Sarcopenia and Frailty in Cirrhosis: Assessment and Management.
Med Clin North Am
; 107(3): 589-604, 2023 May.
Article
em En
| MEDLINE
| ID: mdl-37001955
ABSTRACT
Sarcopenia and frailty are frequent in cirrhosis, and both contribute to increased morbidity and mortality. The complex pathogenesis of sarcopenia in cirrhosis is mainly determined by hyperammonemia and malnutrition. Sarcopenia/frailty screening and reevaluation should be undertaken in all cirrhotic patients. Frailty tests are useful in the ambulatory setting, whereas the computed tomography scan is the diagnostic gold standard for sarcopenia. To manage sarcopenia/frailty, a multidisciplinary team should develop a personalized comprehensive care plan that includes patient education, protein/calorie intake goals, late evening meals, exercise programs, and micronutrient replenishment. In selected patients, branched-chain amino acid and testosterone supplements may also be beneficial.
Palavras-chave
Texto completo:
1
Temas:
ECOS
/
Aspectos_gerais
Bases de dados:
MEDLINE
Assunto principal:
Desnutrição
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Sarcopenia
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Fragilidade
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
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Guideline
Aspecto:
Determinantes_sociais_saude
Limite:
Humans
Idioma:
En
Revista:
Med Clin North Am
Ano de publicação:
2023
Tipo de documento:
Article