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1.
Evidence that the multiflorine-derived substituted quinazolidine 55P0251 augments insulin secretion and lowers blood glucose via antagonism at α2 -adrenoceptors in mice.
Diabetes Obes Metab
; 22(3): 290-302, 2020 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-31608542
2.
Preclinical characterization of 55P0251, a novel compound that amplifies glucose-stimulated insulin secretion and counteracts hyperglycaemia in rodents.
Diabetes Obes Metab
; 19(8): 1088-1096, 2017 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-28211608
3.
Lipophilicity as a determinant of thiazolidinedione action in vitro: findings from BLX-1002, a novel compound without affinity to PPARs.
Am J Physiol Cell Physiol
; 300(6): C1386-92, 2011 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-21346152
4.
The effects of amino acids on glucose metabolism of isolated rat skeletal muscle are independent of insulin and the mTOR/S6K pathway.
Am J Physiol Endocrinol Metab
; 297(3): E785-92, 2009 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-19622787
5.
Age-dependent development of metabolic derangement and effects of intervention with pioglitazone in Zucker diabetic fatty rats.
J Pharmacol Exp Ther
; 326(1): 323-9, 2008 Jul.
Artículo
en Inglés
| MEDLINE | ID: mdl-18445783
6.
55P0110, a Novel Synthetic Compound Developed from a Plant Derived Backbone Structure, Shows Promising Anti-Hyperglycaemic Activity in Mice.
PLoS One
; 10(5): e0126847, 2015.
Artículo
en Inglés
| MEDLINE | ID: mdl-25973898
7.
Dissection of mechanisms that account for imidazoline-induced lowering of blood glucose in mice.
Eur J Pharmacol
; 741: 178-85, 2014 Oct 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25149664
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