Purification and viral inactivation of hemoglobin from human placenta blood.
Artif Cells Blood Substit Immobil Biotechnol
; 37(2): 57-60, 2009.
Article
em En
| MEDLINE
| ID: mdl-19229697
ABSTRACT
A new procedure was developed to obtain high-quality polymerized human hemoglobin by modifying purified hemoglobin with PLP and polymerized with GDA. Comparing polymerized hemoglobin products obtained from different methods, the product from the new procedure has similar physical, chemical, and biological properties in the molecular distribution, methemoglobin concentration, oxygen carrier capacity, P(50) and spectral analysis. Furthermore, the new procedure of modification after polymerization can save PLP greatly, and significantly reduce the cost. So the procedure of modification after polymerization is a better way in research and production.
Texto completo:
1
Temas:
ECOS
/
Aspectos_gerais
Bases de dados:
MEDLINE
Assunto principal:
Placenta
/
Polímeros
/
Fosfato de Piridoxal
/
Hemoglobinas
/
Metemalbumina
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Artif Cells Blood Substit Immobil Biotechnol
Assunto da revista:
BIOTECNOLOGIA
/
TRANSPLANTE
Ano de publicação:
2009
Tipo de documento:
Article
País de afiliação:
China