Assessment of fetal blood volume for computer-assisted management of in utero transfusion.
Fetal Ther
; 3(1-2): 60-6, 1988.
Article
em En
| MEDLINE
| ID: mdl-3257068
ABSTRACT
We performed 41 intravascular ultrasound-guided fetal transfusions in a total of 20 pregnancies with erythroblastosis fetalis or alloimmune thrombocytopenia. On the basis of this experience, we developed a computer-assisted procedure for determining the volume to be transfused, which provides an adequate final concentration. Fetal weight was estimated using ultrasound measurements. Fetoplacental blood volume was estimated from the regression line fetoplacental volume (ml) = 1.046 + fetal weight (g) X 0.14. The volume to be transfused was calculated using the simple dilution formula Vtransfused = Vfetoplacental.(Cfinal - Cinitial)/Ctransfused where C is the hematocrit or platelet count. The entire procedure is computerized, simple and rapid, and avoids resorting to repeated intermediate sampling. The dilution formula used appears to be more reliable than a formula taking into account the volume added, even in erythroblastosis fetalis where relatively large volumes are injected. This suggests rapid plasma loss during the procedure.
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Temas:
ECOS
/
Aspectos_gerais
Bases de dados:
MEDLINE
Assunto principal:
Transfusão de Sangue Intrauterina
/
Volume Sanguíneo
/
Simulação por Computador
/
Computação Matemática
/
Análise Numérica Assistida por Computador
/
Sangue Fetal
Limite:
Female
/
Humans
/
Pregnancy
Idioma:
En
Revista:
Fetal Ther
Assunto da revista:
DIAGNOSTICO POR IMAGEM
/
OBSTETRICIA
/
PERINATOLOGIA
Ano de publicação:
1988
Tipo de documento:
Article
País de afiliação:
França