economia , Adulto , Lesões Encefálicas Traumáticas/diagnóstico por imagem , Lesões Encefálicas Traumáticas/economia , Lesões Encefálicas Traumáticas/mortalidade , Análise Custo-Benefício , Feminino , Custos Hospitalares , Humanos , Escala de Gravidade do Ferimento , Masculino , Pessoa de Meia-Idade , Traumatismo Múltiplo/mortalidade , Países Baixos/epidemiologia , Radiografia/economia , Suíça/epidemiologia
2.
Eur J Trauma Emerg Surg ; 47(1): 195-200, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-31485705

RESUMO

PURPOSE: The amount of studies performed regarding a link between socioeconomic status (SES) and fatal outcome after traumatic injury is limited. Most research is focused on work-related injuries without taking other important characteristics into account. The aim of this study is to examine the association between SES and outcome after traumatic injury. METHODS: The study involved polytrauma patients [Injury Severity Score (ISS) ≥ 16] admitted to the Amsterdam University Medical Center (location VUmc) and Northwest Clinics Alkmaar (level 1 trauma centers). The SES of every patient was based on their postal code and represented with a "status score". Univariate and multivariable analyses were performed to estimate the association between SES and mortality, length of stay at the hospital and length of stay at the Intensive Care Unit (ICU). Z-statistics were used to determine the difference between the expected and actual survival, based on Trauma Revised Injury Severity Score (TRISS) and PSNL15 (probability of survival based on the Dutch population). RESULTS: A total of 967 patients were included in this study. The lowest SES group was significantly associated with more penetrating injuries and a younger age (45 years versus 55 years). Additionally, severely injured patients with lower SES were noted to have a prolonged stay at the ICU. Furthermore, differences were found in the expected and observed survival, especially for the lower SES groups. CONCLUSION: Polytrauma patients with lower SES have more often penetrating injuries, are younger and have a longer stay at the ICU. No association was found between SES and length of hospital stay and neither between SES and mortality.


Assuntos
Traumatismo Múltiplo/mortalidade , Classe Social , Estudos Transversais , Feminino , Humanos , Escala de Gravidade do Ferimento , Masculino , Pessoa de Meia-Idade , Países Baixos/epidemiologia , Centros de Traumatologia
3.
J Trauma Acute Care Surg ; 90(1): 185-190, 2021 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-33021602

RESUMO

BACKGROUND: There have been no clinical studies to sufficiently reveal the interaction effect generated by combinations of injury regions of multiple injuries. We hypothesized that certain combinations of trauma regions might lead to increased risk of traumatic death and aimed to verify this hypothesis using a nationwide trauma registry in Japan. MATERIALS AND METHODS: This was a retrospective study of trauma patients registered in the Japan Trauma Data Bank between 2004 and 2017. We included patients who suffered blunt trauma with an Injury Severity Score of 16 or more. The trauma was classified into four regions (head, chest, abdomen, and extremities), and a multivariable logistic regression analysis was performed that included interaction terms derived from the combination of two regions as covariates. RESULTS: We included 78,280 trauma patients in this study. Among them, 16,100 (20.6%) patients were discharged to death. Multivariable logistic regression showed the odds ratio (OR) of in-hospital death compared with patients without injury of an Abbreviated Injury Scale score of 3 or more in each injured region as follows: head score, 2.31 (95% confidence interval [CI], 2.13-2.51); chest score, 2.28 (95% CI, 2.17-2.39); abdomen score, 1.68 (95% CI, 1.56-1.82); and extremities score, 1.84 (95% CI, 1.76-1.93), respectively. In addition, the ORs of the statistically significant interaction terms were as follows: head-chest 1.29 (95% CI, 1.13-1.48), chest-abdomen 0.77 (95% CI, 0.67-0.88), chest-extremities 1.95 (95% CI, 1.77-2.14), and abdomen-extremities 0.70 (95% CI, 0.62-0.79), respectively. CONCLUSION: In this population, among patients with multiple injuries, a combination of head-chest trauma and chest-extremities trauma was shown to increase the risk of traumatic death. LEVEL OF EVIDENCE: Prognostic, Level III.


Assuntos
Traumatismo Múltiplo/mortalidade , Escala Resumida de Ferimentos , Traumatismos Abdominais/complicações , Adulto , Idoso , Traumatismos do Braço/complicações , Traumatismos Craniocerebrais/complicações , Feminino , Mortalidade Hospitalar , Humanos , Japão/epidemiologia , Modelos Logísticos , Masculino , Pessoa de Meia-Idade , Traumatismo Múltiplo/patologia , Fatores de Risco , Traumatismos Torácicos/complicações
4.
Eur J Trauma Emerg Surg ; 46(4): 903-911, 2020 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-30535521

RESUMO

PURPOSE: The AIS scale is a measurement tool for single injuries. The ISS is considered the gold standard for determining the severity of injured patients, and the NISS was developed to improve the ISS with respect to loss of information, as well as to facilitate its calculation. The aim of this study was to analyse what injury severity measure, calculated according to the Abbreviated Injury Scale (AIS), 1998 and 2005 (update 2008) versions, performs better with mortality, cost and hospital length of stay healthcare indicators. METHODS: This cross-sectional observational study was carried out between February 1st 2012 and February 1st 2013. Inclusion criteria were injured patients due to external causes admitted to trauma service through the emergency department. Manual coding of all injuries was performed and ISS and NISS scores were calculated for both versions of the AIS scale. Severity was then compared to mortality (in-hospital and at 30 days), healthcare cost, and length of hospital stay. RESULTS: The index with the best predictive capability for in-hospital mortality was NISS 05 (AUC = 0.811). There was a significant increase in hospital stay and healthcare cost in the most severe patients in all indexes, except for ISS 05. CONCLUSIONS: NISS is found to be an index with higher predictive capability for in-hospital mortality and correlates better to length of hospital stay and healthcare cost.


Assuntos
Escala de Gravidade do Ferimento , Traumatismo Múltiplo/classificação , Escala Resumida de Ferimentos , Adulto , Idoso , Estudos Transversais , Feminino , Custos de Cuidados de Saúde , Mortalidade Hospitalar , Humanos , Tempo de Internação/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , Traumatismo Múltiplo/mortalidade , Valor Preditivo dos Testes , Espanha
5.
Eur J Trauma Emerg Surg ; 45(6): 951-957, 2019 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-31227849

RESUMO

PURPOSE: Blunt aortic injuries (BAI) have historically been considered an indication for emergent surgical intervention. Nevertheless, the observation that the outcome of the concomitant traumatic injuries has a major impact on prognosis and the rise of thoracic endovascular aortic repair (TEVAR) as an effective therapy for BAI have significantly changed in recent years the treatment algorithm of this condition. Our objective was to identify findings associated with the aortic injury which would be the best predictor of prognosis, with the objective of guiding the decision-making process for selecting the optimal timing of aortic repair. METHODS: We reviewed blunt aortic injuries from 3 Level I Trauma Centers from July 2008 to December 2016. We analyzed overall and BAI-related 30-day mortality in relation to: hemodynamics, timing of treatment, TEVAR vs open repair, and aortic injury grade as defined by the Society for Vascular Surgery. Based on computed tomographic angiography (CT scan) imaging, we selected the radiologic aortic findings most indicative of high mortality risk, which we defined as "Radiographic Severe Injury" (RSI): (1) total/partial aortic transection, (2) active contrast extravasation, or (3) the association of 2 of more of the following: contained contrast extravasation > 10 mm, periaortic hematoma, and/or mediastinal hematoma with thickness > 10 mm, or significant left pleural effusion. RESULTS: Of a total of 76 consecutive patients, 50 (66%) underwent immediate repair, 24 (31%) delayed aortic repair, and 2 (3%) died prior to repair. 58 patients (76%) had TEVAR, while 16 (24%) had open repair. Overall mortality was 18% and BAI-related mortality was 13%. In BAI-related mortalities, 70% of patients had RSI. Patients with high risk of overall mortality had hypotension and tachycardia (SBP < 100, HR ≥ 100), high ISS, and required vasopressors. Factors only associated with BAI-related mortality included RSI. CONCLUSION: CT scan findings suggestive of RSI are predictive of mortality associated with BAI. Radiologic assessment of the severity of the aortic injury with characterization for the presence of RSI may represent the key factors to determine the optimal timing of treatment of the aortic injury and guide the overall treatment strategy. LEVEL OF EVIDENCE: IV.


Assuntos
Aorta/lesões , Traumatismo Múltiplo/diagnóstico por imagem , Ferimentos não Penetrantes/diagnóstico por imagem , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Aorta/diagnóstico por imagem , Aorta/cirurgia , Tomada de Decisão Clínica , Procedimentos Endovasculares/métodos , Feminino , Humanos , Escala de Gravidade do Ferimento , Masculino , Pessoa de Meia-Idade , Traumatismo Múltiplo/mortalidade , Traumatismo Múltiplo/cirurgia , Traumatismo Múltiplo/terapia , Radiografia , Estudos Retrospectivos , Medição de Risco , Tomografia Computadorizada por Raios X , Centros de Traumatologia/estatística & dados numéricos , Ferimentos não Penetrantes/mortalidade , Ferimentos não Penetrantes/cirurgia , Ferimentos não Penetrantes/terapia , Adulto Jovem
6.
Khirurgiia (Mosk) ; (1): 41-46, 2018.
Artigo em Russo | MEDLINE | ID: mdl-29376956

RESUMO

AIM: To objectify timing of DCS stages implementation in advanced age patients through lethal outcome risk assessment. MATERIAL AND METHODS: 128 advanced age patients with polytrauma were enrolled. RESULTS: It was concluded that specialized prognosis scale for advanced age patients with polytrauma allowed to objectify the transition time between DCS stages that led to decrease of mortality by 10.6%.


Assuntos
Traumatismo Múltiplo , Administração dos Cuidados ao Paciente/métodos , Medição de Risco/métodos , Idoso , Feminino , Humanos , Masculino , Traumatismo Múltiplo/diagnóstico , Traumatismo Múltiplo/mortalidade , Avaliação de Resultados em Cuidados de Saúde , Prognóstico , Federação Russa , Índices de Gravidade do Trauma
7.
Rev Epidemiol Sante Publique ; 66(1): 43-52, 2018 Feb.
Artigo em Francês | MEDLINE | ID: mdl-29221606

RESUMO

BACKGROUND: Resource allocation to hospitals is highly dependent on appropriate case coding. For trauma victims, the major diagnosis-coding category (DCC) is multiple trauma (DCC26), which triggers higher funding. We hypothesized that DCC26 has limited capacity for appropriate identification of severe trauma victims. METHODS: We studied Injury Severity Score (ISS), Trauma Related Injury Severity Score (TRISS) and in-hospital mortality using data recorded in three level 1 trauma centers over a 2-year period. Patients were divided into two groups: DCC26 and non-DCC26. For non-DCC26 patients, two subgroups were identified: patients with severe head trauma and patients with spinal trauma. Clinical endpoints were mortality, ISS>15 and TRISS, IGS II. Use of hospital resources was estimated using funding and expenditures associated with each patient. RESULTS: During the study period, 2570 trauma victims were included in the analysis. These patients were 39±18 years old, with median ISS=14, and observed mortality=10 %. Group DCC26 had 811 (31 %) patients, group non-DCC26 1855 (69 %) patients. DCC26 coding identified a more severely injured group of patients. However, in the group non-DCC26, there was a high proportion of severe trauma (ISS>15: 35 %; TRISS<0.95: 9 %). CONCLUSION: DCC26 is not an appropriate coding for severe trauma patients. For these patients, expenditures will include intensive care and rare and costly resources. We propose to take into account the TRISS score to improve trauma coding.


Assuntos
Sistemas Computadorizados de Registros Médicos/normas , Traumatismo Múltiplo/classificação , Alocação de Recursos , Índices de Gravidade do Trauma , Ferimentos e Lesões/classificação , Adulto , Bases de Dados Factuais , Feminino , Recursos em Saúde , Custos Hospitalares , Mortalidade Hospitalar , Humanos , Classificação Internacional de Doenças/classificação , Classificação Internacional de Doenças/normas , Masculino , Pessoa de Meia-Idade , Traumatismo Múltiplo/diagnóstico , Traumatismo Múltiplo/economia , Traumatismo Múltiplo/mortalidade , Alocação de Recursos/economia , Alocação de Recursos/normas , Estudos Retrospectivos , Centros de Traumatologia/economia , Ferimentos e Lesões/diagnóstico , Ferimentos e Lesões/economia , Ferimentos e Lesões/mortalidade , Adulto Jovem
8.
J Korean Med Sci ; 32(7): 1187-1194, 2017 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-28581278

RESUMO

Recent evidence has demonstrated the survival benefits of helicopter transport for trauma patients. The purpose of this study was to evaluate the effectiveness of hospital-based helicopter emergency medical services (H-HEMS) in comparison with ground ambulance transport in improving mortality outcomes in patients with major trauma. Study participants were divided into 2 groups according to type of transport to the trauma center; that is, either via ground emergency medical services (GEMS) or via H-HEMS. The study was conducted from October 2013 to July 2015. Mortality outcomes in the H-HEMS group were compared with those in the GEMS group by using the Trauma and Injury Severity Score (TRISS) analysis. The number of participants finally included in the study was 312. Among these patients, 63 were adult major trauma patients transported via H-HEMS, and 47.6% were involved in traffic accidents. For interhospital transport, the Z and W statistics revealed significantly higher scores in the H-HEMS group than in the GEMS group (Z statistic, 2.02 vs. 1.16; P = 0.043 vs. 0.246; W statistic, 8.87 vs. 2.85), and 6.02 more patients could be saved per 100 patients when H-HEMS was used for transportation. TRISS analysis revealed that the use of H-HEMS for transporting adult major trauma patients was associated with significantly improved survival compared to the use of GEMS.


Assuntos
Resgate Aéreo/estatística & dados numéricos , Escala de Gravidade do Ferimento , Traumatismo Múltiplo/mortalidade , Centros de Traumatologia/estatística & dados numéricos , Adulto , Idoso , Resgate Aéreo/economia , Análise Custo-Benefício , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , República da Coreia , Taxa de Sobrevida
9.
Chin J Traumatol ; 20(2): 75-80, 2017 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-28363517

RESUMO

PURPOSE: To accurately assess the mechanism, type and severity of injury in Iranian multiple trauma patients of a trauma center. METHODS: Patients with multiple traumas referring to the emergency department of Hasheminejad University Hospital in Mashhad, Iran, entered this cross sectional study from March 2013 to December 2013. All the patients with injury severity score (ISS) > 9 were included in this study. Data analysis was performed by SPSS software (Version 11.5) and P values less than 0.05 were considered as significant differences. RESULTS: Among the 6306 hospitalized trauma patients during this period, 148 had ISS>9. The male female ratio was 80%. The mean age of the patients was (33.5 ± 19.3) years. And 71% of the patients were younger than 44 years old. There were 19 (13%) deaths from which 68.5% were older than 44 years old. The mean transfer time from the injury scene to hospital was (55 ± 26) minutes. The most frequent mechanisms of injury were motorcycle crashes and falling from height, which together included 66.2% of all the injuries. A total of 84% of hospital deaths occurred after the first 24 h of hospitalization. Head and neck were the most common body injured areas with a prevalence of 111 cases (75%). CONCLUSION: Motorcycle crashes have high frequency in Iran. Since most victims are young males, injury prevention strategies should be considered to reduce the burden of injuries.


Assuntos
Escala de Gravidade do Ferimento , Traumatismo Múltiplo/epidemiologia , Acidentes de Trânsito/estatística & dados numéricos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Criança , Pré-Escolar , Estudos Transversais , Feminino , Mortalidade Hospitalar , Humanos , Lactente , Masculino , Pessoa de Meia-Idade , Traumatismo Múltiplo/mortalidade , Centros de Traumatologia , Adulto Jovem
10.
BMC Public Health ; 16(1): 1202, 2016 11 29.
Artigo em Inglês | MEDLINE | ID: mdl-27899078

RESUMO

BACKGROUND: Road traffic fatalities (RTF) are among the top ten causes of deaths in the world. The risk factors for RTF fatal victims have been extensively characterized, but studies of household burden of RTF have been very few in number. Accordingly, this article investigates post-crash impacts on RTF victims' family members, including the adverse impacts of lost income, occupational disruption, unfavorable family dynamics, and residential relocation. METHODS: Survey data from 1291 RTF family members interviewed in Taiwan in 2012 provide the evidence of impact used in this article. Twelve variables related to the family member's socio-demographic background were used to predict the scope of the adverse impact of a fatal crash in regression models developed for this analysis. RESULTS: RTF victims' spouses with relatively low personal incomes and strong dependence upon the crash victims were found to be most likely to experience a marked decrease in post- crash quality of life. RTF victims' family members who lived with few other adult cohabitants and had more juvenile dependents and were emotionally dependent on the victims were found to be quite likely to experience post- crash setbacks in occupational stability. RTF victims' family members who were emotionally dependent on the victims were found to be more likely to experience major family life disruptions. The younger the RTF victims' family members, and the more years since the crash, the higher the likelihood of residential relocation taking place. CONCLUSIONS: The results noted help identify those RTF victims' families that will most likely be adversely affected by the crash. The true societal costs of RTF crashes should include the adversities suffered by the fatal crash victims' families. Social welfare policies, mental health support, and timely supplemental resources should be made available to those surviving families most at risk of major life disruptions.


Assuntos
Acidentes de Trânsito/estatística & dados numéricos , Efeitos Psicossociais da Doença , Características da Família , Traumatismo Múltiplo/epidemiologia , Recuperação de Função Fisiológica , Adulto , Idoso , Idoso de 80 Anos ou mais , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Traumatismo Múltiplo/mortalidade , Traumatismo Múltiplo/psicologia , Traumatismo Múltiplo/reabilitação , Fatores de Risco , Taiwan/epidemiologia , Adulto Jovem
11.
West J Emerg Med ; 17(3): 315-23, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27330664

RESUMO

INTRODUCTION: Accurate field triage of critically injured patients to trauma centers is vital for improving survival. We sought to estimate the national degree of undertriage of trauma patients who die in emergency departments (EDs) by evaluating the frequency and characteristics associated with triage to non-trauma centers. METHODS: This was a retrospective cross-sectional analysis of adult ED trauma deaths in the 2010 National Emergency Department Sample (NEDS). The primary outcome was appropriate triage to a trauma center (Level I, II or III) or undertriage to a non-trauma center. We subsequently focused on urban areas given improved access to trauma centers. We evaluated the associations of patient demographics, hospital region and mechanism of injury with triage to a trauma versus non-trauma center using multivariable logistic regression. RESULTS: We analyzed 3,971 included visits, representing 18,464 adult ED trauma-related deaths nationally. Of all trauma deaths, nearly half (44.5%, 95% CI [43.0-46.0]) of patients were triaged to non-trauma centers. In a subgroup analysis, over a third of urban ED visits (35.6%, 95% CI [34.1-37.1]) and most rural ED visits (86.4%, 95% CI [81.5-90.1]) were triaged to non-trauma centers. In urban EDs, female patients were less likely to be triaged to trauma centers versus non-trauma centers (adjusted odds ratio [OR] 0.83, 95% CI [0.70-0.99]). Highest median household income zip codes (≥$67,000) were less likely to be triaged to trauma centers than lowest median income ($1-40,999) (OR 0.54, 95% CI [0.43-0.69]). Compared to motor vehicle trauma, firearm trauma had similar odds of being triaged to a trauma center (OR 0.90, 95% CI [0.71-1.14]); however, falls were less likely to be triaged to a trauma center (OR 0.50, 95 %CI [0.38-0.66]). CONCLUSION: We found that nearly half of all trauma patients nationally and one-third of urban trauma patients, who died in the ED, were triaged to non-trauma centers, and thus undertriaged. Sex and other demographic disparities associated with this triage decision represent targeted opportunities to improve our trauma systems and reduce undertriage.


Assuntos
Serviço Hospitalar de Emergência , Traumatismo Múltiplo/mortalidade , Triagem/estatística & dados numéricos , Ferimentos e Lesões/mortalidade , Adolescente , Adulto , Fatores Etários , Idoso , Estudos Transversais , Feminino , Pesquisa sobre Serviços de Saúde , Humanos , Escala de Gravidade do Ferimento , Cobertura do Seguro/estatística & dados numéricos , Masculino , Pessoa de Meia-Idade , Razão de Chances , Avaliação de Resultados em Cuidados de Saúde , Estudos Retrospectivos , Fatores Sexuais , Triagem/normas , Estados Unidos/epidemiologia , Ferimentos e Lesões/diagnóstico , Ferimentos e Lesões/terapia , Adulto Jovem
13.
J Orthop Trauma ; 30(6): 306-11, 2016 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-26741643

RESUMO

OBJECTIVES: We hypothesized that a standardized protocol for fracture care would enhance revenue by reducing complications and length of stay. DESIGN: Prospective consecutive series. SETTING: Level 1 trauma center. PATIENTS/PARTICIPANTS: Two hundread and fifty-three adult patients with a mean age of 40.7 years and mean Injury Severity Score of 26.0. INTERVENTION: Femur, pelvis, or spine fractures treated surgically. MAIN OUTCOME MEASUREMENTS: Hospital and professional charges and collections were analyzed. Fixation was defined as early (<36 hours) or delayed. Complications and hospital stay were recorded. RESULTS: Mean charges were US $180,145 with a mean of US $66,871 collected (37%). The revenue multiplier was US $59,882/$6989 (8.57), indicating hospital collection of US $8.57 for every professional dollar, less than half of which went to orthopaedic surgeons. Delayed fracture care was associated with more intensive care unit (4.5 vs. 9.4) and total hospital days (9.4 vs. 15.3), with mean loss of actual revenue US $6380/patient delayed (n = 47), because of the costs of longer length of stay. Complications were associated with the highest expenses: mean of US $291,846 charges and US $101,005 collections, with facility collections decreased by 5.1%. An uncomplicated course of care was associated with the most favorable total collections: (US $60,017/$158,454 = 38%) and the shortest mean stay (8.7 days). CONCLUSIONS: Facility collections were nearly 9 times more than professional collections. Delayed fixation was associated with more complications, and facility collections decreased 5% with a complication. Furthermore, delayed fixation was associated with longer hospital stay, accounting for US $300K more in actual costs during the study. A standardized protocol to expedite definitive fixation enhances the profitability of the trauma service line. LEVEL OF EVIDENCE: Economic Level IV. See Instructions for Authors for a complete description of levels of evidence.


Assuntos
Fraturas Ósseas/cirurgia , Custos Hospitalares , Tempo de Internação/economia , Traumatismo Múltiplo/economia , Ressuscitação/economia , Adulto , Idoso , Estudos de Coortes , Feminino , Fraturas do Fêmur/economia , Fraturas do Fêmur/cirurgia , Fixação de Fratura/economia , Fixação de Fratura/normas , Fraturas Ósseas/diagnóstico , Fraturas Ósseas/economia , Mortalidade Hospitalar/tendências , Humanos , Escala de Gravidade do Ferimento , Masculino , Pessoa de Meia-Idade , Traumatismo Múltiplo/diagnóstico , Traumatismo Múltiplo/mortalidade , Traumatismo Múltiplo/terapia , Ossos Pélvicos/lesões , Ossos Pélvicos/cirurgia , Estudos Prospectivos , Ressuscitação/mortalidade , Ressuscitação/normas , Fatores de Risco , Fraturas da Coluna Vertebral/economia , Fraturas da Coluna Vertebral/cirurgia , Centros de Traumatologia/economia
14.
Clin Lab ; 62(10): 2019-2024, 2016 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-28164531

RESUMO

BACKGROUND: One of the most severe conditions specific to the critically ill polytrauma patient is traumatic brain injury and traumatic spinal cord injury. The mortality rate is high in the case of these patients, both because of the direct traumatic lesions, and because of the pathophysiological imbalances associated with trauma. Amongst the most common pathologies associated with the critically ill polytrauma patients responsible for a lower survival rate, are redox imbalance, systemic inflammatory response, infections, and multiple organ dysfunction syndrome. METHODS: For this study, was analysed the literature available on PubMed. The key words used in the search were "traumatic brain injury", "spinal cord injury", "microRNAs expression", "polytrauma patients", and "biomarkers". RESULTS: For the study were selected 34 science articles. The oxidative attack on lipids is responsible for the biosynthesis of an increased quantity of free radicals, which further intensifies and aggravates the redox status in these patients. CONCLUSIONS: A new era for biomarkers is represented by the expression of miRNAs. In the case of the critically ill polytrauma patient, using miRNAs' expression as biomarkers for the evaluation and monitoring of the molecular and pathophysiological dysfunctions can bring a range of valuable answers that could contribute to an increased survival rate.


Assuntos
Lesões Encefálicas Traumáticas/genética , Estado Terminal , MicroRNAs/análise , Traumatismo Múltiplo/genética , Traumatismos da Medula Espinal/genética , Biomarcadores/análise , Lesões Encefálicas Traumáticas/mortalidade , Lesões Encefálicas Traumáticas/fisiopatologia , Humanos , Traumatismo Múltiplo/mortalidade , Traumatismo Múltiplo/fisiopatologia , Traumatismos da Medula Espinal/mortalidade , Traumatismos da Medula Espinal/fisiopatologia
15.
Adv Gerontol ; 29(5): 788-794, 2016.
Artigo em Russo | MEDLINE | ID: mdl-28556651

RESUMO

In this work the results of treatment of 116 patients with polytrauma older age groups was analysed, the comparison group consisted of 55 patients with multiple injuries aged 20 to 40 years. The objective of the study was the search of criteria of the objectification assess the severity of condition of patients of elderly and senile age with polytrauma on the basis of laboratory parameters and evaluation of the influence of concomitant somatic pathology on the level of lethality. We analysed the significance of each of the selected indicators and their entirety, thereby simplifying the formation of evidence-informed way to predict fatal outcome in patients of elderly and senile age with polytrauma.


Assuntos
Traumatismo Múltiplo , Idoso , Comorbidade , Estudos de Viabilidade , Feminino , Avaliação Geriátrica/métodos , Disparidades nos Níveis de Saúde , Humanos , Masculino , Traumatismo Múltiplo/diagnóstico , Traumatismo Múltiplo/epidemiologia , Traumatismo Múltiplo/mortalidade , Prognóstico , Federação Russa , Índices de Gravidade do Trauma
16.
J Bone Joint Surg Am ; 97(22): e73, 2015 Nov 18.
Artigo em Inglês | MEDLINE | ID: mdl-26582625

RESUMO

BACKGROUND: With the rise of obesity in the American population, there has been a proportionate increase of obesity in the trauma population. The purpose of this study was to use a computed tomography-based measurement of adiposity to determine if obesity is associated with an increased burden to the health-care system in patients with orthopaedic polytrauma. METHODS: A prospective comprehensive trauma database at a level-I trauma center was utilized to identify 301 patients with polytrauma who had orthopaedic injuries and intensive care unit admission from 2006 to 2011. Routine thoracoabdominal computed tomographic scans allowed for measurement of the truncal adiposity volume. The truncal three-dimensional reconstruction body mass index was calculated from the computed tomography-based volumes based on a previously validated algorithm. A truncal three-dimensional reconstruction body mass index of <30 kg/m(2) denoted non-obese patients and ≥ 30 kg/m(2) denoted obese patients. The need for orthopaedic surgical procedure, in-hospital mortality, length of stay, hospital charges, and discharge disposition were compared between the two groups. RESULTS: Of the 301 patients, 21.6% were classified as obese (truncal three-dimensional reconstruction body mass index of ≥ 30 kg/m(2)). Higher truncal three-dimensional reconstruction body mass index was associated with longer hospital length of stay (p = 0.02), more days spent in the intensive care unit (p = 0.03), more frequent discharge to a long-term care facility (p < 0.0002), higher rate of orthopaedic surgical intervention (p < 0.01), and increased total hospital charges (p < 0.001). CONCLUSIONS: Computed tomographic scans, routinely obtained at the time of admission, can be utilized to calculate truncal adiposity and to investigate the impact of obesity on patients with polytrauma. Obese patients were found to have higher total hospital charges, longer hospital stays, discharge to a continuing-care facility, and a higher rate of orthopaedic surgical intervention.


Assuntos
Fraturas Ósseas/terapia , Preços Hospitalares/estatística & dados numéricos , Luxações Articulares/terapia , Ligamentos/lesões , Traumatismo Múltiplo/terapia , Obesidade/complicações , Adiposidade , Adulto , Índice de Massa Corporal , Estudos de Casos e Controles , Feminino , Fraturas Ósseas/complicações , Fraturas Ósseas/economia , Fraturas Ósseas/mortalidade , Mortalidade Hospitalar , Humanos , Imageamento Tridimensional , Luxações Articulares/complicações , Luxações Articulares/economia , Luxações Articulares/mortalidade , Tempo de Internação/economia , Tempo de Internação/estatística & dados numéricos , Assistência de Longa Duração/estatística & dados numéricos , Extremidade Inferior/lesões , Masculino , Pessoa de Meia-Idade , Traumatismo Múltiplo/complicações , Traumatismo Múltiplo/economia , Traumatismo Múltiplo/mortalidade , Obesidade/diagnóstico por imagem , Obesidade/economia , Procedimentos Ortopédicos/economia , Procedimentos Ortopédicos/estatística & dados numéricos , Estudos Retrospectivos , Tomografia Computadorizada por Raios X , Centros de Traumatologia/economia , Centros de Traumatologia/estatística & dados numéricos , Estados Unidos
18.
Can J Surg ; 58(3 Suppl 3): S108-17, 2015 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-26100770

RESUMO

BACKGROUND: The initial nonoperative management (NOM) of blunt splenic injuries in hemodynamically stable patients is common. In soldiers who experience blunt splenic injuries with concomitant severe brain injury while on deployment, however, NOM may put the injured soldier at risk for secondary brain injury from prolonged hypotension. METHODS: We conducted a decision analysis using a Markov process to evaluate 2 strategies for managing hemodynamically stable patients with blunt splenic injuries and severe brain injury--immediate splenectomy and NOM--in the setting of a field hospital with surgical capability but no angiography capabilities. We considered the base case of a 40-year-old man with a life expectancy of 78 years who experienced blunt trauma resulting in a severe traumatic brain injury and an isolated splenic injury with an estimated failure rate of NOM of 19.6%. The primary outcome measured was life expectancy. We assumed that failure of NOM would occur in the setting of a prolonged casualty evacuation, where surgical capability was not present. RESULTS: Immediate splenectomy was the slightly more effective strategy, resulting in a very modest increase in overall survival compared with NOM. Immediate splenectomy yielded a survival benefit of only 0.4 years over NOM. CONCLUSION: In terms of overall survival, we would not recommend splenectomy unless the estimated failure rate of NOM exceeded 20%, which corresponds to an American Association for the Surgery of Trauma grade III splenic injury. For military patients for whom angiography may not be available at the field hospital and who require prolonged evacuation, immediate splenectomy should be considered for grade III-V injuries in the presence of severe brain injury.


CONTEXTE: La gestion non chirurgicale (GNC) initiale des traumatismes spléniques fermés chez les patients hémodynamiquement stables est fréquente. Toutefois, dans les cas de traumatismes spléniques fermés accompagnés de graves lésions cérébrales concomitantes durant leur déploiement, la GNC peut exposer les soldats blessés à un risque de lésion cérébrale secondaire par suite d'une hypotension prolongée. MÉTHODES: Nous avons appliqué un modèle de Markov à l'analyse décisionnelle pour évaluer 2 stratégies de prise en charge des patients hémodynamiquement stables porteurs de traumatismes spléniques fermés et de graves lésions cérébrales, soit la splénectomie immédiate et la GNC, dans le contexte d'un hôpital de campagne doté d'installations chirurgicales mais non d'installations angiographiques. Nous avons étudié le scénario de référence d'un homme de 40 ans ayant une espérance de vie de 78 ans, victime d'un traumatisme fermé entraînant une lésion cérébrale grave et un traumatisme splénique isolé, avec un taux estimé d'échec de la GNC de 19,6 %. Le principal paramètre mesuré était l'espérance de vie. Nous avons présumé que l'échec de la GNC surviendrait dans le contexte d'une évacuation prolongée des blessés en l'absence d'installations chirurgicales. RÉSULTANTS: La splénectomie immédiate s'est révélée être une stratégie légèrement plus efficace, entraînant une augmentation très modeste de la survie globale comparativement à la GNC. La splénectomie immédiate a produit un avantage de 0,4 an seulement au plan de la survie par rapport à la GNC. CONCLUSION: Au plan de la survie globale, nous ne recommanderions pas la splénectomie, à moins que le taux d'échec estimé de la GNC n'excède 20 %, ce qui correspond à un traumatisme splénique de grade III selon l'American Association for the Surgery of Trauma. Pour le personnel militaire blessé chez qui il est impossible de procéder à une angiographie dans un hôpital de campagne, et qui requiert une évacuation prolongée, il faut envisager une splénectomie immédiate pour les traumatisme de grade III V en présence de graves lésions cérébrales.


Assuntos
Lesões Encefálicas/terapia , Técnicas de Apoio para a Decisão , Militares , Traumatismo Múltiplo/terapia , Baço/lesões , Esplenectomia , Ferimentos não Penetrantes/terapia , Adulto , Lesões Encefálicas/mortalidade , Canadá , Humanos , Escala de Gravidade do Ferimento , Masculino , Cadeias de Markov , Traumatismo Múltiplo/mortalidade , Estudos Retrospectivos , Resultado do Tratamento , Ferimentos não Penetrantes/mortalidade
19.
Injury ; 45 Suppl 3: S53-8, 2014 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-25284235

RESUMO

BACKGROUND: Helicopter emergency medical service (HEMS) has been established in the preclinical treatment of multiple traumatised patients despite an ongoing controversy towards the potential benefit. Celebrating the 20th anniversary of TraumaRegister DGU(®) of the German Trauma Society (DGU) the presented study intended to provide an overview of HEMS rescue in Germany over the last 10 years analysing the potential beneficial impact of a nationwide helicopter rescue in multiple traumatised patients. PATIENTS AND METHODS: We analysed TraumaRegister DGU(®) including multiple traumatised patients (ISS ≥ 16) between 2002 and 2012. In-hospital mortality was defined as main outcome. An adjusted, multivariate regression with 13 confounders was performed to evaluate the potential survival benefit. RESULTS: 42,788 patients were included in the present study. 14,275 (33.4%) patients were rescued by HEMS and 28,513 (66.6%) by GEMS. Overall, 66.8% (n=28,569) patients were transported to a level I trauma centre and 28.2% (n=12,052) to a level II trauma centre. Patients rescued by HEMS sustained a higher injury severity compared to GEMS (ISS HEMS: 29.5 ± 12.6 vs. ISS GEMS: 27.5 ± 11.8). Helicopter rescue teams performed more on-scene interventions, and mission times were increased in HEMS rescue (HEMS: 77.2 ± 28.7 min. vs. GEMS: 60.9 ± 26.9 min.). Linear regression analysis revealed that the frequency of HEMS rescue has decreased significantly between 2002 and 2012. In case of transportation to level I trauma centres a decrease of 1.7% per year was noted (p<0.001) while a decline of 1.6% per year (p<0.001) was measured for level II trauma centre admissions. According to multivariate logistic regression HEMS was proven a positive independent survival predictor between 2002 and 2012 (OR 0.863; 95%-CI 0.800-0.930; Nagelkerkes-R(2) 0.539) with only little differences between each year. CONCLUSIONS: This study was able to prove an independent survival benefit of HEMS in multiple traumatised patients during the last 10 years. Despite this fact, a constant decline of HEMS rescue missions was found in multiple trauma patients due to unknown reasons. We concluded that HEMS should be used more often in case of trauma in order to guarantee the proven benefit for multiple traumatised patients.


Assuntos
Resgate Aéreo , Aeronaves , Serviços Médicos de Emergência , Centros de Traumatologia/organização & administração , Resgate Aéreo/economia , Resgate Aéreo/organização & administração , Análise Custo-Benefício , Serviços Médicos de Emergência/economia , Serviços Médicos de Emergência/organização & administração , Serviços Médicos de Emergência/tendências , Medicina de Emergência Baseada em Evidências , Feminino , Alemanha/epidemiologia , Necessidades e Demandas de Serviços de Saúde , Mortalidade Hospitalar , Humanos , Escala de Gravidade do Ferimento , Modelos Logísticos , Masculino , Traumatismo Múltiplo/mortalidade , Traumatismo Múltiplo/terapia , Análise de Sobrevida , Centros de Traumatologia/tendências
20.
Chirurg ; 85(3): 208, 210-4, 2014 Mar.
Artigo em Alemão | MEDLINE | ID: mdl-24519611

RESUMO

BACKGROUND: Multiple trauma is an independent injury pattern which, because of its complexity, is responsible for 25 % of the costs for the treatment of all injured patients. Because of the often long-lasting physical impairment and the high incidence of residual permanent handicaps, it is apparent that multiple trauma can lead to a reduction in patient quality of life. OBJECTIVES: The aim of this study was to give an overview of the known data concerning the change in quality of life for multiple trauma patients. Furthermore, predictors for the reduction of quality of life after multiple trauma will be identified. MATERIALS AND METHODS: A MedLine search was performed to identify studies dealing with the outcome after multiple trauma. RESULTS: In addition to functional outcome parameters, the term quality of life has become more important in recent years when it comes to evaluating the outcome following injury. While the mortality after multiple trauma could be significantly reduced over the years, there is no comparable effect on the quality of life. Predictors for a worse quality of life after multiple trauma are female gender, high age, low social status, concomitant head injuries and injury to the lower extremities. CONCLUSION: The fact that mortality after multiple trauma has decreased but not impairment of the quality of life makes it clear that in addition to the acute medical treatment, a follow-up treatment including not only physiotherapy but also psychotherapy is crucial for multiple trauma patients.


Assuntos
Traumatismo Múltiplo/psicologia , Traumatismo Múltiplo/cirurgia , Complicações Pós-Operatórias/psicologia , Qualidade de Vida/psicologia , Atividades Cotidianas/classificação , Atividades Cotidianas/psicologia , Lesões Encefálicas/economia , Lesões Encefálicas/mortalidade , Lesões Encefálicas/psicologia , Lesões Encefálicas/cirurgia , Análise Custo-Benefício/economia , Avaliação da Deficiência , Extremidades/lesões , Feminino , Alemanha , Custos de Cuidados de Saúde , Humanos , Masculino , Traumatismo Múltiplo/economia , Traumatismo Múltiplo/mortalidade , Programas Nacionais de Saúde/economia , Complicações Pós-Operatórias/economia , Complicações Pós-Operatórias/mortalidade , Pobreza/economia , Pobreza/psicologia , Fatores de Risco , Fatores Sexuais , Taxa de Sobrevida
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