Comparative toxicity of conventional versus compostable plastic consumer products: An in-vitro assessment.
J Hazard Mater
; 459: 132123, 2023 10 05.
Article
em En
| MEDLINE
| ID: mdl-37499498
ABSTRACT
This study investigates the toxicity of methanolic extracts obtained from compostable plastics (BPs) and conventional plastics (both virgin and recycled). Additionally, it explores the potential influence of plastic photodegradation and composting on toxic responses using a battery of in vitro assays conducted in PLHC-1 cells. The extracts of BPs, but not those of conventional plastics, induced a significant decrease in cell viability (<70%) in PLHC-1 cells after 24 h of exposure. Toxicity was enhanced by either photodegradation or composting of BPs. Extracts of conventional plastics, and particularly those of recycled plastics, induced 7-ethoxyresorufin-O-deethylase (EROD) activity and micronucleus formation in exposed cells, indicating the presence of significant amounts of CYP1A inducers and genotoxic compounds in the extracts, which was enhanced by photodegradation. These findings highlight the importance of investigating the effects of degradation mechanisms such as sunlight and composting on the toxicity of BPs. It is also crucial to investigate the composition of newly developed formulations for BPs, as they may be more harmful than conventional ones.
Palavras-chave
Texto completo:
1
Temas:
ECOS
/
Aspectos_gerais
Bases de dados:
MEDLINE
Assunto principal:
Plásticos Biodegradáveis
Idioma:
En
Revista:
J Hazard Mater
Assunto da revista:
SAUDE AMBIENTAL
Ano de publicação:
2023
Tipo de documento:
Article