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1.

B cells regulate hematopoietic stem cells via cholinergic signaling.

Patel, Sweta B; Pietras, Eric M.

Nat Immunol ; 23(4): 476-478, 2022 04.

Artículo en Inglés | MEDLINE | ID: mdl-35347284

2.

Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion.

Tengesdal, Isak W; Menon, Dinoop R; Osborne, Douglas G; Neff, Charles P; Powers, Nicholas E; Gamboni, Fabia; Mauro, Adolfo G; D'Alessandro, Angelo; Stefanoni, Davide; Henen, Morkos A; Mills, Taylor S; De Graaf, Dennis M; Azam, Tania; Vogeli, Beat; Palmer, Brent E; Pietras, Eric M; DeGregori, James; Tan, Aik-Choon; Joosten, Leo A B; Fujita, Mayumi; Dinarello, Charles A; Marchetti, Carlo.

Proc Natl Acad Sci U S A ; 118(10)2021 03 09.

Artículo en Inglés | MEDLINE | ID: mdl-33649199

3.

Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.

Hérault, Aurélie; Binnewies, Mikhail; Leong, Stephanie; Calero-Nieto, Fernando J; Zhang, Si Yi; Kang, Yoon-A; Wang, Xiaonan; Pietras, Eric M; Chu, S Haihua; Barry-Holson, Keegan; Armstrong, Scott; Göttgens, Berthold; Passegué, Emmanuelle.

Nature ; 544(7648): 53-58, 2017 04 06.

Artículo en Inglés | MEDLINE | ID: mdl-28355185

4.

TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging.

Davizon-Castillo, Pavel; McMahon, Brandon; Aguila, Sonia; Bark, David; Ashworth, Katrina; Allawzi, Ayed; Campbell, Robert A; Montenont, Emilie; Nemkov, Travis; D'Alessandro, Angelo; Clendenen, Nathan; Shih, Lauren; Sanders, Natalie A; Higa, Kelly; Cox, Allaura; Padilla-Romo, Zavelia; Hernandez, Giovanni; Wartchow, Eric; Trahan, George D; Nozik-Grayck, Eva; Jones, Kenneth; Pietras, Eric M; DeGregori, James; Rondina, Matthew T; Di Paola, Jorge.

Blood ; 134(9): 727-740, 2019 08 29.

Artículo en Inglés | MEDLINE | ID: mdl-31311815

5.

Young bugs rejuvenate old blood.

Pietras, Eric M.

Blood ; 141(14): 1650-1652, 2023 04 06.

Artículo en Inglés | MEDLINE | ID: mdl-37022735

6.

Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis.

Hernandez, Giovanny; Mills, Taylor S; Rabe, Jennifer L; Chavez, James S; Kuldanek, Susan; Kirkpatrick, Gregory; Noetzli, Leila; Jubair, Widian K; Zanche, Michelle; Myers, Jason R; Stevens, Brett M; Fleenor, Courtney J; Adane, Biniam; Dinarello, Charles A; Ashton, John; Jordan, Craig T; Di Paola, Jorge; Hagman, James R; Holers, V Michael; Kuhn, Kristine A; Pietras, Eric M.

Haematologica ; 105(3): 585-597, 2020 03.

Artículo en Inglés | MEDLINE | ID: mdl-31101752

7.

Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells.

Flach, Johanna; Bakker, Sietske T; Mohrin, Mary; Conroy, Pauline C; Pietras, Eric M; Reynaud, Damien; Alvarez, Silvia; Diolaiti, Morgan E; Ugarte, Fernando; Forsberg, E Camilla; Le Beau, Michelle M; Stohr, Bradley A; Méndez, Juan; Morrison, Ciaran G; Passegué, Emmanuelle.

Nature ; 512(7513): 198-202, 2014 Aug 14.

Artículo en Inglés | MEDLINE | ID: mdl-25079315

8.

Inflammation: a key regulator of hematopoietic stem cell fate in health and disease.

Pietras, Eric M.

Blood ; 130(15): 1693-1698, 2017 10 12.

Artículo en Inglés | MEDLINE | ID: mdl-28874349

9.

ISSLS PRIZE IN BASIC SCIENCE 2017: Intervertebral disc/bone marrow cross-talk with Modic changes.

Dudli, Stefan; Sing, David C; Hu, Serena S; Berven, Sigurd H; Burch, Shane; Deviren, Vedat; Cheng, Ivan; Tay, Bobby K B; Alamin, Todd F; Ith, Ma Agnes Martinez; Pietras, Eric M; Lotz, Jeffrey C.

Eur Spine J ; 26(5): 1362-1373, 2017 05.

Artículo en Inglés | MEDLINE | ID: mdl-28138783

10.

Ezh2 spares KitL from the cutter.

Pietras, Eric M.

Blood ; 131(20): 2180-2181, 2018 05 17.

Artículo en Inglés | MEDLINE | ID: mdl-29773542

11.

Pro-inflammatory cytokines: emerging players regulating HSC function in normal and diseased hematopoiesis.

Mirantes, Cristina; Passegué, Emmanuelle; Pietras, Eric M.

Exp Cell Res ; 329(2): 248-54, 2014 Dec 10.

Artículo en Inglés | MEDLINE | ID: mdl-25149680

12.

The importance of tying up loose (DNA) ends.

Pietras, Eric M.

Blood ; 129(18): 2457-2458, 2017 05 04.

Artículo en Inglés | MEDLINE | ID: mdl-28473409

13.

Myelodysplastic syndrome-associated spliceosome gene mutations enhance innate immune signaling.

Pollyea, Daniel A; Harris, Chelsea; Rabe, Jennifer L; Hedin, Brenna R; De Arras, Lesly; Katz, Sigrid; Wheeler, Emily; Bejar, Rafael; Walter, Matthew J; Jordan, Craig T; Pietras, Eric M; Alper, Scott.

Haematologica ; 104(9): e388-e392, 2019 09.

Artículo en Inglés | MEDLINE | ID: mdl-30846499

14.

Isolating mononuclear cells from fetal bone and liver for metabolic, functional, and immunophenotypic analyses in nonhuman primates.

Nash, Michael J; Dobrinskikh, Evgenia; Wang, Dong; Pietras, Eric M; Janssen, Rachel C; Friedman, Jacob E; Wesolowski, Stephanie R.

STAR Protoc ; 5(1): 102849, 2024 Mar 15.

Artículo en Inglés | MEDLINE | ID: mdl-38324447

15.

Chronic inflammation can transform the fate of normal and mutant hematopoietic stem cells.

Li, Jingjing; Malouf, Camille; Miles, Linde A; Willis, Mara B; Pietras, Eric M; King, Katherine Y.

Exp Hematol ; 127: 8-13, 2023 11.

Artículo en Inglés | MEDLINE | ID: mdl-37647982

16.

PU.1 is required to restrain myelopoiesis during chronic inflammatory stress.

Chavez, James S; Rabe, Jennifer L; Niño, Katia E; Wells, Harrison H; Gessner, Rachel L; Mills, Taylor S; Hernandez, Giovanny; Pietras, Eric M.

Front Cell Dev Biol ; 11: 1204160, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37497478

17.

Neonatal Hepatic Myeloid Progenitors Expand and Propagate Liver Injury in Mice.

Alkhani, Anas; Korsholm, Cathrine; Levy, Claire S; Mohamedaly, Sarah; Duwaerts, Caroline C; Pietras, Eric M; Nijagal, Amar.

J Clin Med ; 12(1)2023 Jan 01.

Artículo en Inglés | MEDLINE | ID: mdl-36615137

18.

Myelodysplastic neoplasm-associated U2AF1 mutations induce host defense defects by compromising neutrophil chemotaxis.

Gurule, Natalia J; Malcolm, Kenneth C; Harris, Chelsea; Knapp, Jennifer R; O'Connor, Brian P; McClendon, Jazalle; Janssen, William J; Lee, Frank Fang Yao; Price, Caitlin; Osaghae-Nosa, Jackson; Wheeler, Emily A; McMahon, Christine M; Pietras, Eric M; Pollyea, Daniel A; Alper, Scott.

Leukemia ; 37(10): 2115-2124, 2023 10.

Artículo en Inglés | MEDLINE | ID: mdl-37591942

19.

Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing.

Mitchell, Carl A; Verovskaya, Evgenia V; Calero-Nieto, Fernando J; Olson, Oakley C; Swann, James W; Wang, Xiaonan; Hérault, Aurélie; Dellorusso, Paul V; Zhang, Si Yi; Svendsen, Arthur Flohr; Pietras, Eric M; Bakker, Sietske T; Ho, Theodore T; Göttgens, Berthold; Passegué, Emmanuelle.

Nat Cell Biol ; 25(1): 30-41, 2023 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-36650381

20.

Maternal diet alters long-term innate immune cell memory in fetal and juvenile hematopoietic stem and progenitor cells in nonhuman primate offspring.

Nash, Michael J; Dobrinskikh, Evgenia; Soderborg, Taylor K; Janssen, Rachel C; Takahashi, Diana L; Dean, Tyler A; Varlamov, Oleg; Hennebold, Jon D; Gannon, Maureen; Aagaard, Kjersti M; McCurdy, Carrie E; Kievit, Paul; Bergman, Bryan C; Jones, Kenneth L; Pietras, Eric M; Wesolowski, Stephanie R; Friedman, Jacob E.

Cell Rep ; 42(4): 112393, 2023 04 25.

Artículo en Inglés | MEDLINE | ID: mdl-37058409

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B cells regulate hematopoietic stem cells via cholinergic signaling.

Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansion.

Myeloid progenitor cluster formation drives emergency and leukaemic myelopoiesis.

TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging.

Young bugs rejuvenate old blood.

Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis.

Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells.

Inflammation: a key regulator of hematopoietic stem cell fate in health and disease.

ISSLS PRIZE IN BASIC SCIENCE 2017: Intervertebral disc/bone marrow cross-talk with Modic changes.

Ezh2 spares KitL from the cutter.

Pro-inflammatory cytokines: emerging players regulating HSC function in normal and diseased hematopoiesis.

The importance of tying up loose (DNA) ends.

Myelodysplastic syndrome-associated spliceosome gene mutations enhance innate immune signaling.

Isolating mononuclear cells from fetal bone and liver for metabolic, functional, and immunophenotypic analyses in nonhuman primates.

Chronic inflammation can transform the fate of normal and mutant hematopoietic stem cells.

PU.1 is required to restrain myelopoiesis during chronic inflammatory stress.

Neonatal Hepatic Myeloid Progenitors Expand and Propagate Liver Injury in Mice.

Myelodysplastic neoplasm-associated U2AF1 mutations induce host defense defects by compromising neutrophil chemotaxis.

Stromal niche inflammation mediated by IL-1 signalling is a targetable driver of haematopoietic ageing.

Maternal diet alters long-term innate immune cell memory in fetal and juvenile hematopoietic stem and progenitor cells in nonhuman primate offspring.