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1.

Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy.

Koller, Emily J; Gonzalez De La Cruz, Elsa; Machula, Timothy; Ibanez, Kristen R; Lin, Wen-Lang; Williams, Tosha; Riffe, Cara J; Ryu, Daniel; Strang, Kevin H; Liu, Xuefei; Janus, Christopher; Golde, Todd E; Dickson, Dennis; Giasson, Benoit I; Chakrabarty, Paramita.

Hum Mol Genet ; 28(19): 3255-3269, 2019 10 01.

Artículo en Inglés | MEDLINE | ID: mdl-31261380

2.

SLC39A14 deficiency alters manganese homeostasis and excretion resulting in brain manganese accumulation and motor deficits in mice.

Jenkitkasemwong, Supak; Akinyode, Adenike; Paulus, Elizabeth; Weiskirchen, Ralf; Hojyo, Shintaro; Fukada, Toshiyuki; Giraldo, Genesys; Schrier, Jessica; Garcia, Armin; Janus, Christopher; Giasson, Benoit; Knutson, Mitchell D.

Proc Natl Acad Sci U S A ; 115(8): E1769-E1778, 2018 02 20.

Artículo en Inglés | MEDLINE | ID: mdl-29437953

3.

Widespread and efficient transduction of spinal cord and brain following neonatal AAV injection and potential disease modifying effect in ALS mice.

Ayers, Jacob I; Fromholt, Susan; Sinyavskaya, Olga; Siemienski, Zoe; Rosario, Awilda M; Li, Andrew; Crosby, Keith W; Cruz, Pedro E; DiNunno, Nadia M; Janus, Christopher; Ceballos-Diaz, Carolina; Borchelt, David R; Golde, Todd E; Chakrabarty, Paramita; Levites, Yona.

Mol Ther ; 23(1): 53-62, 2015 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-25228069

4.

Substantially elevating the levels of αB-crystallin in spinal motor neurons of mutant SOD1 mice does not significantly delay paralysis or attenuate mutant protein aggregation.

Xu, Guilian; Fromholt, Susan; Ayers, Jacob I; Brown, Hilda; Siemienski, Zoe; Crosby, Keith W; Mayer, Christopher A; Janus, Christopher; Borchelt, David R.

J Neurochem ; 133(3): 452-64, 2015 May.

Artículo en Inglés | MEDLINE | ID: mdl-25557022

5.

Lifelong Chronic Sleep Disruption in a Mouse Model of Traumatic Brain Injury.

Morris, Andrew R; Gudenschwager Basso, Erwin K; Gutierrez-Monreal, Miguel A; Arja, Rawad Daniel; Kobeissy, Firas H; Janus, Christopher G; Wang, Kevin K W; Zhu, Jiepei; Liu, Andrew C.

Neurotrauma Rep ; 5(1): 61-73, 2024.

Artículo en Inglés | MEDLINE | ID: mdl-38288298

6.

Hyperdynamic microtubules, cognitive deficits, and pathology are improved in tau transgenic mice with low doses of the microtubule-stabilizing agent BMS-241027.

Barten, Donna M; Fanara, Patrizia; Andorfer, Cathy; Hoque, Nina; Wong, P Y Anne; Husted, Kristofor H; Cadelina, Gregory W; Decarr, Lynn B; Yang, Ling; Liu, Victoria; Fessler, Chancy; Protassio, Joan; Riff, Timothy; Turner, Holly; Janus, Christopher G; Sankaranarayanan, Sethu; Polson, Craig; Meredith, Jere E; Gray, Gemma; Hanna, Amanda; Olson, Richard E; Kim, Soong-Hoon; Vite, Gregory D; Lee, Francis Y; Albright, Charles F.

J Neurosci ; 32(21): 7137-45, 2012 May 23.

Artículo en Inglés | MEDLINE | ID: mdl-22623658

7.

Sleep Disruption in a Mouse Model of Chronic Traumatic Brain Injury.

Morris, Andrew R; Gudenschwager Basso, Erwin K; Gutierrez-Monreal, Miguel A; Arja, Rawad Daniel; Kobeissy, Firas H; Janus, Christopher G; Wang, Kevin K W; Zhu, Jiepei; Liu, Andrew C.

bioRxiv ; 2023 Nov 14.

Artículo en Inglés | MEDLINE | ID: mdl-38014315

8.

IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice.

Chakrabarty, Paramita; Ceballos-Diaz, Carolina; Beccard, Amanda; Janus, Christopher; Dickson, Dennis; Golde, Todd E; Das, Pritam.

J Immunol ; 184(9): 5333-43, 2010 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-20368278

9.

Soluble brain homogenates from diverse human and mouse sources preferentially seed diffuse Aß plaque pathology when injected into newborn mouse hosts.

Moore, Brenda D; Levites, Yona; Xu, Guilian; Hampton, Hailey; Adamo, Munir F; Croft, Cara L; Futch, Hunter S; Moran, Corey; Fromholt, Susan; Janus, Christopher; Prokop, Stefan; Dickson, Dennis; Lewis, Jada; Giasson, Benoit I; Golde, Todd E; Borchelt, David R.

Free Neuropathol ; 3(9)2022 Jan 11.

Artículo en Inglés | MEDLINE | ID: mdl-35494163

10.

Phenotypic evaluation of a childhood-onset parkinsonism-dystonia mouse model with inherent postural abnormalities.

Giraldo, Genesys; Janus, Christopher.

Brain Res Bull ; 166: 54-63, 2021 01.

Artículo en Inglés | MEDLINE | ID: mdl-33147520

11.

Homing in on intracellular Abeta?

Golde, Todd E; Janus, Christopher.

Neuron ; 45(5): 639-42, 2005 Mar 03.

Artículo en Inglés | MEDLINE | ID: mdl-15748837

12.

An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes.

Futch, Hunter S; McFarland, Karen N; Moore, Brenda D; Kuhn, M Zino; Giasson, Benoit I; Ladd, Thomas B; Scott, Karen A; Shapiro, Melanie R; Nosacka, Rachel L; Goodwin, Marshall S; Ran, Yong; Cruz, Pedro E; Ryu, Daniel H; Croft, Cara L; Levites, Yona; Janus, Christopher; Chakrabarty, Paramita; Judge, Andrew R; Brusko, Todd M; de Kloet, Annette D; Krause, Eric G; Golde, Todd E.

J Exp Med ; 216(11): 2479-2491, 2019 11 04.

Artículo en Inglés | MEDLINE | ID: mdl-31467037

13.

Abnormal spine morphology and enhanced LTP in LIMK-1 knockout mice.

Meng, Yanghong; Zhang, Yu; Tregoubov, Vitali; Janus, Christopher; Cruz, Luis; Jackson, Mike; Lu, Wei Yang; MacDonald, John F; Wang, Jay Y; Falls, Douglas L; Jia, Zhengping.

Neuron ; 35(1): 121-33, 2002 Jul 03.

Artículo en Inglés | MEDLINE | ID: mdl-12123613

14.

Accumulation of pathological tau species and memory loss in a conditional model of tauopathy.

Berger, Zdenek; Roder, Hanno; Hanna, Amanda; Carlson, Aaron; Rangachari, Vijayaraghavan; Yue, Mei; Wszolek, Zbigniew; Ashe, Karen; Knight, Joshua; Dickson, Dennis; Andorfer, Cathy; Rosenberry, Terrone L; Lewis, Jada; Hutton, Mike; Janus, Christopher.

J Neurosci ; 27(14): 3650-62, 2007 Apr 04.

Artículo en Inglés | MEDLINE | ID: mdl-17409229

15.

Locomotor differences in mice expressing wild-type human α-synuclein.

Giraldo, Genesys; Brooks, Mieu; Giasson, Benoit I; Janus, Christopher.

Neurobiol Aging ; 65: 140-148, 2018 05.

Artículo en Inglés | MEDLINE | ID: mdl-29477894

16.

Short Aß peptides attenuate Aß42 toxicity in vivo.

Moore, Brenda D; Martin, Jason; de Mena, Lorena; Sanchez, Jonatan; Cruz, Pedro E; Ceballos-Diaz, Carolina; Ladd, Thomas B; Ran, Yong; Levites, Yona; Kukar, Thomas L; Kurian, Justin J; McKenna, Robert; Koo, Edward H; Borchelt, David R; Janus, Christopher; Rincon-Limas, Diego; Fernandez-Funez, Pedro; Golde, Todd E.

J Exp Med ; 215(1): 283-301, 2018 01 02.

Artículo en Inglés | MEDLINE | ID: mdl-29208777

17.

TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease.

Chakrabarty, Paramita; Li, Andrew; Ladd, Thomas B; Strickland, Michael R; Koller, Emily J; Burgess, Jeremy D; Funk, Cory C; Cruz, Pedro E; Allen, Mariet; Yaroshenko, Mariya; Wang, Xue; Younkin, Curtis; Reddy, Joseph; Lohrer, Benjamin; Mehrke, Leonie; Moore, Brenda D; Liu, Xuefei; Ceballos-Diaz, Carolina; Rosario, Awilda M; Medway, Christopher; Janus, Christopher; Li, Hong-Dong; Dickson, Dennis W; Giasson, Benoit I; Price, Nathan D; Younkin, Steven G; Ertekin-Taner, Nilüfer; Golde, Todd E.

J Exp Med ; 215(9): 2247-2264, 2018 09 03.

Artículo en Inglés | MEDLINE | ID: mdl-30158114

18.

Short amyloid-beta (Abeta) immunogens reduce cerebral Abeta load and learning deficits in an Alzheimer's disease mouse model in the absence of an Abeta-specific cellular immune response.

Maier, Marcel; Seabrook, Timothy J; Lazo, Noel D; Jiang, Liying; Das, Pritam; Janus, Christopher; Lemere, Cynthia A.

J Neurosci ; 26(18): 4717-28, 2006 May 03.

Artículo en Inglés | MEDLINE | ID: mdl-16672644

19.

The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition.

Eskandari-Sedighi, Ghazaleh; Daude, Nathalie; Gapeshina, Hristina; Sanders, David W; Kamali-Jamil, Razieh; Yang, Jing; Shi, Beipei; Wille, Holger; Ghetti, Bernardino; Diamond, Marc I; Janus, Christopher; Westaway, David.

Mol Neurodegener ; 12(1): 72, 2017 10 04.

Artículo en Inglés | MEDLINE | ID: mdl-28978354

20.

Abnormal long-lasting synaptic plasticity and cognition in mice lacking the mental retardation gene Pak3.

Meng, Jinsong; Meng, Yanghong; Hanna, Amanda; Janus, Christopher; Jia, Zhengping.

J Neurosci ; 25(28): 6641-50, 2005 Jul 13.

Artículo en Inglés | MEDLINE | ID: mdl-16014725

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