Epidemiology and management of chronic hepatitis E infection in solid organ transplantation: a comprehensive literature review.
Rev Med Virol
; 23(5): 295-304, 2013 Sep.
Article
em En
| MEDLINE
| ID: mdl-23813631
ABSTRACT
Hepatitis E virus (HEV) infection has emerged as a global public health issue. Although it often causes an acute and self-limiting infection with low mortality rates in the western world, it bears a high risk of developing chronic hepatitis in immunocompromised patients with substantial mortality rates. Organ transplant recipients who receive immunosuppressive medication to prevent rejection are thought to be the main population at risk for chronic hepatitis E. Therefore, there is an urgent need to properly evaluate the clinical impact of HEV in these patients. This article aims to review the prevalence, infection course, and management of HEV infection after solid organ transplantation by performing a comprehensive literature review. In addition, an in-depth emphasis of this clinical issue and a discussion of future development are also presented.
Texto completo:
1
Temas:
ECOS
/
Gestao
Bases de dados:
MEDLINE
Assunto principal:
Transplante de Órgãos
/
Hospedeiro Imunocomprometido
/
Hepatite E
/
Hepatite Crônica
Tipo de estudo:
Prevalence_studies
/
Qualitative_research
/
Risk_factors_studies
/
Screening_studies
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Revista:
Rev Med Virol
Assunto da revista:
VIROLOGIA
Ano de publicação:
2013
Tipo de documento:
Article
País de afiliação:
Holanda