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131I dose coefficients for a reference population using age-specific models.
Singh, Pradeep Kumar; Patni, Hemant Kumar; Roy, Rahul; Akar, Deepak Kumar; Sawant, Pramilla D.
Afiliação
  • Singh PK; Internal Dosimetry Section, Radiation Safety Systems Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India.
  • Patni HK; Internal Dosimetry Section, Radiation Safety Systems Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India.
  • Roy R; Internal Dosimetry Section, Radiation Safety Systems Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India.
  • Akar DK; Internal Dosimetry Section, Radiation Safety Systems Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India.
  • Sawant PD; Internal Dosimetry Section, Radiation Safety Systems Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085, India.
J Radiol Prot ; 43(4)2023 11 02.
Article em En | MEDLINE | ID: mdl-37857280
Age-specific dose coefficients are required to assess internal exposure to the general public. This study utilizes reference age-specific biokinetic models of iodine to estimate the total number of nuclear disintegrations ã(rS,τ) occurring in source regions (rS) during the commitment time (τ). Age-specific S values are estimated for 35 target regions due to131I present in 22rSusing data from 10 paediatric reference computational phantoms (representing five ages for both sexes) published recently by the International Commission of Radiation Protection (ICRP). Monte Carlo transport simulations are performed in FLUKA code. The estimated ã(rS,τ) and S values are then used to compute the committed tissue equivalent dose HT(τ) for 27 radiosensitive tissues and dose coefficients e(τ) for all five ages due to inhalation and ingestion of131I. The derived ã(rS,τ) values in the thyroid source are observed to increase with age due to the increased retention of iodine in the thyroid. S values are found to decrease with age, mainly due to an increase in target masses. Generally, HT(τ) values are observed to decrease with age, indicating the predominant behaviour of S values over ã(rS,τ). On average, ingestion dose coefficients are 63% higher than for inhalation in all ages. The maximum contribution to dose coefficients is from the thyroid, accounting for 96% in the case of newborns and 98%-99% for all other ages. Furthermore, the estimated e(τ) values for the reference population are observed to be lower than previously published reference values from the ICRP. The estimated S, HT(τ) and e(τ) values can be used to improve estimations of internal doses to organs/whole body for members of the public in cases of131I exposure. The estimated dose coefficients can also be interpolated for other ages to accurately evaluate the doses received by the general public during131I therapy or during a radiological emergency.
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Texto completo: 1 Temas: ECOS / Financiamentos_gastos Bases de dados: MEDLINE Assunto principal: Iodo / Radioisótopos do Iodo Limite: Child / Female / Humans / Male / Newborn Idioma: En Revista: J Radiol Prot Assunto da revista: RADIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia

Texto completo: 1 Temas: ECOS / Financiamentos_gastos Bases de dados: MEDLINE Assunto principal: Iodo / Radioisótopos do Iodo Limite: Child / Female / Humans / Male / Newborn Idioma: En Revista: J Radiol Prot Assunto da revista: RADIOLOGIA Ano de publicação: 2023 Tipo de documento: Article País de afiliação: Índia