Búsqueda | Portal de Búsqueda de la BVS Enfermería

1.

Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology.

Sies, Helmut; Belousov, Vsevolod V; Chandel, Navdeep S; Davies, Michael J; Jones, Dean P; Mann, Giovanni E; Murphy, Michael P; Yamamoto, Masayuki; Winterbourn, Christine.

Nat Rev Mol Cell Biol ; 23(7): 499-515, 2022 07.

Artículo en Inglés | MEDLINE | ID: mdl-35190722

2.

Krebs Cycle Reimagined: The Emerging Roles of Succinate and Itaconate as Signal Transducers.

Murphy, Michael P; O'Neill, Luke A J.

Cell ; 174(4): 780-784, 2018 08 09.

Artículo en Inglés | MEDLINE | ID: mdl-30096309

3.

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.

Mills, Evanna L; Kelly, Beth; Logan, Angela; Costa, Ana S H; Varma, Mukund; Bryant, Clare E; Tourlomousis, Panagiotis; Däbritz, J Henry M; Gottlieb, Eyal; Latorre, Isabel; Corr, Sinéad C; McManus, Gavin; Ryan, Dylan; Jacobs, Howard T; Szibor, Marten; Xavier, Ramnik J; Braun, Thomas; Frezza, Christian; Murphy, Michael P; O'Neill, Luke A.

Cell ; 167(2): 457-470.e13, 2016 Oct 06.

Artículo en Inglés | MEDLINE | ID: mdl-27667687

4.

A break in mitochondrial endosymbiosis as a basis for inflammatory diseases.

Murphy, Michael P; O'Neill, Luke A J.

Nature ; 626(7998): 271-279, 2024 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-38326590

5.

Macrophage fumarate hydratase restrains mtRNA-mediated interferon production.

Hooftman, Alexander; Peace, Christian G; Ryan, Dylan G; Day, Emily A; Yang, Ming; McGettrick, Anne F; Yin, Maureen; Montano, Erica N; Huo, Lihong; Toller-Kawahisa, Juliana E; Zecchini, Vincent; Ryan, Tristram A J; Bolado-Carrancio, Alfonso; Casey, Alva M; Prag, Hiran A; Costa, Ana S H; De Los Santos, Gabriela; Ishimori, Mariko; Wallace, Daniel J; Venuturupalli, Swamy; Nikitopoulou, Efterpi; Frizzell, Norma; Johansson, Cecilia; Von Kriegsheim, Alexander; Murphy, Michael P; Jefferies, Caroline; Frezza, Christian; O'Neill, Luke A J.

Nature ; 615(7952): 490-498, 2023 03.

Artículo en Inglés | MEDLINE | ID: mdl-36890227

6.

Ubiad1 is an antioxidant enzyme that regulates eNOS activity by CoQ10 synthesis.

Mugoni, Vera; Postel, Ruben; Catanzaro, Valeria; De Luca, Elisa; Turco, Emilia; Digilio, Giuseppe; Silengo, Lorenzo; Murphy, Michael P; Medana, Claudio; Stainier, Didier Y R; Bakkers, Jeroen; Santoro, Massimo M.

Cell ; 152(3): 504-18, 2013 Jan 31.

Artículo en Inglés | MEDLINE | ID: mdl-23374346

7.

KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation.

Pearce, Laura R; Atanassova, Neli; Banton, Matthew C; Bottomley, Bill; van der Klaauw, Agatha A; Revelli, Jean-Pierre; Hendricks, Audrey; Keogh, Julia M; Henning, Elana; Doree, Deon; Jeter-Jones, Sabrina; Garg, Sumedha; Bochukova, Elena G; Bounds, Rebecca; Ashford, Sofie; Gayton, Emma; Hindmarsh, Peter C; Shield, Julian P H; Crowne, Elizabeth; Barford, David; Wareham, Nick J; O'Rahilly, Stephen; Murphy, Michael P; Powell, David R; Barroso, Ines; Farooqi, I Sadaf.

Cell ; 155(4): 765-77, 2013 Nov 07.

Artículo en Inglés | MEDLINE | ID: mdl-24209692

8.

How should we talk about metabolism?

Murphy, Michael P; O'Neill, Luke A J.

Nat Immunol ; 21(7): 713-715, 2020 07.

Artículo en Inglés | MEDLINE | ID: mdl-32409776

9.

DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88.

Tarallo, Valeria; Hirano, Yoshio; Gelfand, Bradley D; Dridi, Sami; Kerur, Nagaraj; Kim, Younghee; Cho, Won Gil; Kaneko, Hiroki; Fowler, Benjamin J; Bogdanovich, Sasha; Albuquerque, Romulo J C; Hauswirth, William W; Chiodo, Vince A; Kugel, Jennifer F; Goodrich, James A; Ponicsan, Steven L; Chaudhuri, Gautam; Murphy, Michael P; Dunaief, Joshua L; Ambati, Balamurali K; Ogura, Yuichiro; Yoo, Jae Wook; Lee, Dong-ki; Provost, Patrick; Hinton, David R; Núñez, Gabriel; Baffi, Judit Z; Kleinman, Mark E; Ambati, Jayakrishna.

Cell ; 149(4): 847-59, 2012 May 11.

Artículo en Inglés | MEDLINE | ID: mdl-22541070

10.

Rerouting metabolism to activate macrophages.

Murphy, Michael P.

Nat Immunol ; 20(9): 1097-1099, 2019 09.

Artículo en Inglés | MEDLINE | ID: mdl-31384059

11.

ABCG2-Expressing Clonal Repopulating Endothelial Cells Serve to Form and Maintain Blood Vessels.

Lin, Yang; Gil, Chang-Hyun; Banno, Kimihiko; Yokoyama, Masataka; Wingo, Matthew; Go, Ellen; Prasain, Nutan; Liu, Ying; Hato, Takashi; Naito, Hisamichi; Wakabayashi, Taku; Sominskaia, Musia; Gao, Meng; Chen, Kevin; Geng, Fuqiang; Gomez Salinero, Jesus Maria; Chen, Sisi; Shelley, W Christopher; Yoshimoto, Momoko; Li Calzi, Sergio; Murphy, Michael P; Horie, Kyoji; Grant, Maria B; Schreiner, Ryan; Redmond, David; Basile, David P; Rafii, Shahin; Yoder, Mervin C.

Circulation ; 2024 Apr 29.

Artículo en Inglés | MEDLINE | ID: mdl-38682338

12.

AICAR confers prophylactic cardioprotection in doxorubicin-induced heart failure in rats.

Choksey, Anurag; Carter, Ryan D; Thackray, Benjamin D; Ball, Vicky; Kennedy, Brett W C; Ha, Lea Hong Tuan; Sharma, Eshita; Broxholme, John; Castro-Guarda, Marcos; Murphy, Michael P; Heather, Lisa C; Tyler, Damian J; Timm, Kerstin N.

J Mol Cell Cardiol ; 191: 12-22, 2024 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-38643934

13.

In vivo mitochondria-targeted protection against uterine artery vascular dysfunction and remodelling in rodent hypoxic pregnancy.

Wang, Zhongchao; Camm, Emily J; Nuzzo, Anna Maria; Spiroski, Ana-Mishel; Skeffington, Katie L; Ashmore, Thomas J; Rolfo, Alessandro; Todros, Tullia; Logan, Angela; Ma, Jin; Murphy, Michael P; Niu, Youguo; Giussani, Dino A.

J Physiol ; 602(6): 1211-1225, 2024 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-38381050

14.

Predictors of Prolonged Length of Stay after Elective Carotid Revascularization.

Aridi, Hanaa; Leon, Brandon; Murphy, Michael P; Malas, Mahmoud; Schermerhorn, Marc; Kashyap, Vikram S; Wang, Grace; Eldrup-Jorgensen, Jens; Gonzalez, Andrew; Motaganahalli, Raghu.

J Vasc Surg ; 2024 May 17.

Artículo en Inglés | MEDLINE | ID: mdl-38763455

15.

Why succinate? Physiological regulation by a mitochondrial coenzyme Q sentinel.

Murphy, Michael P; Chouchani, Edward T.

Nat Chem Biol ; 18(5): 461-469, 2022 05.

Artículo en Inglés | MEDLINE | ID: mdl-35484255

16.

Generation of mitochondrial reactive oxygen species is controlled by ATPase inhibitory factor 1 and regulates cognition.

Esparza-Moltó, Pau B; Romero-Carramiñana, Inés; Núñez de Arenas, Cristina; Pereira, Marta P; Blanco, Noelia; Pardo, Beatriz; Bates, Georgina R; Sánchez-Castillo, Carla; Artuch, Rafael; Murphy, Michael P; Esteban, José A; Cuezva, José M.

PLoS Biol ; 19(5): e3001252, 2021 05.

Artículo en Inglés | MEDLINE | ID: mdl-33983919

17.

Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury.

Prag, Hiran A; Aksentijevic, Dunja; Dannhorn, Andreas; Giles, Abigail V; Mulvey, John F; Sauchanka, Olga; Du, Luping; Bates, Georgina; Reinhold, Johannes; Kula-Alwar, Duvaraka; Xu, Zhelong; Pellerin, Luc; Goodwin, Richard J A; Murphy, Michael P; Krieg, Thomas.

Circ Res ; 131(6): 528-541, 2022 09 02.

Artículo en Inglés | MEDLINE | ID: mdl-35959683

18.

Human mitochondrial glutathione transferases: Kinetic parameters and accommodation of a mitochondria-targeting group in substrates.

Cardwell, Patrick A; Del Moro, Carlo; Murphy, Michael P; Lapthorn, Adrian J; Hartley, Richard C.

Bioorg Med Chem ; 104: 117712, 2024 Apr 15.

Artículo en Inglés | MEDLINE | ID: mdl-38593670

19.

Accumulation of succinate controls activation of adipose tissue thermogenesis.

Mills, Evanna L; Pierce, Kerry A; Jedrychowski, Mark P; Garrity, Ryan; Winther, Sally; Vidoni, Sara; Yoneshiro, Takeshi; Spinelli, Jessica B; Lu, Gina Z; Kazak, Lawrence; Banks, Alexander S; Haigis, Marcia C; Kajimura, Shingo; Murphy, Michael P; Gygi, Steven P; Clish, Clary B; Chouchani, Edward T.

Nature ; 560(7716): 102-106, 2018 08.

Artículo en Inglés | MEDLINE | ID: mdl-30022159

20.

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

Mills, Evanna L; Ryan, Dylan G; Prag, Hiran A; Dikovskaya, Dina; Menon, Deepthi; Zaslona, Zbigniew; Jedrychowski, Mark P; Costa, Ana S H; Higgins, Maureen; Hams, Emily; Szpyt, John; Runtsch, Marah C; King, Martin S; McGouran, Joanna F; Fischer, Roman; Kessler, Benedikt M; McGettrick, Anne F; Hughes, Mark M; Carroll, Richard G; Booty, Lee M; Knatko, Elena V; Meakin, Paul J; Ashford, Michael L J; Modis, Louise K; Brunori, Gino; Sévin, Daniel C; Fallon, Padraic G; Caldwell, Stuart T; Kunji, Edmund R S; Chouchani, Edward T; Frezza, Christian; Dinkova-Kostova, Albena T; Hartley, Richard C; Murphy, Michael P; O'Neill, Luke A.

Nature ; 556(7699): 113-117, 2018 04 05.

Artículo en Inglés | MEDLINE | ID: mdl-29590092

Portal de Búsqueda de la BVS Enfermería

Información y Conocimiento para la Salud

Configurar filtros

Su selección (0)

Formato de exportación:

Exportar:

Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology.

Krebs Cycle Reimagined: The Emerging Roles of Succinate and Itaconate as Signal Transducers.

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.

A break in mitochondrial endosymbiosis as a basis for inflammatory diseases.

Macrophage fumarate hydratase restrains mtRNA-mediated interferon production.

Ubiad1 is an antioxidant enzyme that regulates eNOS activity by CoQ10 synthesis.

KSR2 mutations are associated with obesity, insulin resistance, and impaired cellular fuel oxidation.

How should we talk about metabolism?

DICER1 loss and Alu RNA induce age-related macular degeneration via the NLRP3 inflammasome and MyD88.

Rerouting metabolism to activate macrophages.

ABCG2-Expressing Clonal Repopulating Endothelial Cells Serve to Form and Maintain Blood Vessels.

AICAR confers prophylactic cardioprotection in doxorubicin-induced heart failure in rats.

In vivo mitochondria-targeted protection against uterine artery vascular dysfunction and remodelling in rodent hypoxic pregnancy.

Predictors of Prolonged Length of Stay after Elective Carotid Revascularization.

Why succinate? Physiological regulation by a mitochondrial coenzyme Q sentinel.

Generation of mitochondrial reactive oxygen species is controlled by ATPase inhibitory factor 1 and regulates cognition.

Ischemia-Selective Cardioprotection by Malonate for Ischemia/Reperfusion Injury.

Human mitochondrial glutathione transferases: Kinetic parameters and accommodation of a mitochondria-targeting group in substrates.

Accumulation of succinate controls activation of adipose tissue thermogenesis.

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.