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Anti-rubella seroprevalence assessment in an adult sample population in Italy.
Bechini, Angela; Zanella, Beatrice; Bonito, Benedetta; Betti, Marta; Stancanelli, Enrica; Del Riccio, Marco; Salvati, Cristina; Bonanni, Paolo; Bianchi, Jacopo; Biondi, Ilaria; Chellini, Martina; Innocenti, Maddalena; Manzi, Federico; Paolini, Diana; Sartor, Gino; Baggiani, Lorenzo; Baretti, Simonetta; Della Fonte, Monica; Garofalo, Giorgio; Mereu, Giovanna; Santini, Maria Grazia; Boccalini, Sara.
Afiliação
  • Bechini A; Department of Health Sciences, University of Florence, Florence, Italy.
  • Zanella B; Department of Health Sciences, University of Florence, Florence, Italy.
  • Bonito B; Department of Health Sciences, University of Florence, Florence, Italy.
  • Betti M; Medical School of Specialization in Hygiene and Preventive Medicine, University of Florence, Florence, Italy.
  • Stancanelli E; Medical School of Specialization in Hygiene and Preventive Medicine, University of Florence, Florence, Italy.
  • Del Riccio M; Department of Health Sciences, University of Florence, Florence, Italy.
  • Salvati C; Department of Health Sciences, University of Florence, Florence, Italy.
  • Bonanni P; Department of Health Sciences, University of Florence, Florence, Italy.
  • Bianchi J; Medical School of Specialization in Hygiene and Preventive Medicine, University of Florence, Florence, Italy.
  • Biondi I; Medical School of Specialization in Hygiene and Preventive Medicine, University of Florence, Florence, Italy.
  • Chellini M; Medical School of Specialization in Hygiene and Preventive Medicine, University of Florence, Florence, Italy.
  • Innocenti M; Medical School of Specialization in Hygiene and Preventive Medicine, University of Florence, Florence, Italy.
  • Manzi F; Medical School of Specialization in Hygiene and Preventive Medicine, University of Florence, Florence, Italy.
  • Paolini D; Medical School of Specialization in Hygiene and Preventive Medicine, University of Florence, Florence, Italy.
  • Sartor G; Medical School of Specialization in Hygiene and Preventive Medicine, University of Florence, Florence, Italy.
  • Baggiani L; Azienda USL Toscana Centro, Florence, Italy.
  • Baretti S; Azienda USL Toscana Centro, Florence, Italy.
  • Della Fonte M; Azienda USL Toscana Centro, Florence, Italy.
  • Garofalo G; Azienda USL Toscana Centro, Florence, Italy.
  • Mereu G; Azienda USL Toscana Centro, Florence, Italy.
  • Santini MG; Azienda USL Toscana Centro, Florence, Italy.
  • Boccalini S; Department of Health Sciences, University of Florence, Florence, Italy.
Ann Ig ; 2024 May 02.
Article em En | MEDLINE | ID: mdl-38717344
ABSTRACT

Introduction:

Despite global immunization efforts, rubella remains a public health concern, particularly in high- and middle-income countries. This study focused on rubella seroprevalence in the province of Florence, Italy, aiming to identify susceptibility clusters, especially among women in their childbearing age.

Methods:

A cross-sectional study was conducted between April 2018 and December 2019, enrolling 430 adult subjects (age over 18 years). Serum samples were collected, and anti-rubella antibodies were quantified using the ELISA test. Data were analyzed descriptively and compared by sex, nationality, and age groups using statistical tests.

Results:

The overall rubella seroprevalence was high (92.3%), with no significant differences between genders or nationalities. Among childbearing-age females (18-49 years), the highest seroprevalence was observed in the 30-39 age group (94.1%). However, susceptibility clusters exceeding the 5% threshold set by WHO were identified, especially in females aged 40-49 years (7.0%).

Conclusions:

Despite high overall seroprevalence, the study identified pockets of susceptibility, even in childbearing age women. Continuous monitoring, targeted immunization strategies, and public health interventions are recommended to maintain rubella elimination, emphasizing the importance of sustained vaccination efforts to protect vulnerable populations.
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Texto completo: 1 Temas: ECOS / Aspectos_gerais Bases de dados: MEDLINE Idioma: En Revista: Ann Ig Assunto da revista: MICROBIOLOGIA / SAUDE PUBLICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Itália

Texto completo: 1 Temas: ECOS / Aspectos_gerais Bases de dados: MEDLINE Idioma: En Revista: Ann Ig Assunto da revista: MICROBIOLOGIA / SAUDE PUBLICA Ano de publicação: 2024 Tipo de documento: Article País de afiliação: Itália