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Considerations for diagnostic COVID-19 tests.
Vandenberg, Olivier; Martiny, Delphine; Rochas, Olivier; van Belkum, Alex; Kozlakidis, Zisis.
Afiliação
  • Vandenberg O; Innovation and Business Development Unit, Laboratoire Hospitalier Universtaire de Bruxelles - Universitair Laboratorium Brussel, Université Libre de Bruxelles, Brussels, Belgium. olivier.vandenberg@lhub-ulb.be.
  • Martiny D; Center for Environmental Health and Occupational Health, School of Public Health, Université Libre de Bruxelles, Brussels, Belgium. olivier.vandenberg@lhub-ulb.be.
  • Rochas O; Division of Infection and Immunity, Faculty of Medical Sciences, University College London, London, UK. olivier.vandenberg@lhub-ulb.be.
  • van Belkum A; Department of Microbiology, Laboratoire Hospitalier Universtaire de Bruxelles - Universitair Laboratorium Brussel, Université Libre de Bruxelles, Brussels, Belgium.
  • Kozlakidis Z; Strategic Intelligence, Corporate Business Development, bioMérieux, Chemin de L'Orme, France.
Nat Rev Microbiol ; 19(3): 171-183, 2021 03.
Article em En | MEDLINE | ID: mdl-33057203
ABSTRACT
During the early phase of the coronavirus disease 2019 (COVID-19) pandemic, design, development, validation, verification and implementation of diagnostic tests were actively addressed by a large number of diagnostic test manufacturers. Hundreds of molecular tests and immunoassays were rapidly developed, albeit many still await clinical validation and formal approval. In this Review, we summarize the crucial role of diagnostic tests during the first global wave of COVID-19. We explore the technical and implementation problems encountered during this early phase in the pandemic, and try to define future directions for the progressive and better use of (syndromic) diagnostics during a possible resurgence of COVID-19 in future global waves or regional outbreaks. Continuous global improvement in diagnostic test preparedness is essential for more rapid detection of patients, possibly at the point of care, and for optimized prevention and treatment, in both industrialized countries and low-resource settings.
Assuntos

Texto completo: 1 Temas: ECOS / Aspectos_gerais Bases de dados: MEDLINE Assunto principal: Teste para COVID-19 / SARS-CoV-2 Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Nat Rev Microbiol Assunto da revista: MICROBIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Bélgica

Texto completo: 1 Temas: ECOS / Aspectos_gerais Bases de dados: MEDLINE Assunto principal: Teste para COVID-19 / SARS-CoV-2 Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Nat Rev Microbiol Assunto da revista: MICROBIOLOGIA Ano de publicação: 2021 Tipo de documento: Article País de afiliação: Bélgica