A novel integrated biomarker index for the assessment of hematological responses in MPNs during treatment with hydroxyurea and interferon-alpha2.

Dam, Marc J B; Pedersen, Rasmus K; Knudsen, Trine A; Andersen, Morten; Ellervik, Christina; Larsen, Morten Kranker; Kjaer, Lasse; Skov, Vibe; Hasselbalch, Hans C; Ottesen, Johnny T

Dam, Marc J B; Pedersen, Rasmus K; Knudsen, Trine A; Andersen, Morten; Ellervik, Christina; Larsen, Morten Kranker; Kjaer, Lasse; Skov, Vibe; Hasselbalch, Hans C; Ottesen, Johnny T.

Afiliação

Dam MJB; Centre for Mathematical Modeling - Human Health and Disease (COMMAND), IMFUFA, Department of Science and Environment, Roskilde University, Roskilde, Denmark.
Pedersen RK; Centre for Mathematical Modeling - Human Health and Disease (COMMAND), IMFUFA, Department of Science and Environment, Roskilde University, Roskilde, Denmark.
Knudsen TA; Department of Haematology, Zealand University Hospital, Roskilde, Denmark.
Andersen M; Centre for Mathematical Modeling - Human Health and Disease (COMMAND), IMFUFA, Department of Science and Environment, Roskilde University, Roskilde, Denmark.
Ellervik C; Department of Research, Production, Innovation, Region Zealand, Sorø, Denmark.
Larsen MK; Department of Pathology, Harvard Medical School, Boston, Massachusetts, USA.
Kjaer L; Department of Haematology, Zealand University Hospital, Roskilde, Denmark.
Skov V; Department of Haematology, Zealand University Hospital, Roskilde, Denmark.
Hasselbalch HC; Department of Haematology, Zealand University Hospital, Roskilde, Denmark.
Ottesen JT; Department of Haematology, Zealand University Hospital, Roskilde, Denmark.

Cancer Med ; 12(4): 4218-4226, 2023 02.

Article em En | MEDLINE | ID: mdl-36254099

Assuntos

Transtornos Mieloproliferativos; Policitemia Vera; Humanos; Hidroxiureia/efeitos adversos; Policitemia Vera/tratamento farmacológico; Interferon-alfa/efeitos adversos; Transtornos Mieloproliferativos/diagnóstico; Transtornos Mieloproliferativos/tratamento farmacológico; Biomarcadores

Palavras-chave

MPN; combination therapy; essential thrombocythemia; hydroxyurea; interferon-alpha2; myelofibrosis; novel integrated biomarker index; polycythemia vera; treatment responses

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Texto completo: 1 Temas: ECOS / Aspectos_gerais Bases de dados: MEDLINE Assunto principal: Policitemia Vera / Transtornos Mieloproliferativos Limite: Humans Idioma: En Revista: Cancer Med Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Dinamarca

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