Detection and follow up of exocrine pancreatic insufficiency in cystic fibrosis: a review.
Eur J Pediatr
; 159(8): 563-8, 2000 Aug.
Article
em En
| MEDLINE
| ID: mdl-10968231
ABSTRACT
UNLABELLED Pancreatic function testing is particularly difficult when the degree of remaining function has to be quantified. Detection of pancreatic insufficiency can suggest the diagnosis of cystic fibrosis (CF). It is, however, also important to follow the degree of pancreatic insufficiency in CF since its function can decline with age. Adaptation of pancreatic enzyme replacement therapy on residual function is necessary. Different tests with their advantages and disadvantages are critically reviewed in this article with respect to specificity, sensitivity, performance and cost-effectiveness. CONCLUSION:
Elastase-1 detection in faeces is probably the easiest test for the detection of pancreatic insufficiency in cystic fibrosis. For clinical follow-up tests, measuring the fat assimilation such as steatocrit and breath tests are more suited.
Buscar no Google
Temas:
ECOS
/
Aspectos_gerais
Bases de dados:
MEDLINE
Assunto principal:
Testes de Função Pancreática
/
Insuficiência Pancreática Exócrina
/
Fibrose Cística
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
Idioma:
En
Revista:
Eur J Pediatr
Ano de publicação:
2000
Tipo de documento:
Article
País de afiliação:
Bélgica