Detalles de la búsqueda
1.
Pharmacokinetic evaluation of oxaliplatin combined with S-1 (SOX) chemotherapy in a rat model of colorectal cancer with acute kidney injury: predictive renal biomarkers for dose optimisation.
Xenobiotica
; 53(10-11): 613-620, 2023.
Artículo
en Inglés
| MEDLINE | ID: mdl-37966716
2.
Predictive marker for exposure-driven haematological toxicity of tegafur-uracil and proposed modified-dosage regimen by pharmacometric approach in rats.
Xenobiotica
; 52(7): 697-706, 2022 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-36412205
3.
Comparing the pharmacokinetics and organ/tissue distribution of anti-methicillin-resistant Staphylococcus aureus agents using a rat model of sepsis.
Xenobiotica
; 52(6): 583-590, 2022 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-35815433
4.
Mechanism-based pharmacokinetic-pharmacodynamic (PK-PD) modeling and simulation of oxaliplatin for hematological toxicity in rats.
Xenobiotica
; 50(2): 223-230, 2020 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-30938550
5.
Pharmacokinetics and lung distribution of macrolide antibiotics in sepsis model rats.
Xenobiotica
; 50(5): 552-558, 2020 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-31424300
6.
Association between the pharmacokinetics of capecitabine and the plasma dihydrouracil to uracil ratio in rat: A surrogate biomarker for dihydropyrimidine dehydrogenase activity.
Biopharm Drug Dispos
; 40(1): 44-48, 2019 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-30592773
7.
Susceptibility to serious skin and subcutaneous tissue disorders and skin tissue distribution of sodium-dependent glucose co-transporter type 2 (SGLT2) inhibitors.
Int J Med Sci
; 15(9): 937-943, 2018.
Artículo
en Inglés
| MEDLINE | ID: mdl-30008607
8.
Dissolving Microneedles as Skin Allergy Test Device.
Biol Pharm Bull
; 40(4): 531-534, 2017.
Artículo
en Inglés
| MEDLINE | ID: mdl-28381808
9.
Transport of Azithromycin into Extravascular Space in Rats.
Antimicrob Agents Chemother
; 60(11): 6823-6827, 2016 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27600045
10.
Therapeutic Drug Monitoring of Vancomycin in Dermal Interstitial Fluid Using Dissolving Microneedles.
Int J Med Sci
; 13(4): 271-6, 2016.
Artículo
en Inglés
| MEDLINE | ID: mdl-27076783
11.
Population pharmacokinetic modelling and simulation of 5-fluorouracil incorporating a circadian rhythm in rats.
Xenobiotica
; 46(7): 597-604, 2016 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-26503235
12.
A validated LC-MS/MS method for the determination of canagliflozin, a sodium-glucose co-transporter 2 (SGLT-2) inhibitor, in a lower volume of rat plasma: application to pharmacokinetic studies in rats.
Biomed Chromatogr
; 30(10): 1549-55, 2016 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-26989857
13.
Semi-physiological pharmacokinetic-pharmacodynamic (PK-PD) modeling and simulation of 5-fluorouracil for thrombocytopenia in rats.
Xenobiotica
; 45(1): 19-28, 2015 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-25050790
14.
Application of dissolving microneedles to glucose monitoring through dermal interstitial fluid.
Biol Pharm Bull
; 37(11): 1776-81, 2014.
Artículo
en Inglés
| MEDLINE | ID: mdl-25366483
15.
Semi-physiological pharmacokinetic-pharmacodynamic modeling and simulation of 5-fluorouracil for the whole time course of alterations in leukocyte, neutrophil and lymphocyte counts in rats.
Xenobiotica
; 44(9): 804-18, 2014 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-24650147
16.
Pharmacokinetic-toxicodynamic Modeling to Elucidate the Involvement of Dorsal Root Ganglion Neuron in Oxaliplatin-induced Peripheral Neuropathy.
Anticancer Res
; 44(2): 575-584, 2024 Feb.
Artículo
en Inglés
| MEDLINE | ID: mdl-38307592
17.
Translational PK-PD/TD modeling of antitumor effects and peripheral neuropathy in gemcitabine and nab-paclitaxel chemotherapy from xenograft mice to patients for optimal dose and schedule.
Cancer Chemother Pharmacol
; 93(4): 365-379, 2024 Apr.
Artículo
en Inglés
| MEDLINE | ID: mdl-38117301
18.
Pre-therapeutic assessment of plasma dihydrouracil/uracil ratio for predicting the pharmacokinetic parameters of 5-fluorouracil and tumor growth in a rat model of colorectal cancer.
Biol Pharm Bull
; 36(6): 907-16, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23575271
19.
A predictive biomarker for altered 5-fluorouracil pharmacokinetics following repeated administration in a rat model of colorectal cancer.
Biopharm Drug Dispos
; 34(7): 365-76, 2013 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-23836081
20.
Pharmacokinetics of 5-fluorouracil and increased hepatic dihydropyrimidine dehydrogenase activity levels in 1,2-dimethylhydrazine-induced colorectal cancer model rats.
Eur J Drug Metab Pharmacokinet
; 38(3): 171-81, 2013 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-23197286