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Design, economical synthesis and antiplasmodial evaluation of vanillin derived allylated chalcones and their marked synergism with artemisinin against chloroquine resistant strains of Plasmodium falciparum.
Sharma, Nandini; Mohanakrishnan, Dinesh; Sharma, Upendra Kumar; Kumar, Rajesh; Sinha, Arun Kumar; Sahal, Dinkar.
Afiliação
  • Sharma N; Natural Plant Products Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur 176061, HP, India.
  • Mohanakrishnan D; Malaria Research Laboratory, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India.
  • Sharma UK; Natural Plant Products Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur 176061, HP, India.
  • Kumar R; Natural Plant Products Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur 176061, HP, India.
  • Richa; Natural Plant Products Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur 176061, HP, India.
  • Sinha AK; Natural Plant Products Division, CSIR-Institute of Himalayan Bioresource Technology, Palampur 176061, HP, India; Medicinal and Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow 226031, UP, India. Electronic address: aksinha08@rediffmail.com.
  • Sahal D; Malaria Research Laboratory, International Centre for Genetic Engineering and Biotechnology, Aruna Asaf Ali Marg, New Delhi 110067, India. Electronic address: dinkar@icgeb.res.in.
Eur J Med Chem ; 79: 350-68, 2014 May 22.
Article em En | MEDLINE | ID: mdl-24747290
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Texto completo: 1 Temas: ECOS / Aspectos_gerais / Avaliacao_economica Bases de dados: MEDLINE Assunto principal: Plasmodium falciparum / Benzaldeídos / Desenho de Fármacos / Artemisininas / Chalconas / Antimaláricos Tipo de estudo: Health_economic_evaluation / Prognostic_studies Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Índia
Texto completo
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Texto completo: 1 Temas: ECOS / Aspectos_gerais / Avaliacao_economica Bases de dados: MEDLINE Assunto principal: Plasmodium falciparum / Benzaldeídos / Desenho de Fármacos / Artemisininas / Chalconas / Antimaláricos Tipo de estudo: Health_economic_evaluation / Prognostic_studies Limite: Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2014 Tipo de documento: Article País de afiliação: Índia