Interpreting population reach of a large, successful physical activity trial delivered through primary care.
BMC Public Health
; 18(1): 170, 2018 01 23.
Article
em En
| MEDLINE
| ID: mdl-29361929
ABSTRACT
BACKGROUND:
Failure to include socio-economically deprived or ethnic minority groups in physical activity (PA) trials may limit representativeness and could lead to implementation of interventions that then increase health inequalities. Randomised intervention trials often have low recruitment rates and rarely assess recruitment bias. A previous trial by the same team using similar methods recruited 30% of the eligible population but was in an affluent setting with few non-white residents and was limited to those over 60 years of age.METHODS:
PACE-UP is a large, effective, population-based walking trial in inactive 45-75 year-olds that recruited through seven London general practices. Anonymised practice demographic data were available for all those invited, enabling investigation of inequalities in trial recruitment. Non-participants were invited to complete a questionnaire.RESULTS:
From 10,927 postal invitations, 1150 (10.5%) completed baseline assessment. Participation rate ratios (95% CI), adjusted for age and gender as appropriate, were lower in men 0.59 (0.52, 0.67) than women, in those under 55 compared with those ≥65, 0.60 (0.51, 0.71), in the most deprived quintile compared with the least deprived 0.52 (0.39, 0.70) and in Asian individuals compared with whites 0.62 (0.50, 0.76). Black individuals were equally likely to participate as white individuals. Participation was also associated with having a co-morbidity or some degree of health limitation. The most common reasons for non-participation were considering themselves as being too active or lack of time.CONCLUSIONS:
Conducting the trial in this diverse setting reduced overall response, with lower response in socio-economically deprived and Asian sub-groups. Trials with greater reach are likely to be more expensive in terms of recruitment and gains in generalizability need to be balanced with greater costs. Differential uptake of successful trial interventions may increase inequalities in PA levels and should be monitored. TRIAL REGISTRATION ISRCTN.com ISRCTN98538934 . Registered 2nd March 2012.Palavras-chave
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Temas:
ECOS
/
Equidade_desigualdade
/
Estado_mercado_regulacao
Bases de dados:
MEDLINE
Assunto principal:
Atenção Primária à Saúde
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Exercício Físico
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Participação da Comunidade
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Promoção da Saúde
Tipo de estudo:
Clinical_trials
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Evaluation_studies
Aspecto:
Determinantes_sociais_saude
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Equity_inequality
/
Patient_preference
Limite:
Aged
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Female
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Humans
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Male
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Middle aged
País/Região como assunto:
Europa
Idioma:
En
Revista:
BMC Public Health
Assunto da revista:
SAUDE PUBLICA
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Reino Unido