Population pharmacokinetics of piperacillin in the early phase of septic shock: does standard dosing result in therapeutic plasma concentrations?

Öbrink-Hansen, Kristina; Juul, Rasmus Vestergaard; Storgaard, Merete; Thomsen, Marianne Kragh; Hardlei, Tore Forsingdal; Brock, Birgitte; Kreilgaard, Mads; Gjedsted, Jakob

Öbrink-Hansen, Kristina; Juul, Rasmus Vestergaard; Storgaard, Merete; Thomsen, Marianne Kragh; Hardlei, Tore Forsingdal; Brock, Birgitte; Kreilgaard, Mads; Gjedsted, Jakob.

Afiliação

Öbrink-Hansen K; Department of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark krisoebr@rm.dk.
Juul RV; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Storgaard M; Department of Infectious Diseases, Aarhus University Hospital, Skejby, Denmark.
Thomsen MK; Department of Clinical Microbiology, Aarhus University Hospital, Skejby, Denmark.
Hardlei TF; Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark.
Brock B; Department of Clinical Biochemistry, Aarhus University Hospital, Skejby, Denmark.
Kreilgaard M; Department of Drug Design and Pharmacology, University of Copenhagen, Copenhagen, Denmark.
Gjedsted J; Department of Anesthesia and Intensive Care Medicine, Aarhus University Hospital, Skejby, Denmark.

Antimicrob Agents Chemother ; 59(11): 7018-26, 2015 Nov.

Article em En | MEDLINE | ID: mdl-26349823

Assuntos

Antibacterianos/sangue; Antibacterianos/farmacocinética; Piperacilina/sangue; Piperacilina/farmacocinética; Choque Séptico/sangue; Choque Séptico/tratamento farmacológico; Idoso; Antibacterianos/farmacologia; Antibacterianos/uso terapêutico; Feminino; Humanos; Masculino; Testes de Sensibilidade Microbiana; Pessoa de Meia-Idade; Método de Monte Carlo; Ácido Penicilânico/análogos & derivados; Ácido Penicilânico/sangue; Ácido Penicilânico/farmacocinética; Ácido Penicilânico/farmacologia; Ácido Penicilânico/uso terapêutico; Piperacilina/farmacologia; Piperacilina/uso terapêutico; Estudos Prospectivos; Pseudomonas aeruginosa/efeitos dos fármacos; Tazobactam

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Temas: ECOS / Financiamentos_gastos Bases de dados: MEDLINE Assunto principal: Piperacilina / Choque Séptico / Antibacterianos Tipo de estudo: Health_economic_evaluation / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Antimicrob Agents Chemother Ano de publicação: 2015 Tipo de documento: Article País de afiliação: Dinamarca

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google