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1.

Phosphorylation of RXRα mediates the effect of JNK to suppress hepatic FGF21 expression and promote metabolic syndrome.

Vernia, Santiago; Lee, Alexandra; Kennedy, Norman J; Han, Myoung Sook; Isasa, Marta; Cavanagh-Kyros, Julie; Roy, Armanda; Syed, Aafreen; Chaudhry, Shanzah; Edwards, Yvonne J K; Gygi, Steven P; Gao, Guangping; Davis, Roger J.

Proc Natl Acad Sci U S A ; 119(44): e2210434119, 2022 11.

Artículo en Inglés | MEDLINE | ID: mdl-36282921

2.

Cutting Edge: Early Attrition of Memory T Cells during Inflammation and Costimulation Blockade Is Regulated Concurrently by Proapoptotic Proteins Fas and Bim.

Jangalwe, Sonal; Kapoor, Varun N; Xu, Jia; Girnius, Nomeda; Kennedy, Norman J; Edwards, Yvonne J K; Welsh, Raymond M; Davis, Roger J; Brehm, Michael A.

J Immunol ; 202(3): 647-651, 2019 02 01.

Artículo en Inglés | MEDLINE | ID: mdl-30610162

3.

High-fat diet in a mouse insulin-resistant model induces widespread rewiring of the phosphotyrosine signaling network.

Dittmann, Antje; Kennedy, Norman J; Soltero, Nina L; Morshed, Nader; Mana, Miyeko D; Yilmaz, Ömer H; Davis, Roger J; White, Forest M.

Mol Syst Biol ; 15(8): e8849, 2019 08.

Artículo en Inglés | MEDLINE | ID: mdl-31464373

4.

JIP1-Mediated JNK Activation Negatively Regulates Synaptic Plasticity and Spatial Memory.

Morel, Caroline; Sherrin, Tessi; Kennedy, Norman J; Forest, Kelly H; Avcioglu Barutcu, Seda; Robles, Michael; Carpenter-Hyland, Ezekiel; Alfulaij, Naghum; Standen, Claire L; Nichols, Robert A; Benveniste, Morris; Davis, Roger J; Todorovic, Cedomir.

J Neurosci ; 38(15): 3708-3728, 2018 04 11.

Artículo en Inglés | MEDLINE | ID: mdl-29540552

5.

Regulation of Adipose Tissue Inflammation and Insulin Resistance by MAPK Phosphatase 5.

Zhang, Yongliang; Nguyen, Thang; Tang, Peng; Kennedy, Norman J; Jiao, Huipeng; Zhang, Mingliang; Reynolds, Joseph M; Jaeschke, Anja; Martin-Orozco, Natalia; Chung, Yeonseok; He, Wei-min; Wang, Chen; Jia, Weiping; Ge, Baoxue; Davis, Roger J; Flavell, Richard A; Dong, Chen.

J Biol Chem ; 290(24): 14875-83, 2015 Jun 12.

Artículo en Inglés | MEDLINE | ID: mdl-25922079

6.

A radical role for p38 MAPK in tumor initiation.

Kennedy, Norman J; Cellurale, Cristina; Davis, Roger J.

Cancer Cell ; 11(2): 101-3, 2007 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-17292820

7.

Identification of the JNK signaling pathway as a functional target of the tumor suppressor PTEN.

Vivanco, Igor; Palaskas, Nicolaos; Tran, Chris; Finn, Stephen P; Getz, Gad; Kennedy, Norman J; Jiao, Jing; Rose, Joshua; Xie, Wanling; Loda, Massimo; Golub, Todd; Mellinghoff, Ingo K; Davis, Roger J; Wu, Hong; Sawyers, Charles L.

Cancer Cell ; 11(6): 555-69, 2007 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-17560336

8.

Regulation of innate and adaptive immune responses by MAP kinase phosphatase 5.

Zhang, Yongliang; Blattman, Joseph N; Kennedy, Norman J; Duong, Julie; Nguyen, Thang; Wang, Ying; Davis, Roger J; Greenberg, Philip D; Flavell, Richard A; Dong, Chen.

Nature ; 430(7001): 793-7, 2004 Aug 12.

Artículo en Inglés | MEDLINE | ID: mdl-15306813

9.

Neutrophil infiltration regulates clock-gene expression to organize daily hepatic metabolism.

Crespo, María; Gonzalez-Teran, Barbara; Nikolic, Ivana; Mora, Alfonso; Folgueira, Cintia; Rodríguez, Elena; Leiva-Vega, Luis; Pintor-Chocano, Aránzazu; Fernández-Chacón, Macarena; Ruiz-Garrido, Irene; Cicuéndez, Beatriz; Tomás-Loba, Antonia; A-Gonzalez, Noelia; Caballero-Molano, Ainoa; Beiroa, Daniel; Hernández-Cosido, Lourdes; Torres, Jorge L; Kennedy, Norman J; Davis, Roger J; Benedito, Rui; Marcos, Miguel; Nogueiras, Ruben; Hidalgo, Andrés; Matesanz, Nuria; Leiva, Magdalena; Sabio, Guadalupe.

Elife ; 92020 12 08.

Artículo en Inglés | MEDLINE | ID: mdl-33287957

10.

c-Jun NH(2)-terminal kinase is essential for the regulation of AP-1 by tumor necrosis factor.

Ventura, Juan-Jose; Kennedy, Norman J; Lamb, Jennifer A; Flavell, Richard A; Davis, Roger J.

Mol Cell Biol ; 23(8): 2871-82, 2003 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-12665585

11.

The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase.

Lei, Kui; Nimnual, Anjaruwee; Zong, Wei-Xing; Kennedy, Norman J; Flavell, Richard A; Thompson, Craig B; Bar-Sagi, Dafna; Davis, Roger J.

Mol Cell Biol ; 22(13): 4929-42, 2002 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-12052897

12.

Hyper- and hypo- nutrition studies of the hepatic transcriptome and epigenome suggest that PPARα regulates anaerobic glycolysis.

Soltis, Anthony R; Motola, Shmulik; Vernia, Santiago; Ng, Christopher W; Kennedy, Norman J; Dalin, Simona; Matthews, Bryan J; Davis, Roger J; Fraenkel, Ernest.

Sci Rep ; 7(1): 174, 2017 03 14.

Artículo en Inglés | MEDLINE | ID: mdl-28282965

13.

Hepatic Dysfunction Caused by Consumption of a High-Fat Diet.

Soltis, Anthony R; Kennedy, Norman J; Xin, Xiaofeng; Zhou, Feng; Ficarro, Scott B; Yap, Yoon Sing; Matthews, Bryan J; Lauffenburger, Douglas A; White, Forest M; Marto, Jarrod A; Davis, Roger J; Fraenkel, Ernest.

Cell Rep ; 21(11): 3317-3328, 2017 Dec 12.

Artículo en Inglés | MEDLINE | ID: mdl-29241556

14.

Excitatory transmission onto AgRP neurons is regulated by cJun NH2-terminal kinase 3 in response to metabolic stress.

Vernia, Santiago; Morel, Caroline; Madara, Joseph C; Cavanagh-Kyros, Julie; Barrett, Tamera; Chase, Kathryn; Kennedy, Norman J; Jung, Dae Young; Kim, Jason K; Aronin, Neil; Flavell, Richard A; Lowell, Bradford B; Davis, Roger J.

Elife ; 5: e10031, 2016 Feb 24.

Artículo en Inglés | MEDLINE | ID: mdl-26910012

15.

Role of JNK in tumor development.

Kennedy, Norman J; Davis, Roger J.

Cell Cycle ; 2(3): 199-201, 2003.

Artículo en Inglés | MEDLINE | ID: mdl-12734425

16.

Novel Observations From Next-Generation RNA Sequencing of Highly Purified Human Adult and Fetal Islet Cell Subsets.

Blodgett, David M; Nowosielska, Anetta; Afik, Shaked; Pechhold, Susanne; Cura, Anthony J; Kennedy, Norman J; Kim, Soyoung; Kucukural, Alper; Davis, Roger J; Kent, Sally C; Greiner, Dale L; Garber, Manuel G; Harlan, David M; diIorio, Philip.

Diabetes ; 64(9): 3172-81, 2015 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-25931473

17.

Analysis of in vitro insulin-resistance models and their physiological relevance to in vivo diet-induced adipose insulin resistance.

Lo, Kinyui Alice; Labadorf, Adam; Kennedy, Norman J; Han, Myoung Sook; Yap, Yoon Sing; Matthews, Bryan; Xin, Xiaofeng; Sun, Lei; Davis, Roger J; Lodish, Harvey F; Fraenkel, Ernest.

Cell Rep ; 5(1): 259-70, 2013 Oct 17.

Artículo en Inglés | MEDLINE | ID: mdl-24095730

18.

Requirement of c-Jun NH(2)-terminal kinase for Ras-initiated tumor formation.

Cellurale, Cristina; Sabio, Guadalupe; Kennedy, Norman J; Das, Madhumita; Barlow, Marissa; Sandy, Peter; Jacks, Tyler; Davis, Roger J.

Mol Cell Biol ; 31(7): 1565-76, 2011 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-21282468

19.

Role of muscle c-Jun NH2-terminal kinase 1 in obesity-induced insulin resistance.

Sabio, Guadalupe; Kennedy, Norman J; Cavanagh-Kyros, Julie; Jung, Dae Young; Ko, Hwi Jin; Ong, Helena; Barrett, Tamera; Kim, Jason K; Davis, Roger J.

Mol Cell Biol ; 30(1): 106-15, 2010 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-19841069

20.

Signal transduction cross talk mediated by Jun N-terminal kinase-interacting protein and insulin receptor substrate scaffold protein complexes.

Standen, Claire L; Kennedy, Norman J; Flavell, Richard A; Davis, Roger J.

Mol Cell Biol ; 29(17): 4831-40, 2009 Sep.

Artículo en Inglés | MEDLINE | ID: mdl-19564410

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