Telomere Length Among Older U.S. Adults: Differences by Race/Ethnicity, Gender, and Age.
J Aging Health
; 29(8): 1350-1366, 2017 12.
Article
em En
| MEDLINE
| ID: mdl-27469599
ABSTRACT
OBJECTIVE:
We examine race/ethnic, gender, and age differences in telomere length (TL) within a diverse, nationally representative sample of older adults.METHOD:
Data come from 5,228 White, Black, and Hispanic respondents aged 54+ in the 2008 Health and Retirement Study. TL was assayed from saliva using quantitative polymerase chain reaction (qPCR) by comparing telomere sequence copy number with a single gene copy number (T/S ratio). Linear regression was used to examine TL by race/ethnicity, gender, and age adjusting for social, economic, and health characteristics.RESULTS:
Women had longer TL than men (p < .05). Blacks ( p < .05) and Hispanics ( p < .10) had longer TL than Whites. Black women and men had the longest TL relative to other groups ( p < .05), while White men had the shortest TL ( p < .05). Black women and Hispanic men showed greater differences in TL with age.DISCUSSION:
Findings indicate social patterns in TL by race/ethnicity, gender, and age among older adults do not reflect differences observed in most population health outcomes.Palavras-chave
Texto completo:
1
Temas:
ECOS
/
Equidade_desigualdade
Bases de dados:
MEDLINE
Assunto principal:
Envelhecimento
/
Telômero
Tipo de estudo:
Qualitative_research
Aspecto:
Determinantes_sociais_saude
/
Equity_inequality
/
Patient_preference
Limite:
Aged
/
Female
/
Humans
/
Male
País/Região como assunto:
America do norte
Idioma:
En
Revista:
J Aging Health
Assunto da revista:
GERIATRIA
Ano de publicação:
2017
Tipo de documento:
Article
País de afiliação:
Estados Unidos