Cost of care for individuals with cystic fibrosis: a regression approach to determining the impact of recombinant human DNase.
Pharmacotherapy
; 19(10): 1159-66, 1999 Oct.
Article
em En
| MEDLINE
| ID: mdl-10512065
ABSTRACT
We estimated direct medical costs of care and important determinants of the costs in patients with cystic fibrosis (CF), including therapy with recombinant human DNase (rhDNase). Costs were estimated with resource use data from the Epidemiologic Study of Cystic Fibrosis. Ordinary least squares regression was used to determine the effect of clinical and demographic variables on individual cost of care. The estimated cost of caring for 303 patients in Alberta was $2,279,801 in 1996. The mean cost of care was $7524 (range $386-92,376)/patient. Regression results indicated that age and forced expiratory volume predicted had a negative association with costs. Being female, receiving rhDNase, and having Pseudomonas aeruginosa or Burkholderia cepacia were all associated with high costs. Our estimates indicated large interindividual variation in cost of care for patients with CF.
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Temas:
ECOS
/
Financiamentos_gastos
Bases de dados:
MEDLINE
Assunto principal:
Infecções por Pseudomonas
/
Infecções por Burkholderia
/
Fibrose Cística
/
Desoxirribonucleases
Tipo de estudo:
Diagnostic_studies
/
Health_economic_evaluation
/
Prognostic_studies
Limite:
Adult
/
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Pharmacotherapy
Ano de publicação:
1999
Tipo de documento:
Article
País de afiliação:
Canadá