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1.
From structure to clinic: Design of a muscarinic M1 receptor agonist with potential to treatment of Alzheimer's disease.
Cell
; 184(24): 5886-5901.e22, 2021 11 24.
Artículo
en Inglés
| MEDLINE | ID: mdl-34822784
2.
When a test is more than just a test: Findings from patient interviews and survey in the trial of a technology to measure antidepressant medication response (the PReDicT Trial).
Compr Psychiatry
; 132: 152467, 2024 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-38608615
3.
Evidence That Sedative Effects of Benzodiazepines Involve Unexpected GABAA Receptor Subtypes: Quantitative Observation Studies in Rhesus Monkeys.
J Pharmacol Exp Ther
; 366(1): 145-157, 2018 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-29720564
4.
Exploring the incidence of inadequate response to antidepressants in the primary care of depression.
Eur Neuropsychopharmacol
; 83: 61-70, 2024 Apr 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-38678794
5.
Digital behavioural signatures reveal trans-diagnostic clusters of Schizophrenia and Alzheimer's disease patients.
Eur Neuropsychopharmacol
; 78: 3-12, 2024 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-37864982
6.
Use of experimental medicine approaches for the development of novel psychiatric treatments based on orexin receptor modulation.
Neurosci Biobehav Rev
; 147: 105107, 2023 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-36828161
7.
Effects of ulotaront on brain circuits of reward, working memory, and emotion processing in healthy volunteers with high or low schizotypy.
Schizophrenia (Heidelb)
; 9(1): 49, 2023 Aug 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-37550314
8.
Predictive validity in drug discovery: what it is, why it matters and how to improve it.
Nat Rev Drug Discov
; 21(12): 915-931, 2022 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-36195754
9.
Validation of the P1vital® Faces Set for Use as Stimuli in Tests of Facial Emotion Recognition.
Front Psychiatry
; 13: 663763, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35222109
10.
Feasibility, acceptability and costs of nurse-led Alpha-Stim cranial electrostimulation to treat anxiety and depression in university students.
BMC Prim Care
; 23(1): 97, 2022 04 29.
Artículo
en Inglés
| MEDLINE | ID: mdl-35488189
11.
Relationships between social withdrawal and facial emotion recognition in neuropsychiatric disorders.
Prog Neuropsychopharmacol Biol Psychiatry
; 113: 110463, 2022 03 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-34718073
12.
Social dysfunction is transdiagnostically associated with default mode network dysconnectivity in schizophrenia and Alzheimer's disease.
World J Biol Psychiatry
; 23(4): 264-277, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-34378488
13.
Effect of disease related biases on the subjective assessment of social functioning in Alzheimer's disease and schizophrenia patients.
J Psychiatr Res
; 145: 302-308, 2022 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33221026
14.
Cross-disorder and disorder-specific deficits in social functioning among schizophrenia and alzheimer's disease patients.
PLoS One
; 17(4): e0263769, 2022.
Artículo
en Inglés
| MEDLINE | ID: mdl-35421108
15.
Accuracy in recognising happy facial expressions is associated with antidepressant response to a NOP receptor antagonist but not placebo treatment.
J Psychopharmacol
; 35(12): 1473-1478, 2021 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-34608842
16.
The clinical effectiveness of using a predictive algorithm to guide antidepressant treatment in primary care (PReDicT): an open-label, randomised controlled trial.
Neuropsychopharmacology
; 46(7): 1307-1314, 2021 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-33637837
17.
Reducing abuse liability of GABAA/benzodiazepine ligands via selective partial agonist efficacy at alpha1 and alpha2/3 subtypes.
J Pharmacol Exp Ther
; 332(1): 4-16, 2010 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-19789360
18.
Optimizing Behavioral Paradigms to Facilitate Development of New Treatments for Anhedonia and Reward Processing Deficits in Schizophrenia and Major Depressive Disorder: Study Protocol.
Front Psychiatry
; 11: 536112, 2020.
Artículo
en Inglés
| MEDLINE | ID: mdl-33250788
19.
In vitro and in vivo properties of 3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)-pyrazolo[1,5-d]-[1,2,4]triazine (MRK-016), a GABAA receptor alpha5 subtype-selective inverse agonist.
J Pharmacol Exp Ther
; 331(2): 470-84, 2009 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-19704033
20.
Value of monitoring negative emotional bias in primary care in England for personalised antidepressant treatment: a modelling study.
Evid Based Ment Health
; 22(4): 145-152, 2019 Nov.
Artículo
en Inglés
| MEDLINE | ID: mdl-31562131