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Pharmacoeconomic evaluation of glimepiride combined with other drugs in the treatment of diabetes.
Liu, Xiufang; Zeng, Liping; Xu, Wenchao.
Afiliação
  • Liu X; Yidu Central Hospital of Weifang, Qingzhou, China.
  • Zeng L; Yidu Central Hospital of Weifang, Qingzhou, China.
  • Xu W; Yidu Central Hospital of Weifang, Endocrine Department, Qingzhou, China.
Pak J Pharm Sci ; 31(3(Special)): 1103-1107, 2018 May.
Article em En | MEDLINE | ID: mdl-29735458
The goal of diabetic drug treatment is to stabilize the blood sugar for a long time to close to the normal level, to correct the metabolic disorder and eliminate the symptoms. At present, glimepiride has become commonly used drugs for the treatment of diabetes with obesity. Compared with metformin, acarbose and rosiglitazone, glimepiride has different mechanisms of drug action, clinical combination showed synergistic hypoglycemic effect, good clinical curative effect. So, we use three treatments to study as group A (glimepiride and metformin); group B (glimepiride and acarbose); Group C (glimepiride and rosiglitazone). From the analysis of drug economics, glimepiride and metformin scheme is better, has the lowest cost per unit cost effect. From the comparison of scheme is efficient, the best curative effect is rosiglitazone plus glimepiride, effective rate as 96.7%. At the same time, the drug can be rationally used to reduce the occurrence of some drug-induced diseases and adverse drug reactions.
Assuntos
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Temas: ECOS / Aspectos_gerais Bases de dados: MEDLINE Assunto principal: Compostos de Sulfonilureia / Farmacoeconomia / Diabetes Mellitus Tipo 2 Tipo de estudo: Clinical_trials / Health_economic_evaluation Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Pak J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China
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Temas: ECOS / Aspectos_gerais Bases de dados: MEDLINE Assunto principal: Compostos de Sulfonilureia / Farmacoeconomia / Diabetes Mellitus Tipo 2 Tipo de estudo: Clinical_trials / Health_economic_evaluation Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Pak J Pharm Sci Assunto da revista: FARMACIA / FARMACOLOGIA / QUIMICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: China