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1.

Lung Cancer: A Wily Genetic Opponent.

Hsu, Peggy P; Shaw, Alice T.

Cell ; 169(5): 777-779, 2017 05 18.

Artículo en Inglés | MEDLINE | ID: mdl-28525750

2.

Therapy-induced APOBEC3A drives evolution of persistent cancer cells.

Isozaki, Hideko; Sakhtemani, Ramin; Abbasi, Ammal; Nikpour, Naveed; Stanzione, Marcello; Oh, Sunwoo; Langenbucher, Adam; Monroe, Susanna; Su, Wenjia; Cabanos, Heidie Frisco; Siddiqui, Faria M; Phan, Nicole; Jalili, Pégah; Timonina, Daria; Bilton, Samantha; Gomez-Caraballo, Maria; Archibald, Hannah L; Nangia, Varuna; Dionne, Kristin; Riley, Amanda; Lawlor, Matthew; Banwait, Mandeep Kaur; Cobb, Rosemary G; Zou, Lee; Dyson, Nicholas J; Ott, Christopher J; Benes, Cyril; Getz, Gad; Chan, Chang S; Shaw, Alice T; Gainor, Justin F; Lin, Jessica J; Sequist, Lecia V; Piotrowska, Zofia; Yeap, Beow Y; Engelman, Jeffrey A; Lee, Jake June-Koo; Maruvka, Yosef E; Buisson, Rémi; Lawrence, Michael S; Hata, Aaron N.

Nature ; 620(7973): 393-401, 2023 Aug.

Artículo en Inglés | MEDLINE | ID: mdl-37407818

3.

First-Line Lorlatinib or Crizotinib in Advanced ALK-Positive Lung Cancer.

Shaw, Alice T; Bauer, Todd M; de Marinis, Filippo; Felip, Enriqueta; Goto, Yasushi; Liu, Geoffrey; Mazieres, Julien; Kim, Dong-Wan; Mok, Tony; Polli, Anna; Thurm, Holger; Calella, Anna M; Peltz, Gerson; Solomon, Benjamin J.

N Engl J Med ; 383(21): 2018-2029, 2020 11 19.

Artículo en Inglés | MEDLINE | ID: mdl-33207094

4.

Plain language summary of the updated results from the CROWN study comparing lorlatinib with crizotinib in people with advanced non-small-cell lung cancer.

Solomon, Benjamin J; Bauer, Todd M; K Mok, Tony S; Liu, Geoffrey; Mazieres, Julien; Marinis, Filippo de; Goto, Yasushi; Kim, Dong-Wan; Wu, Yi-Long; Jassem, Jacek; López, Froylán López; Soo, Ross A; Shaw, Alice T; Polli, Anna; Messina, Rossella; Iadeluca, Laura; Toffalorio, Francesca; Felip, Enriqueta.

Future Oncol ; 19(14): 961-973, 2023 May.

Artículo en Inglés | MEDLINE | ID: mdl-37306090

5.

Plain language summary of the CROWN study comparing lorlatinib with crizotinib for people with untreated non-small cell lung cancer.

Solomon, Benjamin J; Bauer, Todd M; de Marinis, Filippo; Felip, Enriqueta; Goto, Yasushi; Liu, Geoffrey; Mazieres, Julien; Kim, Dong-Wan; Mok, Tony; Polli, Anna; Thurm, Holger; Calella, Anna Maria; Peltz, Gerson; Shaw, Alice T.

Future Oncol ; 17(34): 4649-4656, 2021 Dec 01.

Artículo en Inglés | MEDLINE | ID: mdl-34585621

6.

Entrectinib in patients with advanced or metastatic NTRK fusion-positive solid tumours: integrated analysis of three phase 1-2 trials.

Doebele, Robert C; Drilon, Alexander; Paz-Ares, Luis; Siena, Salvatore; Shaw, Alice T; Farago, Anna F; Blakely, Collin M; Seto, Takashi; Cho, Byung Chul; Tosi, Diego; Besse, Benjamin; Chawla, Sant P; Bazhenova, Lyudmila; Krauss, John C; Chae, Young Kwang; Barve, Minal; Garrido-Laguna, Ignacio; Liu, Stephen V; Conkling, Paul; John, Thomas; Fakih, Marwan; Sigal, Darren; Loong, Herbert H; Buchschacher, Gary L; Garrido, Pilar; Nieva, Jorge; Steuer, Conor; Overbeck, Tobias R; Bowles, Daniel W; Fox, Elizabeth; Riehl, Todd; Chow-Maneval, Edna; Simmons, Brian; Cui, Na; Johnson, Ann; Eng, Susan; Wilson, Timothy R; Demetri, George D.

Lancet Oncol ; 21(2): 271-282, 2020 02.

Artículo en Inglés | MEDLINE | ID: mdl-31838007

7.

Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1-2 trials.

Drilon, Alexander; Siena, Salvatore; Dziadziuszko, Rafal; Barlesi, Fabrice; Krebs, Matthew G; Shaw, Alice T; de Braud, Filippo; Rolfo, Christian; Ahn, Myung-Ju; Wolf, Jürgen; Seto, Takashi; Cho, Byoung Chul; Patel, Manish R; Chiu, Chao-Hua; John, Thomas; Goto, Koichi; Karapetis, Christos S; Arkenau, Hendrick-Tobias; Kim, Sang-We; Ohe, Yuichiro; Li, Yu-Chung; Chae, Young K; Chung, Christine H; Otterson, Gregory A; Murakami, Haruyasu; Lin, Chia-Chi; Tan, Daniel S W; Prenen, Hans; Riehl, Todd; Chow-Maneval, Edna; Simmons, Brian; Cui, Na; Johnson, Ann; Eng, Susan; Wilson, Timothy R; Doebele, Robert C.

Lancet Oncol ; 21(2): 261-270, 2020 02.

Artículo en Inglés | MEDLINE | ID: mdl-31838015

8.

Association between circulating tumor DNA burden and disease burden in patients with ALK-positive lung cancer.

Zhang, Eric W; Dagogo-Jack, Ibiayi; Kuo, Anderson; Rooney, Marguerite M; Shaw, Alice T; Digumarthy, Subba R.

Cancer ; 126(20): 4473-4484, 2020 10 15.

Artículo en Inglés | MEDLINE | ID: mdl-32757294

9.

Alectinib versus Crizotinib in Untreated ALK-Positive Non-Small-Cell Lung Cancer.

Peters, Solange; Camidge, D Ross; Shaw, Alice T; Gadgeel, Shirish; Ahn, Jin S; Kim, Dong-Wan; Ou, Sai-Hong I; Pérol, Maurice; Dziadziuszko, Rafal; Rosell, Rafael; Zeaiter, Ali; Mitry, Emmanuel; Golding, Sophie; Balas, Bogdana; Noe, Johannes; Morcos, Peter N; Mok, Tony.

N Engl J Med ; 377(9): 829-838, 2017 08 31.

Artículo en Inglés | MEDLINE | ID: mdl-28586279

10.

Imaging Features and Metastatic Patterns of Advanced ALK-Rearranged Non-Small Cell Lung Cancer.

Mendoza, Dexter P; Lin, Jessica J; Rooney, Marguerite M; Chen, Tianqi; Sequist, Lecia V; Shaw, Alice T; Digumarthy, Subba R.

AJR Am J Roentgenol ; 214(4): 766-774, 2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-31887093

11.

Lorlatinib in advanced ROS1-positive non-small-cell lung cancer: a multicentre, open-label, single-arm, phase 1-2 trial.

Shaw, Alice T; Solomon, Benjamin J; Chiari, Rita; Riely, Gregory J; Besse, Benjamin; Soo, Ross A; Kao, Steven; Lin, Chia-Chi; Bauer, Todd M; Clancy, Jill S; Thurm, Holger; Martini, Jean-Francois; Peltz, Gerson; Abbattista, Antonello; Li, Sherry; Ou, Sai-Hong Ignatius.

Lancet Oncol ; 20(12): 1691-1701, 2019 12.

Artículo en Inglés | MEDLINE | ID: mdl-31669155

12.

Clinical Management of Adverse Events Associated with Lorlatinib.

Bauer, Todd M; Felip, Enriqueta; Solomon, Benjamin J; Thurm, Holger; Peltz, Gerson; Chioda, Marc D; Shaw, Alice T.

Oncologist ; 24(8): 1103-1110, 2019 08.

Artículo en Inglés | MEDLINE | ID: mdl-30890623

13.

Resensitization to Crizotinib by the Lorlatinib ALK Resistance Mutation L1198F.

Shaw, Alice T; Friboulet, Luc; Leshchiner, Ignaty; Gainor, Justin F; Bergqvist, Simon; Brooun, Alexei; Burke, Benjamin J; Deng, Ya-Li; Liu, Wei; Dardaei, Leila; Frias, Rosa L; Schultz, Kate R; Logan, Jennifer; James, Leonard P; Smeal, Tod; Timofeevski, Sergei; Katayama, Ryohei; Iafrate, A John; Le, Long; McTigue, Michele; Getz, Gad; Johnson, Ted W; Engelman, Jeffrey A.

N Engl J Med ; 374(1): 54-61, 2016 Jan 07.

Artículo en Inglés | MEDLINE | ID: mdl-26698910

14.

Lorlatinib in patients with ALK-positive non-small-cell lung cancer: results from a global phase 2 study.

Solomon, Benjamin J; Besse, Benjamin; Bauer, Todd M; Felip, Enriqueta; Soo, Ross A; Camidge, D Ross; Chiari, Rita; Bearz, Alessandra; Lin, Chia-Chi; Gadgeel, Shirish M; Riely, Gregory J; Tan, Eng Huat; Seto, Takashi; James, Leonard P; Clancy, Jill S; Abbattista, Antonello; Martini, Jean-François; Chen, Joseph; Peltz, Gerson; Thurm, Holger; Ou, Sai-Hong Ignatius; Shaw, Alice T.

Lancet Oncol ; 19(12): 1654-1667, 2018 12.

Artículo en Inglés | MEDLINE | ID: mdl-30413378

15.

Cumulative incidence rates for CNS and non-CNS progression in two phase II studies of alectinib in ALK-positive NSCLC.

Gadgeel, Shirish; Shaw, Alice T; Barlesi, Fabrice; Crinò, Lucio; Yang, James Chih-Hsin; Dingemans, Anne-Marie C; Kim, Dong-Wan; de Marinis, Filippo; Schulz, Mathias; Liu, Shiyao; Gupta, Ravindra; Kotb, Ahmed; Ou, Sai-Hong Ignatius.

Br J Cancer ; 118(1): 38-42, 2018 01.

Artículo en Inglés | MEDLINE | ID: mdl-29149104

16.

Improved tumor vascularization after anti-VEGF therapy with carboplatin and nab-paclitaxel associates with survival in lung cancer.

Heist, Rebecca S; Duda, Dan G; Sahani, Dushyant V; Ancukiewicz, Marek; Fidias, Panos; Sequist, Lecia V; Temel, Jennifer S; Shaw, Alice T; Pennell, Nathan A; Neal, Joel W; Gandhi, Leena; Lynch, Thomas J; Engelman, Jeffrey A; Jain, Rakesh K.

Proc Natl Acad Sci U S A ; 112(5): 1547-52, 2015 Feb 03.

Artículo en Inglés | MEDLINE | ID: mdl-25605928

17.

Ceritinib versus chemotherapy in patients with ALK-rearranged non-small-cell lung cancer previously given chemotherapy and crizotinib (ASCEND-5): a randomised, controlled, open-label, phase 3 trial.

Shaw, Alice T; Kim, Tae Min; Crinò, Lucio; Gridelli, Cesare; Kiura, Katsuyuki; Liu, Geoffrey; Novello, Silvia; Bearz, Alessandra; Gautschi, Oliver; Mok, Tony; Nishio, Makoto; Scagliotti, Giorgio; Spigel, David R; Deudon, Stéphanie; Zheng, Cheng; Pantano, Serafino; Urban, Patrick; Massacesi, Cristian; Viraswami-Appanna, Kalyanee; Felip, Enriqueta.

Lancet Oncol ; 18(7): 874-886, 2017 07.

Artículo en Inglés | MEDLINE | ID: mdl-28602779

18.

Lorlatinib in non-small-cell lung cancer with ALK or ROS1 rearrangement: an international, multicentre, open-label, single-arm first-in-man phase 1 trial.

Shaw, Alice T; Felip, Enriqueta; Bauer, Todd M; Besse, Benjamin; Navarro, Alejandro; Postel-Vinay, Sophie; Gainor, Justin F; Johnson, Melissa; Dietrich, Jorg; James, Leonard P; Clancy, Jill S; Chen, Joseph; Martini, Jean-François; Abbattista, Antonello; Solomon, Benjamin J.

Lancet Oncol ; 18(12): 1590-1599, 2017 12.

Artículo en Inglés | MEDLINE | ID: mdl-29074098

19.

Ceritinib in ALK-rearranged non-small-cell lung cancer.

Shaw, Alice T; Kim, Dong-Wan; Mehra, Ranee; Tan, Daniel S W; Felip, Enriqueta; Chow, Laura Q M; Camidge, D Ross; Vansteenkiste, Johan; Sharma, Sunil; De Pas, Tommaso; Riely, Gregory J; Solomon, Benjamin J; Wolf, Juergen; Thomas, Michael; Schuler, Martin; Liu, Geoffrey; Santoro, Armando; Lau, Yvonne Y; Goldwasser, Meredith; Boral, Anthony L; Engelman, Jeffrey A.

N Engl J Med ; 370(13): 1189-97, 2014 Mar 27.

Artículo en Inglés | MEDLINE | ID: mdl-24670165

20.

Crizotinib in ROS1-rearranged non-small-cell lung cancer.

Shaw, Alice T; Ou, Sai-Hong I; Bang, Yung-Jue; Camidge, D Ross; Solomon, Benjamin J; Salgia, Ravi; Riely, Gregory J; Varella-Garcia, Marileila; Shapiro, Geoffrey I; Costa, Daniel B; Doebele, Robert C; Le, Long Phi; Zheng, Zongli; Tan, Weiwei; Stephenson, Patricia; Shreeve, S Martin; Tye, Lesley M; Christensen, James G; Wilner, Keith D; Clark, Jeffrey W; Iafrate, A John.

N Engl J Med ; 371(21): 1963-71, 2014 Nov 20.

Artículo en Inglés | MEDLINE | ID: mdl-25264305

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