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1.
Alzheimer risk-increasing TREM2 variant causes aberrant cortical synapse density and promotes network hyperexcitability in mouse models.
Neurobiol Dis
; 186: 106263, 2023 10 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-37591465
2.
Klotho controls the brain-immune system interface in the choroid plexus.
Proc Natl Acad Sci U S A
; 115(48): E11388-E11396, 2018 11 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-30413620
3.
Neuronal levels and sequence of tau modulate the power of brain rhythms.
Neurobiol Dis
; 117: 181-188, 2018 09.
Artículo
en Inglés
| MEDLINE | ID: mdl-29859869
4.
Istradefylline reduces memory deficits in aging mice with amyloid pathology.
Neurobiol Dis
; 110: 29-36, 2018 02.
Artículo
en Inglés
| MEDLINE | ID: mdl-29100987
5.
Expression of A152T human tau causes age-dependent neuronal dysfunction and loss in transgenic mice.
EMBO Rep
; 17(4): 530-51, 2016 04.
Artículo
en Inglés
| MEDLINE | ID: mdl-26931567
6.
Reversing EphB2 depletion rescues cognitive functions in Alzheimer model.
Nature
; 469(7328): 47-52, 2011 Jan 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-21113149
7.
Life extension factor klotho prevents mortality and enhances cognition in hAPP transgenic mice.
J Neurosci
; 35(6): 2358-71, 2015 Feb 11.
Artículo
en Inglés
| MEDLINE | ID: mdl-25673831
8.
Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model.
Proc Natl Acad Sci U S A
; 109(42): E2895-903, 2012 Oct 16.
Artículo
en Inglés
| MEDLINE | ID: mdl-22869752
9.
Ablation of cellular prion protein does not ameliorate abnormal neural network activity or cognitive dysfunction in the J20 line of human amyloid precursor protein transgenic mice.
J Neurosci
; 31(29): 10427-31, 2011 Jul 20.
Artículo
en Inglés
| MEDLINE | ID: mdl-21775587
10.
Amyloid-ß/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease.
J Neurosci
; 31(2): 700-11, 2011 Jan 12.
Artículo
en Inglés
| MEDLINE | ID: mdl-21228179
11.
TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model.
Sci Transl Med
; 14(642): eabm5527, 2022 04 27.
Artículo
en Inglés
| MEDLINE | ID: mdl-35476595
12.
Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease.
Neuron
; 55(5): 697-711, 2007 Sep 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-17785178
13.
Many neuronal and behavioral impairments in transgenic mouse models of Alzheimer's disease are independent of caspase cleavage of the amyloid precursor protein.
J Neurosci
; 30(1): 372-81, 2010 Jan 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-20053918
14.
Cellular source of apolipoprotein E4 determines neuronal susceptibility to excitotoxic injury in transgenic mice.
Am J Pathol
; 177(2): 563-9, 2010 Aug.
Artículo
en Inglés
| MEDLINE | ID: mdl-20595630
15.
Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchrony.
Cell Rep
; 37(3): 109855, 2021 10 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-34686344
16.
Interdependence of neural network dysfunction and microglial alterations in Alzheimer's disease-related models.
iScience
; 24(11): 103245, 2021 Nov 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-34755090
17.
Phenotypic Differences between the Alzheimer's Disease-Related hAPP-J20 Model and Heterozygous Zbtb20 Knock-Out Mice.
eNeuro
; 8(3)2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33833046
18.
Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice.
J Neurosci
; 29(7): 1977-86, 2009 Feb 18.
Artículo
en Inglés
| MEDLINE | ID: mdl-19228952
19.
Tau Reduction Prevents Key Features of Autism in Mouse Models.
Neuron
; 106(3): 421-437.e11, 2020 05 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-32126198
20.
Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1.
Mol Neurodegener
; 15(1): 53, 2020 09 14.
Artículo
en Inglés
| MEDLINE | ID: mdl-32921309