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1.

Laboratory evolution reveals general and specific tolerance mechanisms for commodity chemicals.

Lennen, Rebecca M; Lim, Hyun Gyu; Jensen, Kristian; Mohammed, Elsayed T; Phaneuf, Patrick V; Noh, Myung Hyun; Malla, Sailesh; Börner, Rosa A; Chekina, Ksenia; Özdemir, Emre; Bonde, Ida; Koza, Anna; Maury, Jérôme; Pedersen, Lasse E; Schöning, Lars Y; Sonnenschein, Nikolaus; Palsson, Bernhard O; Nielsen, Alex T; Sommer, Morten O A; Herrgård, Markus J; Feist, Adam M.

Metab Eng ; 76: 179-192, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36738854

2.

Genome-wide identification of tolerance mechanisms toward p-coumaric acid in Pseudomonas putida.

Calero, Patricia; Jensen, Sheila I; Bojanovic, Klara; Lennen, Rebecca M; Koza, Anna; Nielsen, Alex T.

Biotechnol Bioeng ; 115(3): 762-774, 2018 03.

Artículo en Inglés | MEDLINE | ID: mdl-29131301

3.

Transient overexpression of DNA adenine methylase enables efficient and mobile genome engineering with reduced off-target effects.

Lennen, Rebecca M; Nilsson Wallin, Annika I; Pedersen, Margit; Bonde, Mads; Luo, Hao; Herrgård, Markus J; Sommer, Morten O A.

Nucleic Acids Res ; 44(4): e36, 2016 Feb 29.

Artículo en Inglés | MEDLINE | ID: mdl-26496947

4.

Generation of a platform strain for ionic liquid tolerance using adaptive laboratory evolution.

Mohamed, Elsayed T; Wang, Shizeng; Lennen, Rebecca M; Herrgård, Markus J; Simmons, Blake A; Singer, Steven W; Feist, Adam M.

Microb Cell Fact ; 16(1): 204, 2017 Nov 16.

Artículo en Inglés | MEDLINE | ID: mdl-29145855

5.

Genome-wide Escherichia coli stress response and improved tolerance towards industrially relevant chemicals.

Rau, Martin Holm; Calero, Patricia; Lennen, Rebecca M; Long, Katherine S; Nielsen, Alex T.

Microb Cell Fact ; 15(1): 176, 2016 Oct 13.

Artículo en Inglés | MEDLINE | ID: mdl-27737709

6.

Combinatorial strategies for improving multiple-stress resistance in industrially relevant Escherichia coli strains.

Lennen, Rebecca M; Herrgård, Markus J.

Appl Environ Microbiol ; 80(19): 6223-42, 2014 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-25085490

7.

Identification of transport proteins involved in free fatty acid efflux in Escherichia coli.

Lennen, Rebecca M; Politz, Mark G; Kruziki, Max A; Pfleger, Brian F.

J Bacteriol ; 195(1): 135-44, 2013 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-23104810

8.

Kinetic modeling of free fatty acid production in Escherichia coli based on continuous cultivation of a plasmid free strain.

Youngquist, J Tyler; Lennen, Rebecca M; Ranatunga, Don R; Bothfeld, William H; Marner, Wesley D; Pfleger, Brian F.

Biotechnol Bioeng ; 109(6): 1518-27, 2012 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-22234725

9.

Membrane stresses induced by overproduction of free fatty acids in Escherichia coli.

Lennen, Rebecca M; Kruziki, Max A; Kumar, Kritika; Zinkel, Robert A; Burnum, Kristin E; Lipton, Mary S; Hoover, Spencer W; Ranatunga, Don R; Wittkopp, Tyler M; Marner, Wesley D; Pfleger, Brian F.

Appl Environ Microbiol ; 77(22): 8114-28, 2011 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-21948837

10.

Bacterial production of free fatty acids from freshwater macroalgal cellulose.

Hoover, Spencer W; Marner, Wesley D; Brownson, Amy K; Lennen, Rebecca M; Wittkopp, Tyler M; Yoshitani, Jun; Zulkifly, Shahrizim; Graham, Linda E; Chaston, Sheena D; McMahon, Katherine D; Pfleger, Brian F.

Appl Microbiol Biotechnol ; 91(2): 435-46, 2011 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-21643704

11.

Escherichia coli Data-Driven Strain Design Using Aggregated Adaptive Laboratory Evolution Mutational Data.

Phaneuf, Patrick V; Zielinski, Daniel C; Yurkovich, James T; Johnsen, Josefin; Szubin, Richard; Yang, Lei; Kim, Se Hyeuk; Schulz, Sebastian; Wu, Muyao; Dalldorf, Christopher; Ozdemir, Emre; Lennen, Rebecca M; Palsson, Bernhard O; Feist, Adam M.

ACS Synth Biol ; 10(12): 3379-3395, 2021 12 17.

Artículo en Inglés | MEDLINE | ID: mdl-34762392

12.

A process for microbial hydrocarbon synthesis: Overproduction of fatty acids in Escherichia coli and catalytic conversion to alkanes.

Lennen, Rebecca M; Braden, Drew J; West, Ryan A; Dumesic, James A; Pfleger, Brian F.

Biotechnol Bioeng ; 106(2): 193-202, 2010 Jun 01.

Artículo en Inglés | MEDLINE | ID: mdl-20073090

13.

Systems biology solutions for biochemical production challenges.

Hansen, Anne Sofie Lærke; Lennen, Rebecca M; Sonnenschein, Nikolaus; Herrgård, Markus J.

Curr Opin Biotechnol ; 45: 85-91, 2017 06.

Artículo en Inglés | MEDLINE | ID: mdl-28319856

14.

Seven gene deletions in seven days: Fast generation of Escherichia coli strains tolerant to acetate and osmotic stress.

Jensen, Sheila I; Lennen, Rebecca M; Herrgård, Markus J; Nielsen, Alex T.

Sci Rep ; 5: 17874, 2015 Dec 08.

Artículo en Inglés | MEDLINE | ID: mdl-26643270

15.

Microbial production of fatty acid-derived fuels and chemicals.

Lennen, Rebecca M; Pfleger, Brian F.

Curr Opin Biotechnol ; 24(6): 1044-53, 2013 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-23541503

16.

Modulating membrane composition alters free fatty acid tolerance in Escherichia coli.

Lennen, Rebecca M; Pfleger, Brian F.

PLoS One ; 8(1): e54031, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-23349781

17.

Engineering Escherichia coli to synthesize free fatty acids.

Lennen, Rebecca M; Pfleger, Brian F.

Trends Biotechnol ; 30(12): 659-67, 2012 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-23102412

18.

Isolation of improved free fatty acid overproducing strains of Escherichia coli via Nile red based high-throughput screening.

Hoover, Spencer W; Youngquist, J Tyler; Angart, Phil A; Withers, Sydnor T; Lennen, Rebecca M; Pfleger, Brian F.

Environ Prog Sustain Energy ; 31(1): 17-23, 2012 Apr.

Artículo en Inglés | MEDLINE | ID: mdl-30034576

19.

BIOTECHNOLOGY. Benefits of selective feeding.

Lennen, Rebecca M.

Science ; 353(6299): 542-3, 2016 Aug 05.

Artículo en Inglés | MEDLINE | ID: mdl-27493169

20.

Non-chemical biofouling control in heat exchangers and seawater piping systems using acoustic pulses generated by an electrical discharge.

Brizzolara, Robert A; Nordham, David J; Walch, Marianne; Lennen, Rebecca M; Simmons, Ron; Burnett, Evan; Mazzola, Michael S.

Biofouling ; 19(1): 19-35, 2003 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-14618686

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Laboratory evolution reveals general and specific tolerance mechanisms for commodity chemicals.

Genome-wide identification of tolerance mechanisms toward p-coumaric acid in Pseudomonas putida.

Transient overexpression of DNA adenine methylase enables efficient and mobile genome engineering with reduced off-target effects.

Generation of a platform strain for ionic liquid tolerance using adaptive laboratory evolution.

Genome-wide Escherichia coli stress response and improved tolerance towards industrially relevant chemicals.

Combinatorial strategies for improving multiple-stress resistance in industrially relevant Escherichia coli strains.

Identification of transport proteins involved in free fatty acid efflux in Escherichia coli.

Kinetic modeling of free fatty acid production in Escherichia coli based on continuous cultivation of a plasmid free strain.

Membrane stresses induced by overproduction of free fatty acids in Escherichia coli.

Bacterial production of free fatty acids from freshwater macroalgal cellulose.

Escherichia coli Data-Driven Strain Design Using Aggregated Adaptive Laboratory Evolution Mutational Data.

A process for microbial hydrocarbon synthesis: Overproduction of fatty acids in Escherichia coli and catalytic conversion to alkanes.

Systems biology solutions for biochemical production challenges.

Seven gene deletions in seven days: Fast generation of Escherichia coli strains tolerant to acetate and osmotic stress.

Microbial production of fatty acid-derived fuels and chemicals.

Modulating membrane composition alters free fatty acid tolerance in Escherichia coli.

Engineering Escherichia coli to synthesize free fatty acids.

Isolation of improved free fatty acid overproducing strains of Escherichia coli via Nile red based high-throughput screening.

BIOTECHNOLOGY. Benefits of selective feeding.

Non-chemical biofouling control in heat exchangers and seawater piping systems using acoustic pulses generated by an electrical discharge.