Consumer use and response to online third-party raw DNA interpretation services.
Mol Genet Genomic Med
; 6(1): 35-43, 2018 01.
Article
em En
| MEDLINE
| ID: mdl-29471590
ABSTRACT
BACKGROUND:
With the availability of raw DNA generated from direct-to-consumer (DTC) testing companies, there has been a proliferation of third-party online services that are available to interpret the raw data for both genealogy and/or health purposes. This study examines the current landscape and downstream clinical implications of consumer use of third-party services.METHODS:
Study participants were recruited online from social media platforms. A total of 321 survey respondents reported using third-party services for raw DNA interpretation.RESULTS:
Participants were highly motivated to explore raw DNA for ancestral information (67%), individual health implications (62%), or both (40%). Participants primarily used one of seven companies to interpret raw DNA; 73% used more than one. Company choice was driven by the type of results offered (51%), price (45%), and online reviews (31%). Approximately 30% of participants shared results with a medical provider and 21% shared with more than one. Outcomes of sharing ranged from disinterest/discounting of the information to diagnosis of genetic conditions. Participants were highly satisfied with their decision to analyze raw DNA (M = 4.54/5), yet challenges in understanding interpretation results were reported irrespective of satisfaction ratings.CONCLUSION:
Consumers face challenges in understanding the results and may seek out clinical assistance in interpreting their raw DNA results.Palavras-chave
Texto completo:
1
Temas:
ECOS
/
Aspectos_gerais
Bases de dados:
MEDLINE
Assunto principal:
Testes Genéticos
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Triagem e Testes Direto ao Consumidor
Tipo de estudo:
Prognostic_studies
Limite:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
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Middle aged
Idioma:
En
Revista:
Mol Genet Genomic Med
Ano de publicação:
2018
Tipo de documento:
Article
País de afiliação:
Estados Unidos