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Pathologic assessment of computerized tomography accuracy for the evaluation of the laryngeal cartilaginous framework in laryngopharyngeal carcinomas.
Sulfaro, S; Querin, F; Barzan, L; Lutman, M; Comoretto, R; Volpe, R; Carbone, A.
Afiliação
  • Sulfaro S; Division of Pathology, Centro di Riferimento Oncologico, Aviano, Italy.
Tumori ; 75(2): 156-62, 1989 Apr 30.
Article em En | MEDLINE | ID: mdl-2741223
Sixty-six whole-organ sectioned laryngopharyngectomy specimens removed for cancer during a seven-year period were uniformly examined to determine the accuracy of preoperative high resolution computerized tomography (CT) for detection of cartilaginous involvement. Our results indicate that CT has a high overall specificity (88.2%) but a low sensitivity (47.1%); we observed a high false-negative rate (26.5%) and a fairly low false-positive rate (5.9%). Massive cartilage destruction was easily assessed by CT, whereas both small macroscopic and microscopic neoplastic foci of cartilaginous invasion were missed on CT scans. Moreover, false-positive cases were mainly due to proximity of the tumor to the cartilage. Clinical implications of these results are discussed.
Assuntos
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Temas: ECOS / Aspectos_gerais Bases de dados: MEDLINE Assunto principal: Carcinoma / Neoplasias Hipofaríngeas / Neoplasias Faríngeas / Tomografia Computadorizada por Raios X / Neoplasias Laríngeas / Cartilagens Laríngeas Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Tumori Ano de publicação: 1989 Tipo de documento: Article País de afiliação: Itália
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Temas: ECOS / Aspectos_gerais Bases de dados: MEDLINE Assunto principal: Carcinoma / Neoplasias Hipofaríngeas / Neoplasias Faríngeas / Tomografia Computadorizada por Raios X / Neoplasias Laríngeas / Cartilagens Laríngeas Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Tumori Ano de publicação: 1989 Tipo de documento: Article País de afiliação: Itália