Assessment of the nlmixr R package for population pharmacokinetic modeling: A metformin case study.

Mak, Wen Yao; Ooi, Qing Xi; Cruz, Cintia Valeria; Looi, Irene; Yuen, Kah Hay; Standing, Joseph F

Mak, Wen Yao; Ooi, Qing Xi; Cruz, Cintia Valeria; Looi, Irene; Yuen, Kah Hay; Standing, Joseph F.

Afiliação

Mak WY; Clinical Research Centre, Penang General Hospital, Penang, Malaysia.
Ooi QX; Institute for Clinical Research, National Institute of Health, Selangor, Malaysia.
Cruz CV; Pharmetheus AB, Uppsala, Sweden.
Looi I; Mahidol Oxford Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.
Yuen KH; Clinical Research Centre, Seberang Jaya Hospital, Penang, Malaysia.
Standing JF; School of Pharmaceutical Sciences, Universiti Sains Malaysia, Penang, Malaysia.

Br J Clin Pharmacol ; 89(1): 330-339, 2023 01.

Article em En | MEDLINE | ID: mdl-35976674

Assuntos

Algoritmos; Modelos Biológicos; Humanos; Simulação por Computador; Farmacocinética

Palavras-chave

modelling and simulation; pharmacokinetics; pharmacometrics

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Texto completo: 1 Temas: ECOS / Aspectos_gerais Bases de dados: MEDLINE Assunto principal: Algoritmos / Modelos Biológicos Limite: Humans Idioma: En Revista: Br J Clin Pharmacol Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Malásia

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