Antibiotic exposure at the site of infection: principles and assessment of tissue penetration.

Jager, Nynke G L; van Hest, Reinier M; Lipman, Jeffrey; Roberts, Jason A; Cotta, Menino O

Jager, Nynke G L; van Hest, Reinier M; Lipman, Jeffrey; Roberts, Jason A; Cotta, Menino O.

Afiliação

Jager NGL; a University of Queensland Centre for Clinical Research, The University of Queensland , Brisbane , Australia.
van Hest RM; b Department of Hospital Pharmacy - Clinical Pharmacology Unit, Amsterdam UMC , University of Amsterdam , Amsterdam , the Netherlands.
Lipman J; b Department of Hospital Pharmacy - Clinical Pharmacology Unit, Amsterdam UMC , University of Amsterdam , Amsterdam , the Netherlands.
Roberts JA; a University of Queensland Centre for Clinical Research, The University of Queensland , Brisbane , Australia.
Cotta MO; c Departments of Pharmacy and Intensive Care , Royal Brisbane and Women's Hospital , Brisbane , Australia.

Expert Rev Clin Pharmacol ; 12(7): 623-634, 2019 Jul.

Article em En | MEDLINE | ID: mdl-31136211

Assuntos

Antibacterianos/administração & dosagem; Infecções Bacterianas/tratamento farmacológico; Monitoramento de Medicamentos/métodos; Antibacterianos/farmacocinética; Relação Dose-Resposta a Droga; Humanos; Distribuição Tecidual

Palavras-chave

Antibiotics; infection; microdialysis; pharmacokinetic; tissue distribution; tissue penetration

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Texto completo: 1 Temas: ECOS / Aspectos_gerais Bases de dados: MEDLINE Assunto principal: Infecções Bacterianas / Monitoramento de Medicamentos / Antibacterianos Limite: Humans Idioma: En Revista: Expert Rev Clin Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Austrália

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