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1.

Organoid Modeling of the Tumor Immune Microenvironment.

Neal, James T; Li, Xingnan; Zhu, Junjie; Giangarra, Valeria; Grzeskowiak, Caitlin L; Ju, Jihang; Liu, Iris H; Chiou, Shin-Heng; Salahudeen, Ameen A; Smith, Amber R; Deutsch, Brian C; Liao, Lillian; Zemek, Allison J; Zhao, Fan; Karlsson, Kasper; Schultz, Liora M; Metzner, Thomas J; Nadauld, Lincoln D; Tseng, Yuen-Yi; Alkhairy, Sahar; Oh, Coyin; Keskula, Paula; Mendoza-Villanueva, Daniel; De La Vega, Francisco M; Kunz, Pamela L; Liao, Joseph C; Leppert, John T; Sunwoo, John B; Sabatti, Chiara; Boehm, Jesse S; Hahn, William C; Zheng, Grace X Y; Davis, Mark M; Kuo, Calvin J.

Cell ; 175(7): 1972-1988.e16, 2018 12 13.

Artículo en Inglés | MEDLINE | ID: mdl-30550791

2.

Recurrent repeat expansions in human cancer genomes.

Erwin, Graham S; Gürsoy, Gamze; Al-Abri, Rashid; Suriyaprakash, Ashwini; Dolzhenko, Egor; Zhu, Kevin; Hoerner, Christian R; White, Shannon M; Ramirez, Lucia; Vadlakonda, Ananya; Vadlakonda, Alekhya; von Kraut, Konor; Park, Julia; Brannon, Charlotte M; Sumano, Daniel A; Kirtikar, Raushun A; Erwin, Alicia A; Metzner, Thomas J; Yuen, Ryan K C; Fan, Alice C; Leppert, John T; Eberle, Michael A; Gerstein, Mark; Snyder, Michael P.

Nature ; 613(7942): 96-102, 2023 01.

Artículo en Inglés | MEDLINE | ID: mdl-36517591

3.

Detecting androgen receptor (AR), AR variant 7 (AR-V7), prostate-specific membrane antigen (PSMA), and prostate-specific antigen (PSA) gene expression in CTCs and plasma exosome-derived cfRNA in patients with metastatic castration-resistant prostate cancer (mCRPC) by integrating the VTX-1 CTC isolation system with the QIAGEN AdnaTest.

Liu, Haiyan E; Vuppalapaty, Meghah; Hoerner, Christian R; Bergstrom, Colin P; Chiu, Michael; Lemaire, Clementine; Che, James; Kaur, Amanpreet; Dimmick, Adam; Liu, Sean; Metzner, Thomas J; Araya, Menna; Crouse, Steve; Sprenger-Haussels, Markus; Schlumpberger, Martin; Leppert, John T; Hauch, Siegfried; Sollier, Elodie; Fan, Alice C.

BMC Cancer ; 24(1): 482, 2024 Apr 16.

Artículo en Inglés | MEDLINE | ID: mdl-38627648

4.

Nanoparticle-enabled innate immune stimulation activates endogenous tumor-infiltrating T cells with broad antigen specificities.

Yin, Qian; Yu, Wong; Grzeskowiak, Caitlin L; Li, Jing; Huang, Huang; Guo, Jing; Chen, Liang; Wang, Feng; Zhao, Fan; von Boehmer, Lotta; Metzner, Thomas J; Leppert, John T; Chien, Yueh-Hsiu; Kuo, Calvin J; Davis, Mark M.

Proc Natl Acad Sci U S A ; 118(21)2021 05 25.

Artículo en Inglés | MEDLINE | ID: mdl-34021082

5.

The m⁶A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor.

Xiao, Yiren; Thakkar, Kaushik N; Zhao, Hongjuan; Broughton, James; Li, Yang; Seoane, Jose A; Diep, Anh N; Metzner, Thomas J; von Eyben, Rie; Dill, David L; Brooks, James D; Curtis, Christina; Leppert, John T; Ye, Jiangbin; Peehl, Donna M; Giaccia, Amato J; Sinha, Subarna; Rankin, Erinn B.

Proc Natl Acad Sci U S A ; 117(35): 21441-21449, 2020 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-32817424

6.

Cytometric comparisons between circulating tumor cells from prostate cancer patients and the prostate-tumor-derived LNCaP cell line.

Lazar, Daniel C; Cho, Edward H; Luttgen, Madelyn S; Metzner, Thomas J; Uson, Maria Loressa; Torrey, Melissa; Gross, Mitchell E; Kuhn, Peter.

Phys Biol ; 9(1): 016002, 2012 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-22306736

7.

Clinical laboratory tests associated with survival in patients with metastatic renal cell carcinoma: A Laboratory Wide Association Study (LWAS).

Velaer, Kyla; Thomas, I-Chun; Yang, Jaden; Kapphahn, Kristopher; Metzner, Thomas J; Golla, Abhinav; Hoerner, Christian R; Fan, Alice C; Master, Viraj; Chertow, Glenn M; Brooks, James D; Patel, Chirag J; Desai, Manisha; Leppert, John T.

Urol Oncol ; 40(1): 12.e23-12.e30, 2022 01.

Artículo en Inglés | MEDLINE | ID: mdl-34580027

8.

Development of a DNA Methylation-Based Diagnostic Signature to Distinguish Benign Oncocytoma From Renal Cell Carcinoma.

Brennan, Kevin; Metzner, Thomas J; Kao, Chia-Sui; Massie, Charlie E; Stewart, Grant D; Haile, Robert W; Brooks, James D; Hitchins, Megan P; Leppert, John T; Gevaert, Olivier.

JCO Precis Oncol ; 42020.

Artículo en Inglés | MEDLINE | ID: mdl-33015531

9.

Multiregion Quantification of Extracellular Signal-regulated Kinase Activity in Renal Cell Carcinoma.

Hoerner, Christian R; Massoudi, Rustin; Metzner, Thomas J; Stell, Laurel; O'Rourke, Jennifer J; Kong, Christina S; Liliental, Joanna E; Brooks, James D; Sabatti, Chiara; Leppert, John T; Fan, Alice C.

Eur Urol Oncol ; 3(3): 360-364, 2020 06.

Artículo en Inglés | MEDLINE | ID: mdl-31412000

10.

The Harms of Overdiagnosis and Overtreatment in Patients with Small Renal Masses: A Mini-review.

Sohlberg, Ericka M; Metzner, Thomas J; Leppert, John T.

Eur Urol Focus ; 5(6): 943-945, 2019 Nov.

Artículo en Inglés | MEDLINE | ID: mdl-30905599

11.

Early Changes in CT Perfusion Parameters: Primary Renal Carcinoma Versus Metastases After Treatment with Targeted Therapy.

Fan, Alice C; Sundaram, Vandana; Kino, Aya; Schmiedeskamp, Heiko; Metzner, Thomas J; Kamaya, Aya.

Cancers (Basel) ; 11(5)2019 04 30.

Artículo en Inglés | MEDLINE | ID: mdl-31052289

12.

Optical biopsy of penile cancer with in vivo confocal laser endomicroscopy.

Shkolyar, Eugene; Laurie, Mark A; Mach, Kathleen E; Trivedi, Dharati R; Zlatev, Dimitar V; Chang, Timothy C; Metzner, Thomas J; Leppert, John T; Kao, Chia-Sui; Liao, Joseph C.

Urol Oncol ; 37(11): 809.e1-809.e8, 2019 11.

Artículo en Inglés | MEDLINE | ID: mdl-31537485

13.

Surface-Enhanced Raman Scattering Nanoparticles for Multiplexed Imaging of Bladder Cancer Tissue Permeability and Molecular Phenotype.

Davis, Ryan M; Kiss, Bernhard; Trivedi, Dharati R; Metzner, Thomas J; Liao, Joseph C; Gambhir, Sanjiv S.

ACS Nano ; 12(10): 9669-9679, 2018 10 23.

Artículo en Inglés | MEDLINE | ID: mdl-30203645

14.

Preclinical Testing of a Combination Stone Basket and Ureteral Balloon to Extract Ureteral Stones.

Massoudi, Rustin; Metzner, Thomas J; Bonneau, Buzz; Ngo, Tin C; Shinghal, Rajesh; Leppert, John T.

J Endourol ; 32(2): 96-99, 2018 02.

Artículo en Inglés | MEDLINE | ID: mdl-29216731

15.

Monitoring Neutropenia for Cancer Patients at the Point of Care.

Inan, Hakan; Kingsley, James L; Ozen, Mehmet O; Tekin, Huseyin Cumhur; Hoerner, Christian R; Imae, Yoriko; Metzner, Thomas J; Preiss, Jordan S; Durmus, Naside Gozde; Ozsoz, Mehmet; Wakelee, Heather; Fan, Alice C; Tüzel, Erkan; Demirci, Utkan.

Small Methods ; 1(9)2017 Sep 11.

Artículo en Inglés | MEDLINE | ID: mdl-30740513

16.

Endoscopic molecular imaging of human bladder cancer using a CD47 antibody.

Pan, Ying; Volkmer, Jens-Peter; Mach, Kathleen E; Rouse, Robert V; Liu, Jen-Jane; Sahoo, Debashis; Chang, Timothy C; Metzner, Thomas J; Kang, Lei; van de Rijn, Matt; Skinner, Eila C; Gambhir, Sanjiv S; Weissman, Irving L; Liao, Joseph C.

Sci Transl Med ; 6(260): 260ra148, 2014 Oct 29.

Artículo en Inglés | MEDLINE | ID: mdl-25355698

17.

Editorial Comment.

Metzner, Thomas J; Leppert, John T.

Urology ; 100: 156-157, 2017 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-27988153

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