Cord blood beyond transplantation: can we use the experience to advance all cell therapies?
Br J Haematol
; 194(1): 14-27, 2021 07.
Article
em En
| MEDLINE
| ID: mdl-33529385
ABSTRACT
Unrelated cord blood (CB) units, already manufactured, fully tested and stored, are high-quality products for haematopoietic stem cell transplantation and cell therapies, as well as an optimal starting material for cell expansion, cell engineering or cell re-programming technologies. CB banks have been pioneers in the development and implementation of Current Good Manufacturing Practices for cell-therapy products. Sharing their technological and regulatory experience will help advance all cell therapies, CB-derived or not, particularly as they transition from autologous, individually manufactured products to stored, 'off-the shelf' treatments. Such strategies will allow broader patient access and wide product utilisation.
Palavras-chave
Texto completo:
1
Temas:
ECOS
/
Aspectos_gerais
Bases de dados:
MEDLINE
Assunto principal:
Bancos de Sangue
/
Sangue Fetal
/
Terapia Baseada em Transplante de Células e Tecidos
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
País/Região como assunto:
America do norte
/
Europa
Idioma:
En
Revista:
Br J Haematol
Ano de publicação:
2021
Tipo de documento:
Article
País de afiliação:
Estados Unidos