<i>In vitro</i> genotoxicity assessment and 28-day repeated dose oral toxicity study of steady-calcium formula in rats.

Chang, Ting-Yu; Lan, Kuo-Cheng; Hua, Kuo-Tai; Liu, Shing-Hwa

In vitro genotoxicity assessment and 28-day repeated dose oral toxicity study of steady-calcium formula in rats.

Chang, Ting-Yu; Lan, Kuo-Cheng; Hua, Kuo-Tai; Liu, Shing-Hwa.

Afiliação

Chang TY; Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Lan KC; Department of Emergency Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
Hua KT; Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Liu SH; Institute of Toxicology, College of Medicine, National Taiwan University, Taipei, Taiwan.

Toxicol Rep ; 9: 834-841, 2022.

Article em En | MEDLINE | ID: mdl-36518413

Palavras-chave

28-day repeated dose oral toxicity; ALK. Phos., alkaline phosphatase; ALT, alanine aminotransferase; APTT, activated partial thromboplastin time; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CHO, Chinese hamster ovary; CPK, creatine phosphate kinase; Chromosomal aberrations; Clastogenicity; Functional food mixture; Genotoxicity; LDH, lactate dehydrogenase; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; MOS, margin of safety; MPV, mean platelet volume; NOAEL, no observed adverse effect level; OECD, organization for economic cooperation and development; PT, prothrombin time; RBC, red blood cell; RDW, red blood cell volume distribution width; SCF, steady-calcium formula; TFDA, Taiwan food and drug administration; WBC, white blood cell; Î³-GT, gamma glutamyl transpeptidase

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Texto completo: 1 Temas: ECOS / Aspectos_gerais Bases de dados: MEDLINE Idioma: En Revista: Toxicol Rep Ano de publicação: 2022 Tipo de documento: Article País de afiliação: Taiwan

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