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1.
Synthetic flavonoid derivatives targeting the glycogen phosphorylase inhibitor site: QM/MM-PBSA motivated synthesis of substituted 5,7-dihydroxyflavones, crystallography, in vitro kinetics and ex-vivo cellular experiments reveal novel potent inhibitors.
Bioorg Chem
; 102: 104003, 2020 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-32771768
2.
High Consistency of Structure-Based Design and X-Ray Crystallography: Design, Synthesis, Kinetic Evaluation and Crystallographic Binding Mode Determination of Biphenyl-N-acyl-ß-d-Glucopyranosylamines as Glycogen Phosphorylase Inhibitors.
Molecules
; 24(7)2019 Apr 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-30987252
3.
Multidisciplinary docking, kinetics and X-ray crystallography studies of baicalein acting as a glycogen phosphorylase inhibitor and determination of its' potential against glioblastoma in cellular models.
Chem Biol Interact
; 382: 110568, 2023 Sep 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37277066
4.
Affinity Crystallography Reveals Binding of Pomegranate Juice Anthocyanins at the Inhibitor Site of Glycogen Phosphorylase: The Contribution of a Sugar Moiety to Potency and Its Implications to the Binding Mode.
J Agric Food Chem
; 68(37): 10191-10199, 2020 Sep 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-32840370
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