Chronic Nonbacterial Osteomyelitis: Insights into Pathogenesis, Assessment, and Treatment.
Rheum Dis Clin North Am
; 47(4): 691-705, 2021 11.
Article
em En
| MEDLINE
| ID: mdl-34635299
ABSTRACT
Chronic nonbacterial osteomyelitis, or its most severe form, chronic recurrent multifocal osteomyelitis, is an autoinflammatory bone disease that causes skeletal inflammation characterized by bone pain and swelling that primarily affects children. It is a diagnosis of exclusion and its clinical presentation may mimic underlying infectious processes and malignancy. Clinical suspicion for this diagnosis and timely referral to pediatric rheumatology is crucial to achieve earlier diagnosis, appropriate treatment, and improved quality of life of affected patients and families. This article focuses on recent insights into the pathogenesis of chronic nonbacterial osteomyelitis and outlines recent advances and ongoing research.
Palavras-chave
Texto completo:
1
Temas:
ECOS
/
Aspectos_gerais
Bases de dados:
MEDLINE
Assunto principal:
Osteomielite
/
Qualidade de Vida
Tipo de estudo:
Diagnostic_studies
/
Etiology_studies
Aspecto:
Patient_preference
Limite:
Child
/
Humans
Idioma:
En
Revista:
Rheum Dis Clin North Am
Assunto da revista:
REUMATOLOGIA
Ano de publicação:
2021
Tipo de documento:
Article