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1.
Characterization of Pharmacokinetics, Biotransformation and Elimination of Pomotrelvir Orally Administered in Healthy Male Adults Using Two [14C]-Labeled Microtracers with Separate Labeling Positions.
Drug Metab Dispos
; 51(12): 1607-1614, 2023 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-37684056
2.
A Novel Immune Modulator for Patients With Necrotizing Soft Tissue Infections (NSTI): Results of a Multicenter, Phase 3 Randomized Controlled Trial of Reltecimod (AB 103).
Ann Surg
; 272(3): 469-478, 2020 09 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-32657946
3.
Effects of enzyme inducers efavirenz and tipranavir/ritonavir on the pharmacokinetics of the HIV integrase inhibitor dolutegravir.
Eur J Clin Pharmacol
; 70(10): 1173-9, 2014 Oct.
Artículo
en Inglés
| MEDLINE | ID: mdl-25146692
4.
SARS-CoV-2 viral dynamics in a placebo-controlled phase 2 study of patients infected with the SARS-CoV-2 Omicron variant and treated with pomotrelvir.
Microbiol Spectr
; 12(2): e0298023, 2024 Feb 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-38197702
5.
A comprehensive evaluation in clinic and physiologically-based pharmacokinetic modeling and simulation to confirm lack of cytochrome P450-mediated drug-drug interaction potential for pomotrelvir.
CPT Pharmacometrics Syst Pharmacol
; 12(10): 1553-1564, 2023 10.
Artículo
en Inglés
| MEDLINE | ID: mdl-37614073
6.
Resolution of organ dysfunction as a predictor of long-term survival in necrotizing soft tissue infections: Analysis of the AB103 Clinical Composite Endpoint Study in Necrotizing Soft Tissue Infections trial and a retrospective claims database-linked chart study.
J Trauma Acute Care Surg
; 91(2): 384-392, 2021 08 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33797490
7.
Estimating the Impact of Necrotizing Soft Tissue Infections in the United States: Incidence and Re-Admissions.
Surg Infect (Larchmt)
; 22(5): 509-515, 2021 Jun.
Artículo
en Inglés
| MEDLINE | ID: mdl-32833599
8.
Epidemiology of respiratory syncytial virus in various regions within North Carolina during multiple seasons.
N C Med J
; 69(6): 447-52, 2008.
Artículo
en Inglés
| MEDLINE | ID: mdl-19256181
9.
Effects of omeprazole and ritonavir on absorption and elimination of the hepatitis C virus NS5A inhibitor GSK2336805 in healthy adults.
Clin Pharmacol Drug Dev
; 3(5): 338-45, 2014 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-27129005
10.
GSK1265744 pharmacokinetics in plasma and tissue after single-dose long-acting injectable administration in healthy subjects.
J Acquir Immune Defic Syndr
; 67(5): 481-6, 2014 Dec 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-25140909
11.
A randomized, double blind, dose escalation, first time in human study to assess the safety, tolerability, pharmacokinetics, and antiviral activity of single doses of GSK2485852 in chronically infected hepatitis C subjects.
Clin Pharmacol Drug Dev
; 3(6): 439-48, 2014 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-27129119
12.
No association found between the detection of either xenotropic murine leukemia virus-related virus or polytropic murine leukemia virus and chronic fatigue syndrome in a blinded, multi-site, prospective study by the establishment and use of the SolveCFS BioBank.
BMC Res Notes
; 7: 461, 2014 Aug 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-25092471
13.
Microfluidic platform versus conventional real-time polymerase chain reaction for the detection of Mycoplasma pneumoniae in respiratory specimens.
Diagn Microbiol Infect Dis
; 67(1): 22-9, 2010 May.
Artículo
en Inglés
| MEDLINE | ID: mdl-20227222
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