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1.
Semin Perinatol ; 45(5): 151431, 2021 08.
Artigo em Inglês | MEDLINE | ID: mdl-33992443

RESUMO

We discuss the use of tele-mental health in settings serving expectant parents in fetal care centers and parents with children receiving treatment in neonatal intensive care units within a pediatric institution. Our emphasis is on the dramatic rise of tele-mental health service delivery for this population in the wake of the onset of the COVID-19 pandemic in the U.S., including relevant practice regulations, challenges and advantages associated with the transition to tele-mental health in these perinatal settings.


Assuntos
Atenção à Saúde , Unidades de Terapia Intensiva Neonatal/tendências , Saúde Mental/tendências , Assistência Perinatal , Intervenção Psicossocial , Telemedicina , COVID-19/epidemiologia , COVID-19/prevenção & controle , Atenção à Saúde/organização & administração , Atenção à Saúde/tendências , Feminino , Humanos , Controle de Infecções , Masculino , Pais/educação , Pais/psicologia , Assistência Perinatal/métodos , Assistência Perinatal/organização & administração , Gravidez , Educação Pré-Natal/tendências , Intervenção Psicossocial/métodos , Intervenção Psicossocial/tendências , SARS-CoV-2 , Telemedicina/métodos , Telemedicina/organização & administração , Estados Unidos/epidemiologia
2.
PLoS One ; 15(7): e0234866, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32645108

RESUMO

BACKGROUND: Traditional neonatal uvulectomy is unsupervised, unscientific and potentially dangerous cultural malpractice. It is often accompanied with life threatening neonatal morbidities such as infection, septicemia, anemia, aspiration and oropharyngeal injury. However, there is no current regional and even national data of its public health importance in the health care system. Therefore, this study was aimed at assessing the burden, associated factors and reasons of traditional uvulectomy among neonatal admissions at Debre Tabor General Hospital, North Central Ethiopia, from September 2018 to August 2019. METHODS: A quantitative cross sectional study supplemented with phenomenological study was employed on 422 mother-neonate pairs. Eight mothers who were not included in the quantitative part were involved as key informants of the qualitative study. Systematic and purposive sampling techniques were used to select study participants for the quantitative and qualitative parts of the study respectively. Multivariable logistic regressions were fitted to investigate significant predictors of traditional neonatal uvulectomy at p-value ≤ 0.05 and 95% CI. Moreover, the qualitative data were carefully transcribed, coded, screened, thematized, synthesized and then triangulated with the quantitative results. RESULTS: The burden of postuvulectomy admission was 67 (15.88%). Most of these admissions had post uvulectomy sepsis [59 (88.1%)] followed by anemia (55.23%). From multivariable analysis, factors that had significant odds of association with traditional neonatal uvulectomy include: having male neonate [AOR = 4.87; 95% CI: 1.10, 21.59], antenatal couple counseling about traditional neonatal uvulectomy [AOR = 0.053; 95% CI: 0.01, 0.35], home delivery [AOR = 6.02; 95% CI: 1.15, 31.61], postnatal couple counseling about traditional neonatal uvulectomy [AOR = 0.101; 95% CI: 0.02, 0.65], prior history of traditional neonatal uvulectomy [AOR = 7.15; 95% CI: 1.18, 43.21] and knowing at least one adverse effect of traditional neonatal uvulectomy [AOR = 0.068; 95% CI: 0.01, 0.44]. Furthermore, maternal perception of "there is no modern medicine to treat elongated and swollen neonatal uvula' was the most explained reason to practice traditional neonatal uvulectomy. CONCLUSION AND RECOMMENDATION: The burden of traditional neonatal uvulectomy was high. Fortunately, its predictors are modifiable. Therefore, several advocacy teams of neonatal health consisting of mainly women health development armies, elders, religious fathers, health professionals and criminal prosecutors should be actively mobilized against traditional neonatal uvulectomy. Besides, parental couple counseling about the adverse effects of traditional neonatal uvulectomy should be properly implemented in the routine antenatal and postnatal continuum of care in South Gondar Zone, North Central Ethiopia.


Assuntos
Mães/psicologia , Procedimentos Cirúrgicos Bucais/efeitos adversos , Úvula/cirurgia , Adulto , Comportamento Ritualístico , Estudos Transversais , Etiópia/epidemiologia , Feminino , Parto Domiciliar , Humanos , Lactente , Recém-Nascido , Unidades de Terapia Intensiva Neonatal/tendências , Masculino , Razão de Chances , Morte Perinatal/etiologia , Cuidado Pós-Natal , Gravidez
3.
JAMA Netw Open ; 3(6): e205239, 2020 06 01.
Artigo em Inglês | MEDLINE | ID: mdl-32556257

RESUMO

Importance: There are few population-based studies addressing trends in neonatal intensive care unit (NICU) admission and NICU patient-days, especially in the subpopulation that, by gestational age (GA) and birth weight (BW), might otherwise be able to stay in the room with their mothers. Objective: To describe population-based trends in NICU admissions, NICU patient-days, readmissions, and mortality in the birth population of a large integrated health care system. Design, Setting, and Participants: This cohort study was conducted using data extracted from electronic medical records at Kaiser Permanente Southern California (KPSC) health care system. Participants included all women who gave birth at KPSC hospitals and their newborns from January 1, 2010, through December 31, 2018. Data extraction was limited to data entry fields whose contents were either numbers or fixed categorical choices. Rates of NICU admission, NICU patient-days, readmission rates, and mortality rates were measured in the total population, in newborns with GA 35 weeks or greater and BW 2000 g or more (high GA and BW group), and in the remaining newborns (low GA and BW group). Admissions to the NICU and NICU patient-days were risk adjusted with a machine learning model based on demographic and clinical characteristics before NICU admission. Changes in the trends were assessed with 2-sided correlated seasonal Mann-Kendall test. Data analysis was performed in August 2019. Exposures: Admission to the NICU and NICU patient-days among the birth cohort. Main Outcomes and Measures: The primary outcomes were NICU admission and NICU patient-days in the total neonatal population and GA and BW subgroups. The secondary outcomes were readmission and mortality rates. Results: Over the study period there were 320 340 births (mean [SD] age of mothers, 30.1 [5.7] years; mean [SD] gestational age, 38.6 [1.97] weeks; mean [SD] birth weight, 3302 [573] g). The risk-adjusted NICU admission rate decreased from a mean of 14.5% (95% CI, 14.2%-14.7%) to 10.9% (95% CI, 10.7%-11.7%) (P for trend = .002); 92% of the change was associated with changes in the care of newborns in the high GA and BW group. The number of risk-adjusted NICU patient-days per birth decreased from a mean of 1.50 patient-days (95% CI, 1.43-1.54 patient-days) to 1.40 patient-days (95% CI, 1.36-1.48 patient-days) (P for trend = .03); 70% of the change was associated with newborns in the high GA and BW group. The unadjusted 30-day readmission rates and mortality rates did not change. Conclusions and Relevance: Admission rates to the NICU and numbers of NICU patient-days decreased over the study period without an increase in readmissions or mortality. The observed decrease was associated with the high GA and BW newborn population. How much of this decrease is attributable to intercurrent health care systemwide quality improvement initiatives would require further investigation. The remaining unexplained variation suggests that further changes are also possible.


Assuntos
Peso ao Nascer , Idade Gestacional , Unidades de Terapia Intensiva Neonatal/estatística & dados numéricos , Unidades de Terapia Intensiva Neonatal/tendências , Tempo de Internação/tendências , Admissão do Paciente/tendências , Adulto , Negro ou Afro-Americano/estatística & dados numéricos , California , Prestação Integrada de Cuidados de Saúde , Feminino , Humanos , Renda , Lactente , Mortalidade Infantil/tendências , Recém-Nascido de Baixo Peso , Recém-Nascido , Tempo de Internação/estatística & dados numéricos , Masculino , Idade Materna , Medicaid , Paridade , Admissão do Paciente/estatística & dados numéricos , Readmissão do Paciente/estatística & dados numéricos , Readmissão do Paciente/tendências , Gravidez , Gravidez Múltipla , Sistema de Registros , Estudos Retrospectivos , Fatores de Risco , Estados Unidos , Adulto Jovem
4.
Am Heart J ; 217: 121-130, 2019 11.
Artigo em Inglês | MEDLINE | ID: mdl-31654942

RESUMO

BACKGROUND: The risks and benefits of pharmacologic treatment and operative closure of patent ductus arteriosus (O-PDA) in premature infants remain controversial. Recent series have demonstrated the feasibility of transcatheter PDA closure (TC-PDA) in increasingly small infants. The effect of this change on practice has not been evaluated. METHODS: A multicenter observational study of infants treated in neonatal intensive care units in hospitals contributing data to the Pediatric Health Information Systems Database from January 2007 to December 2017 was performed to study trends in the propensities for (1) mechanical closure of PDA and (2) TC-PDA versus O-PDA, as well as interhospital variation in practice. RESULTS: A total of 6,214 subjects at 44 hospitals were studied (5% TC-PDA). Subject median gestational age was 25 weeks (interquartile range: 24-27 weeks). Median age at closure was 24 days (interquartile range: 14-36 days). The proportion of all neonatal intensive care unit patients undergoing either O-PDA or TC-PDA decreased (3.1% in 2007 and 0.7% in 2017, P < .001), whereas the proportion in which TC-PDA was used increased significantly (0.1% in 2007 to 29.0% in 2017). Case-mix-adjusted multivariable models similarly demonstrated increasing propensity to pursue TC-PDA (odds ratio [OR] 1.66 per year, P < .001) with acceleration of the trend after 2014 (OR 2.46 per year, P < .001) as well as significant practice variation (P < .001, median OR 4.6) across the study period. CONCLUSIONS: In the face of decreasing closure of PDA, the use of TC-PDA increased dramatically with significant practice variability. This demonstrates that there is equipoise for potential clinical trials.


Assuntos
Análise de Dados , Permeabilidade do Canal Arterial/cirurgia , Sistemas de Informação em Saúde/estatística & dados numéricos , Unidades de Terapia Intensiva Neonatal/tendências , Grupos Diagnósticos Relacionados , Feminino , Idade Gestacional , Humanos , Lactente , Recém-Nascido , Recém-Nascido Prematuro , Masculino , Análise Multivariada , Pontuação de Propensão
5.
Pediatrics ; 144(3)2019 09.
Artigo em Inglês | MEDLINE | ID: mdl-31405887

RESUMO

OBJECTIVES: To examine changes in care practices over time by race and ethnicity and whether the decrease in hospital mortality and severe morbidities has benefited infants of minority over infants of white mothers. METHODS: Infants 22 to 29 weeks' gestation born between January 2006 and December 2017 at a Vermont Oxford Network center in the United States were studied. We examined mortality and morbidity rate differences and 95% confidence intervals for African American and Hispanic versus white infants by birth year. We tested temporal differences in mortality and morbidity rates between white and African American or Hispanic infants using a likelihood ratio test on nested binomial regression models. RESULTS: Disparities for certain care practices such as antenatal corticosteroids and for some in-hospital outcomes have narrowed over time for minority infants. Compared with white infants, African American infants had a faster decline for mortality, hypothermia, necrotizing enterocolitis, and late-onset sepsis, whereas Hispanic infants had a faster decline for mortality, respiratory distress syndrome, and pneumothorax. Other morbidities showed a constant rate difference between African American and Hispanic versus white infants over time. Despite the improvements, outcomes including hypothermia, mortality, necrotizing enterocolitis, late-onset sepsis, and severe intraventricular hemorrhage remained elevated by the end of the study period, especially among African American infants. CONCLUSIONS: Racial and ethnic disparities in vital care practices and certain outcomes have decreased. That the quality deficit among minority infants occurred for several care practice measures and potentially modifiable outcomes suggests a critical role for quality improvement initiatives tailored for minority-serving hospitals.


Assuntos
Negro ou Afro-Americano/estatística & dados numéricos , Disparidades em Assistência à Saúde/etnologia , Hispânico ou Latino/estatística & dados numéricos , Mortalidade Infantil/etnologia , Lactente Extremamente Prematuro , Morbidade , Etnicidade , Feminino , Disparidades em Assistência à Saúde/tendências , Humanos , Lactente , Mortalidade Infantil/tendências , Unidades de Terapia Intensiva Neonatal/tendências , Gravidez , Complicações na Gravidez/epidemiologia , Porto Rico/epidemiologia , Fatores Raciais , Estudos Retrospectivos , Fatores de Tempo , Estados Unidos/epidemiologia , População Branca/etnologia
6.
PLoS Med ; 16(7): e1002860, 2019 07.
Artigo em Inglês | MEDLINE | ID: mdl-31335869

RESUMO

BACKGROUND: The Indian government supports both public- and private-sector provision of hospital care for neonates: neonatal intensive care is offered in public facilities alongside a rising number of private-for-profit providers. However, there are few published reports about mortality levels and care practices in these facilities. We aimed to assess care practices, causes of admission, and outcomes from neonatal intensive care units (NICUs) in public secondary and private tertiary hospitals and both public and private medical colleges enrolled in a quality improvement collaborative in Telangana and Andhra Pradesh-2 Indian states with a respective population of 35 and 50 million. METHODS AND FINDINGS: We conducted a cross-sectional study between 30 May and 26 August 2016 as part of a baseline evaluation in 52 consenting hospitals (26 public secondary hospitals, 5 public medical colleges, 15 private tertiary hospitals, and 6 private medical colleges) offering neonatal intensive care. We assessed the availability of staff and services, adherence to evidence-based practices at admission, and case fatality after admission to the NICU using a range of tools, including facility assessment, observations of admission, and abstraction of registers and telephone interviews after discharge. Our analysis is adjusted for clustering and weighted for caseload at the hospital level and presents findings stratified by type and ownership of hospitals. In total, the NICUs included just over 3,000 admissions per month. Staffing and infrastructure provision were largely according to government guidelines, except that only a mean of 1 but not the recommended 4 paediatricians were working in public secondary NICUs per 10 beds. On admission, all neonates admitted to private hospitals had auscultation (100%, 19 of 19 observations) but only 42% (95% confidence interval [CI] 25%-62%, p-value for difference is 0.361) in public secondary hospitals. The most common single cause of admission was preterm birth (25%) followed by jaundice (23%). Case-fatality rates at age 28 days after admission to a NICU were 4% (95% CI 2%-8%), 15% (9%-24%), 4% (2%-8%) and 2% (1%-5%) (Chi-squared p = 0.001) in public secondary hospitals, public medical colleges, private tertiary hospitals, and private medical colleges, respectively, according to facility registers. Case fatality according to postdischarge telephone interviews found rates of 12% (95% CI 7%-18%) for public secondary hospitals. Roughly 6% of admitted neonates were referred to another facility. Outcome data were missing for 27% and 8% of admissions to private tertiary hospitals and private medical colleges. Our study faced the limitation of missing data due to incomplete documentation. Further generalizability was limited due to the small sample size among private facilities. CONCLUSIONS: Our findings suggest differences in quality of neonatal intensive care and 28-day survival between the different types of hospitals, although comparison of outcomes is complicated by differences in the case mix and referral practices between hospitals. Uniform reporting of outcomes and risk factors across the private and public sectors is required to assess the benefits for the population of mixed-care provision.


Assuntos
Prestação Integrada de Cuidados de Saúde/tendências , Mortalidade Hospitalar/tendências , Hospitais Privados/tendências , Hospitais Públicos/tendências , Mortalidade Infantil/tendências , Unidades de Terapia Intensiva Neonatal/tendências , Terapia Intensiva Neonatal/tendências , Indicadores de Qualidade em Assistência à Saúde/tendências , Estudos Transversais , Fidelidade a Diretrizes/tendências , Disparidades em Assistência à Saúde/tendências , Humanos , Índia , Lactente , Admissão do Paciente/tendências , Admissão e Escalonamento de Pessoal/tendências , Guias de Prática Clínica como Assunto , Medição de Risco , Fatores de Risco , Fatores de Tempo , Resultado do Tratamento
7.
Mol Genet Genomic Med ; 7(7): e00796, 2019 07.
Artigo em Inglês | MEDLINE | ID: mdl-31192527

RESUMO

BACKGROUND: Exome/genome sequencing (ES/GS) have been recently used in neonatal and pediatric/cardiac intensive care units (NICU and PICU/CICU) to diagnose and care for acutely ill infants, but the effectiveness of targeted gene panels for these purposes remains unknown. METHODS: RapSeq, a newly developed panel targeting 4,503 disease-causing genes, was employed on selected patients in our NICU/PICU/CICU. Twenty trios were sequenced from October 2015 to March 2017. We assessed diagnostic yield, turnaround times, and clinical consequences. RESULTS: A diagnosis was made in 10/20 neonates (50%); eight had de novo variants (ASXL1, CHD, FBN1, KMT2D, FANCB, FLNA, PAX3), one was a compound heterozygote for CHAT, and one had a maternally inherited GNAS variant. Preliminary reports were generated by 9.6 days (mean); final reports after Sanger sequencing at 16.3 days (mean). In all positive infants, the diagnosis changed management. In a case with congenital myasthenia, diagnosis and treatment occurred at 17 days versus 7 months in a historical control. CONCLUSIONS: This study shows that a gene panel that includes the majority of known disease-causing genes can rapidly identify a diagnosis in a large number of tested infants. Due to simpler deployment and interpretation and lower costs, this approach might represent an alternative to ES/GS in the NICU/PICU/CICU.


Assuntos
Doença/genética , Diagnóstico Precoce , Testes Genéticos/métodos , Diagnóstico , Técnicas e Procedimentos Diagnósticos , Exoma , Feminino , Testes Genéticos/economia , Testes Genéticos/tendências , Humanos , Lactente , Recém-Nascido , Unidades de Terapia Intensiva Neonatal/tendências , Masculino , Sequenciamento do Exoma
8.
Br J Clin Pharmacol ; 84(6): 1313-1323, 2018 06.
Artigo em Inglês | MEDLINE | ID: mdl-29624207

RESUMO

AIMS: Evidence for drug use in newborns is sparse, which may cause large differences in drug prescriptions. We aimed to investigate the differences between neonatal intensive care units (NICUs) in the Netherlands in currently prescribed drugs. METHODS: This multicentre study included neonates admitted during 12 months to four different NICUs. Drugs were classified in accordance with the Anatomical Therapeutic Chemical (ATC) classification system and assessed for on/off-label status in relation to neonatal age. The treatment protocols for four common indications for drug use were compared: pain, intubation, convulsions and hypotension. RESULTS: A total of 1491 neonates (GA range 23+6 -42+2 weeks) were included with a total of 32 182 patient days, 181 different drugs and 10 895 prescriptions of which 23% was off-label in relation to neonatal age. Overall, anti-infective drugs were most frequently used with a total of 3161 prescriptions, of which 4% was off-label in relation to neonatal age. Nervous system drugs included 2500 prescriptions of which 31% was off-label in relation to neonatal age. Nervous system drugs, blood and blood forming organs, and cardiovascular drugs showed the largest differences between NICUs with ranges of 919-2278, 554-1465, and 238-952 total prescriptions per 1000 patients per ATC class, respectively. CONCLUSIONS: We showed that drug use varies widely in neonatal clinical practice. The drug classes with the highest proportion of off-label drugs in relation to neonatal age showed the largest differences between NICUs, i.e. cardiovascular and nervous system drugs. Drug research in neonates should receive high priority to guarantee safe and appropriate medicines and optimal treatment.


Assuntos
Disparidades em Assistência à Saúde/tendências , Unidades de Terapia Intensiva Neonatal/tendências , Terapia Intensiva Neonatal/tendências , Padrões de Prática Médica/tendências , Medicamentos sob Prescrição/uso terapêutico , Consenso , Tratamento Farmacológico/tendências , Pesquisas sobre Atenção à Saúde , Humanos , Recém-Nascido , Países Baixos , Uso Off-Label , Medicamentos sob Prescrição/efeitos adversos , Estudos Retrospectivos
9.
Rev. Pesqui. (Univ. Fed. Estado Rio J., Online) ; 9(3): 795-802, jul.-set. 2017. tab, graf
Artigo em Inglês, Português | LILACS, BDENF | ID: biblio-982961

RESUMO

Objective: To identify the prevalence of the actions recommended by the MC in practice care for preterm newborns and/or low birth weight, by the nursing staff of the intensive neonatal care which is state reference for the MC. Method: Quantitative descriptive research, conducted through by applying a structured questionnaire with 37 mid-level nursing professionals in the Neonatal Intensive Care Unit, from February to April 2014. Results: Welcoming, encouraging touch, breastfeeding and environmental control are the actions performed by the team, each having 97% of practical applicability, and actions less executed, the diaper in the lateral position (83%), and the bathroom wrapped in swaddling clothes (58%). Conclusion: This team performs the care of humanized actions as recommended by the MC, and understands the importance of care for the development of newborns. There is the need of permanent education process in service.


Objetivo: Identificar a prevalência das ações preconizadas pelo MC na prática de cuidados ao recém-nascido pré-termo e/ou baixo peso, pela equipe de enfermagem de uma unidade de terapia intensiva neonatal que é referência estadual para o MC. Método: Pesquisa descritiva quantitativa, realizada através da aplicação de um questionário estruturado com 37 profissionais de enfermagem de nível médio, em Unidade de Terapia Intensiva Neonatal, de fevereiro a abril de 2014. Resultados: O acolhimento, o incentivo ao toque, o aleitamento materno e o controle ambiental são as ações mais executadas pela equipe, apresentando cada uma 97% de aplicabilidade prática, e como ações menos executadas, a troca de fralda em decúbito lateral (83%), e o banho envolto em cueiros (58%). Conclusão: Esta equipe realiza as ações humanizadas de cuidado conforme preconizados pelo MC, e compreende a importância desses cuidados para o desenvolvimento infantil dos recém-nascidos. Existe necessidade de processo de educação permanente em serviço.


Objetivo: Identificar la prevalencia de las acciones recomendadas por el MC en los cuidados del recién nacido prematuro y/o bajo peso de nacimiento, por el equipo de enfermería de una unidad de terapia intensiva prenatal, referencia estatal para el MC. Método: Estudio descriptivo cuantitativo, llevado a cabo mediante la aplicación de un cuestionario estructurado con 37 profesionales de enfermería de nivel técnico, en una Unidad de Terapia Intensiva Neonatal, de febrero a abril del 2014. Resultados: La acogida, el incentivo al roce, la lactancia materna y el control ambiental son las acciones más empleadas por el equipo, presentando cada una de ellas el 97% de aplicabilidad práctica. Por otro lado, hay acciones menos ejecutadas, como el cambio de pañales en decúbito lateral (83%) y el baño envuelto en paños (58%). Conclusión: Este equipa realiza las acciones humanizadas del cuidado de acuerdo con las recomendaciones del MC y comprende la importancia de estos cuidados para el desarrollo infantil de los recién nacidos. Existe la necesidad del proceso de educación permanente en servicio.


Assuntos
Feminino , Humanos , Recém-Nascido , Adulto , Pessoa de Meia-Idade , Recém-Nascido Prematuro , Unidades de Terapia Intensiva Neonatal/tendências , Método Canguru/métodos , Método Canguru/tendências , Método Canguru , Equipe de Enfermagem/métodos , Nascimento Prematuro/enfermagem , Nascimento Prematuro/terapia , Brasil , Política de Saúde/tendências , Humanização da Assistência
10.
Semin Fetal Neonatal Med ; 22(4): 260-266, 2017 08.
Artigo em Inglês | MEDLINE | ID: mdl-28456514

RESUMO

Most neonatal deaths worldwide occur in low- and middle-income countries (LMICs). Respiratory distress is an important cause of neonatal morbidity and mortality. The epidemiology of respiratory distress among term neonates who constitute the vast majority of births is under reported. The scarcely available data from LMICs suggest an incidence of 1.2% to 7.2% among term live births and greater morbidity compared to that in high-income countries. Pneumonia and meconium aspiration syndrome are the predominant causes among outborn neonates, but next only to transient tachypnea among inborn neonates. Community management of neonatal sepsis/pneumonia using simplified antibiotic regimens when referral is not feasible, implementation of non-invasive ventilation, and innovative low-cost technologies to deliver respiratory therapy are important advances that have taken place in these settings. There is an urgent need to generate data on respiratory morbidities among term neonates so that the limited resources in these settings can be allocated judiciously.


Assuntos
Acessibilidade aos Serviços de Saúde , Síndrome de Aspiração de Mecônio/terapia , Pneumonia/terapia , Síndrome do Desconforto Respiratório do Recém-Nascido/terapia , Terapia Respiratória , Terapia Combinada/economia , Terapia Combinada/tendências , Efeitos Psicossociais da Doença , Países em Desenvolvimento , Custos de Cuidados de Saúde/tendências , Acessibilidade aos Serviços de Saúde/economia , Humanos , Recém-Nascido , Unidades de Terapia Intensiva Neonatal/economia , Unidades de Terapia Intensiva Neonatal/tendências , Síndrome de Aspiração de Mecônio/economia , Síndrome de Aspiração de Mecônio/mortalidade , Pneumonia/economia , Pneumonia/mortalidade , Síndrome do Desconforto Respiratório do Recém-Nascido/economia , Síndrome do Desconforto Respiratório do Recém-Nascido/mortalidade , Terapia Respiratória/economia , Terapia Respiratória/tendências
11.
J Opioid Manag ; 11(4): 305-12, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-26312957

RESUMO

OBJECTIVE: Neonatal intensive care unit (ICU) care involves use of opiates to treat postoperative, ventilated, or chronically ill infants. Opiates provide necessary analgesia and sedation, but the morbidities include prolonged neonatal abstinence syndrome (NAS) and extended length of stay for dose tapering. Our objective was to quantify trends in opiate exposure in a tertiary care NICU. The authors hypothesize that medical opiate exposure and resultant ICU-acquired NAS would increase over time. DESIGN: Retrospective cross-sectional cohort study. SETTING: Tertiary care NICU. PATIENTS: High-risk inborn infants admitted in fiscal years 2003-2004, 2007-2008, and 2010-2011. MAIN OUTCOME MEASURE: Average cumulative morphine exposure (all opiate doses converted to morphine equivalents) per time epoch was compared in cohorts of clinically similar infants. Linear regression was used to assess the primary outcome, assessing changes in opiate exposure over time. RESULTS: Sixty-three infants were included in the final analysis. The primary analysis assessing cumulative opiate exposure per infant showed an increase of 134 mg per time epoch (95% CI-12, 279 mg, p-value 0.071). There was a statistically significant increase in the percent of infants with a diagnosis of iatrogenic NAS, increasing from 9 to 35 to 50 percent (p-value 0.012).


Assuntos
Analgésicos Opioides/farmacologia , Doença Iatrogênica/prevenção & controle , Doenças do Recém-Nascido/tratamento farmacológico , Unidades de Terapia Intensiva Neonatal , Síndrome de Abstinência Neonatal , Transtornos Relacionados ao Uso de Opioides , Estudos Transversais , Relação Dose-Resposta a Droga , Feminino , Humanos , Recém-Nascido , Doenças do Recém-Nascido/classificação , Doenças do Recém-Nascido/epidemiologia , Unidades de Terapia Intensiva Neonatal/estatística & dados numéricos , Unidades de Terapia Intensiva Neonatal/tendências , Tempo de Internação/estatística & dados numéricos , Masculino , Conduta do Tratamento Medicamentoso/estatística & dados numéricos , Conduta do Tratamento Medicamentoso/tendências , Síndrome de Abstinência Neonatal/etiologia , Síndrome de Abstinência Neonatal/terapia , Transtornos Relacionados ao Uso de Opioides/epidemiologia , Transtornos Relacionados ao Uso de Opioides/etiologia , Transtornos Relacionados ao Uso de Opioides/prevenção & controle , Farmacoepidemiologia , Estudos Retrospectivos , Estados Unidos/epidemiologia
12.
Early Hum Dev ; 90(12): 863-7, 2014 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-25463833

RESUMO

BACKGROUND: Everyday care practices can facilitate or hinder parents' participation and involvement in neonatal care. AIMS: To evaluate trends in family-centered care practices in the Neonatal Intensive Care unit in Turku University Hospital. STUDY DESIGN AND SUBJECTS: In this retrospective study, the patient charts of very preterm infants were reviewed in 4 cohorts: 2001 to 2002 (n=72), 2006 to 2007 (n=69), 2009 to 2010 (n=76), and 2011 to 2012 (n=78). OUTCOME MEASURES: Care practices with parental involvement were evaluated: 1) thermoregulation; 2) nutrition and feeding; 3) the beginning and number of skin-to-skin care episodes. As safety measures, the length of stay and weight gain were recorded at discharge. RESULTS: The significant trends included: a decrease in gestational age at the end of incubator care (mean 33.4 [standard deviation (SD) 1.36] to 31.6 [SD 1.1], p<0.001) and at the beginning of breast-feeding (35.3 [SD 1.34] to 33.1 [SD 1.89], p<0.001), bottle feeding (from 34.1 [SD 1.04] to 33.3 [SD 1.51], p=0.003) and skin-to-skin care (from 32.8 [SD 1.99] to 29.9 [SD 2.34], p<0.001). The changes were most remarkable in the infants below 28 weeks. In addition, weight gain increased from 110 g to 159 g per week (p<0.001). CONCLUSIONS: The hospital care practices of very preterm infants developed during the study period support parental involvement. During the same time period, the weight gain of very preterm infants improved, significantly. These practices can serve as indicators of progressive trends in family centered care.


Assuntos
Recém-Nascido Prematuro/fisiologia , Unidades de Terapia Intensiva Neonatal/tendências , Pais , Regulação da Temperatura Corporal , Aleitamento Materno , Participação da Comunidade , Enfermagem Familiar/tendências , Feminino , Idade Gestacional , Humanos , Recém-Nascido , Tempo de Internação , Masculino , Estado Nutricional , Alta do Paciente , Estudos Retrospectivos , Resultado do Tratamento , Aumento de Peso
13.
Pediatrics ; 134(5): e1405-10, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-25311605

RESUMO

Resuscitation and life-support treatments for infants born at the "cusp of viability" continue to be subject to clinical and ethical debate. Reported positive outcomes for these infants led our Neonatal Program to critically review our historic practice of discouraging resuscitation of infants born at <24 weeks' gestational age. This practice change required a multifaceted, collaborative approach including neonatal, perinatal, and obstetric efforts. An exceptional experience was the formation of a dedicated working group that included invaluable input from parents who had lived the NICU experience. The inclusion of family members in the development of clinical policy was a novel experience for NICU staff, which we feel ultimately resulted in a more ethically sound approach to the care of these infants and their families. In this article, we explore our experience of the process of policy change, which although detailed and transparent was also complex and challenging in development and implementation.


Assuntos
Política de Saúde/legislação & jurisprudência , Recém-Nascido Prematuro/fisiologia , Unidades de Terapia Intensiva Neonatal/legislação & jurisprudência , Ordens quanto à Conduta (Ética Médica)/legislação & jurisprudência , Canadá/epidemiologia , Idade Gestacional , Política de Saúde/tendências , Humanos , Recém-Nascido , Unidades de Terapia Intensiva Neonatal/tendências
14.
Indian J Pediatr ; 81(11): 1198-204, 2014 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-24928106

RESUMO

The number of Neonatal Intensive Care Units (NICUs) and Special Care Newborn Units (SCNUs) in the country has increased exponentially. However, their current status of functioning is not known. A structured questionnaire survey of 70 NICUs spread across the country was conducted to assess their infrastructure, staffing, equipment, patient profile and their involvement in research and training. Majority of the units were well staffed and led by neonatologists trained in India and abroad. All had facilities for mechanical ventilation and were equipped with sophisticated imported equipment. Yet, availability of in-house blood gas and X-ray, microbiology facility, invasive blood pressure monitoring and support of ophthalmologist was not universal. More than half had published papers in scientific journals and were having recognized training programs in neonatology. Though tremendous progress is visible since the last surveys, the number of NICUs is still grossly insufficient. The current and future gap in trained manpower is however daunting, and intensive efforts for expanding the in-service training programs and innovative approaches to training are required. There is an urgent need to improve the quality of care by launching collaborative quality improvement programs and mandatory periodic accreditation managed by independent empowered organizations. The focus has to move forward from simply 'survival till discharge' to 'intact complete life survival'. Simultaneously, the NICU care has to stay available and affordable for the masses.


Assuntos
Necessidades e Demandas de Serviços de Saúde , Unidades de Terapia Intensiva Neonatal/organização & administração , Previsões , Humanos , Índia , Recém-Nascido , Unidades de Terapia Intensiva Neonatal/tendências , Inquéritos e Questionários
15.
J Health Econ ; 35: 162-78, 2014 May.
Artigo em Inglês | MEDLINE | ID: mdl-24709038

RESUMO

We estimate the degree of supplier-induced demand for newborn treatment by exploiting changes in reimbursement arising from the introduction of the partial prospective payment system (PPS) in Japan. Under the partial PPS, neonatal intensive care unit (NICU) utilization became relatively more profitable than other procedures, since it was excluded from prospective payments. We find that hospitals have responded to PPS adoption by increasing NICU utilization and by more frequently manipulating infants' reported birth weights which in large part determine their maximum allowable stay in the NICU. This induced demand substantially increases the reimbursements received by hospitals.


Assuntos
Economia Hospitalar/estatística & dados numéricos , Mau Uso de Serviços de Saúde/economia , Necessidades e Demandas de Serviços de Saúde/economia , Unidades de Terapia Intensiva Neonatal/economia , Sistema de Pagamento Prospectivo/economia , Peso ao Nascer , Economia Hospitalar/legislação & jurisprudência , Fraude/economia , Mau Uso de Serviços de Saúde/tendências , Necessidades e Demandas de Serviços de Saúde/tendências , Humanos , Recém-Nascido , Revisão da Utilização de Seguros , Unidades de Terapia Intensiva Neonatal/estatística & dados numéricos , Unidades de Terapia Intensiva Neonatal/tendências , Japão , Tempo de Internação/economia , Tempo de Internação/legislação & jurisprudência , Tempo de Internação/tendências , Sistema de Pagamento Prospectivo/legislação & jurisprudência , Sistema de Pagamento Prospectivo/tendências , Análise de Regressão
16.
Pediatr Ann ; 43(2): e50-5, 2014 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-24512162

RESUMO

Hospitals have, for centuries, maintained a central position in the health care system, providing care for critically ill patients. Despite being a cornerstone of health care delivery, we are witnessing the beginning of a major transformation in their function. There are several forces driving this transformation, including health care costs, shortage of health care professionals, volume of people with chronic diseases, consumerism, health care reform, and hospital errors. The neonatal intensive care unit (NICU) at Utah Valley Regional Medical Center in Provo, Utah, began an aggressive redesign/quality improvement effort in 1990. It became obvious that our care processes were designed for health care deliverers and not for the families. An ongoing revamp of our care delivery processes was undertaken using significant input from a parent focus meeting, parental interviews, and development of a parent-to-parent support group. As a result of this work, it became obvious we needed a new model to truly empower parents. The idea of "NICU is Home" was born. We elected to make a mind shift, not to focus on what families think, but rather on how they think. Web cams and other video apparatus have been used in a number of NICUs across the country. We decided our equipment requirements would need to include high-resolution cameras, full high-definition video recording, autofocus, audio microphones, automatic noise reduction, and automatic low-light correction. Our conferencing software needed to accommodate multiple users and have multiple-picture capabilities, low band width, and inexpensive technology. It was recognized that a single video camera feed was insufficient to adequately capture the desired amount of information. Verbal communication between parents and their babies' principal care providers is critical. Parents loved the idea of expanding the remote NICU web cam of their baby to a two-way physician-parent communication bedside monitor. Doctors at Utah Valley Regional Medical Center now have a mobile desk using a WiFi computer/camera/audio to communicate with the family in real-time or leave a recording.


Assuntos
Cuidado do Lactente/organização & administração , Unidades de Terapia Intensiva Neonatal/organização & administração , Neonatologia/organização & administração , Telemedicina/organização & administração , Grupos Focais , Necessidades e Demandas de Serviços de Saúde , Humanos , Recém-Nascido , Unidades de Terapia Intensiva Neonatal/tendências , Relações Pais-Filho , Relações Médico-Paciente , Telemedicina/tendências , Estados Unidos
18.
Early Hum Dev ; 87 Suppl 1: S31-3, 2011 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-21251768

RESUMO

Sepsis-related morbidity and mortality are major problems in NICU. Preterm neonates display clinical characteristics that make them prone to infections. Due to the high frequency of severe neurodevelopmental sequelae in survivors, the best possible strategy to manage sepsis in NICU is to prevent them. Hygiene, cohorting, stewardship on use of H2-blockers, steroids and broad-spectrum antibiotic are mandatory, as well as proper management of central venous accesses and surgical devices. In addition, clinical research offers the opportunity of adopting pharmacological preventative strategies such as use of palivizumab to prevent RSV infection, use of fluconazole to prevent fungal sepsis, use of probiotics and lactoferrin to enhance the innate immunity, and use of pagibaximab to prevent staphylococcal sepsis.


Assuntos
Doenças do Prematuro/prevenção & controle , Recém-Nascido Prematuro , Unidades de Terapia Intensiva Neonatal/tendências , Terapia Intensiva Neonatal/tendências , Sepse/prevenção & controle , Anti-Infecciosos/administração & dosagem , Anti-Infecciosos/uso terapêutico , Antibioticoprofilaxia/métodos , Antibioticoprofilaxia/tendências , Efeitos Psicossociais da Doença , Sistemas de Liberação de Medicamentos/métodos , Humanos , Recém-Nascido , Recém-Nascido Prematuro/fisiologia , Terapia Intensiva Neonatal/métodos , Sepse/congênito , Sepse/patologia
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