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1.

CRB1-associated retinal degeneration is dependent on bacterial translocation from the gut.

Peng, Shanzhen; Li, Jing Jing; Song, Wanying; Li, Ye; Zeng, Lei; Liang, Qiaoxing; Wen, Xiaofeng; Shang, Haitao; Liu, Keli; Peng, Peiyao; Xue, Wei; Zou, Bin; Yang, Liu; Liang, Juanran; Zhang, Zhihui; Guo, Shixin; Chen, Tingting; Li, Wenxuan; Jin, Ming; Xing, Xiang-Bin; Wan, Pengxia; Liu, Chunqiao; Lin, Haotian; Wei, Hong; Lee, Richard W J; Zhang, Feng; Wei, Lai.

Cell ; 187(6): 1387-1401.e13, 2024 Mar 14.

Artículo en Inglés | MEDLINE | ID: mdl-38412859

2.

A transcription factor atlas of directed differentiation.

Joung, Julia; Ma, Sai; Tay, Tristan; Geiger-Schuller, Kathryn R; Kirchgatterer, Paul C; Verdine, Vanessa K; Guo, Baolin; Arias-Garcia, Mario A; Allen, William E; Singh, Ankita; Kuksenko, Olena; Abudayyeh, Omar O; Gootenberg, Jonathan S; Fu, Zhanyan; Macrae, Rhiannon K; Buenrostro, Jason D; Regev, Aviv; Zhang, Feng.

Cell ; 186(1): 209-229.e26, 2023 01 05.

Artículo en Inglés | MEDLINE | ID: mdl-36608654

3.

Dual modes of CRISPR-associated transposon homing.

Saito, Makoto; Ladha, Alim; Strecker, Jonathan; Faure, Guilhem; Neumann, Edwin; Altae-Tran, Han; Macrae, Rhiannon K; Zhang, Feng.

Cell ; 184(9): 2441-2453.e18, 2021 04 29.

Artículo en Inglés | MEDLINE | ID: mdl-33770501

4.

A cellular and spatial map of the choroid plexus across brain ventricles and ages.

Dani, Neil; Herbst, Rebecca H; McCabe, Cristin; Green, Gilad S; Kaiser, Karol; Head, Joshua P; Cui, Jin; Shipley, Frederick B; Jang, Ahram; Dionne, Danielle; Nguyen, Lan; Rodman, Christopher; Riesenfeld, Samantha J; Prochazka, Jan; Prochazkova, Michaela; Sedlacek, Radislav; Zhang, Feng; Bryja, Vitezslav; Rozenblatt-Rosen, Orit; Habib, Naomi; Regev, Aviv; Lehtinen, Maria K.

Cell ; 184(11): 3056-3074.e21, 2021 05 27.

Artículo en Inglés | MEDLINE | ID: mdl-33932339

5.

Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro.

Dolan, Michael-John; Therrien, Martine; Jereb, Sasa; Kamath, Tushar; Gazestani, Vahid; Atkeson, Trevor; Marsh, Samuel E; Goeva, Aleksandrina; Lojek, Neal M; Murphy, Sarah; White, Cassandra M; Joung, Julia; Liu, Bingxu; Limone, Francesco; Eggan, Kevin; Hacohen, Nir; Bernstein, Bradley E; Glass, Christopher K; Leinonen, Ville; Blurton-Jones, Mathew; Zhang, Feng; Epstein, Charles B; Macosko, Evan Z; Stevens, Beth.

Nat Immunol ; 24(8): 1382-1390, 2023 08.

Artículo en Inglés | MEDLINE | ID: mdl-37500887

6.

CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors.

Wang, Dan; Zhang, Feng; Gao, Guangping.

Cell ; 181(1): 136-150, 2020 04 02.

Artículo en Inglés | MEDLINE | ID: mdl-32243786

7.

DNA Microscopy: Optics-free Spatio-genetic Imaging by a Stand-Alone Chemical Reaction.

Weinstein, Joshua A; Regev, Aviv; Zhang, Feng.

Cell ; 178(1): 229-241.e16, 2019 06 27.

Artículo en Inglés | MEDLINE | ID: mdl-31230717

8.

Optical Pooled Screens in Human Cells.

Feldman, David; Singh, Avtar; Schmid-Burgk, Jonathan L; Carlson, Rebecca J; Mezger, Anja; Garrity, Anthony J; Zhang, Feng; Blainey, Paul C.

Cell ; 179(3): 787-799.e17, 2019 10 17.

Artículo en Inglés | MEDLINE | ID: mdl-31626775

9.

A transcription factor atlas of directed differentiation.

Joung, Julia; Ma, Sai; Tay, Tristan; Geiger-Schuller, Kathryn R; Kirchgatterer, Paul C; Verdine, Vanessa K; Guo, Baolin; Arias-Garcia, Mario A; Allen, William E; Singh, Ankita; Kuksenko, Olena; Abudayyeh, Omar O; Gootenberg, Jonathan S; Fu, Zhanyan; Macrae, Rhiannon K; Buenrostro, Jason D; Regev, Aviv; Zhang, Feng.

Cell ; 2024 May 01.

Artículo en Inglés | MEDLINE | ID: mdl-38697106

10.

SnapShot: Class 1 CRISPR-Cas Systems.

Makarova, Kira S; Zhang, Feng; Koonin, Eugene V.

Cell ; 168(5): 946-946.e1, 2017 02 23.

Artículo en Inglés | MEDLINE | ID: mdl-28235204

11.

SnapShot: Class 2 CRISPR-Cas Systems.

Makarova, Kira S; Zhang, Feng; Koonin, Eugene V.

Cell ; 168(1-2): 328-328.e1, 2017 Jan 12.

Artículo en Inglés | MEDLINE | ID: mdl-28086097

12.

An Organismal CNV Mutator Phenotype Restricted to Early Human Development.

Liu, Pengfei; Yuan, Bo; Carvalho, Claudia M B; Wuster, Arthur; Walter, Klaudia; Zhang, Ling; Gambin, Tomasz; Chong, Zechen; Campbell, Ian M; Coban Akdemir, Zeynep; Gelowani, Violet; Writzl, Karin; Bacino, Carlos A; Lindsay, Sarah J; Withers, Marjorie; Gonzaga-Jauregui, Claudia; Wiszniewska, Joanna; Scull, Jennifer; Stankiewicz, Pawel; Jhangiani, Shalini N; Muzny, Donna M; Zhang, Feng; Chen, Ken; Gibbs, Richard A; Rautenstrauss, Bernd; Cheung, Sau Wai; Smith, Janice; Breman, Amy; Shaw, Chad A; Patel, Ankita; Hurles, Matthew E; Lupski, James R.

Cell ; 168(5): 830-842.e7, 2017 02 23.

Artículo en Inglés | MEDLINE | ID: mdl-28235197

13.

Structure and Engineering of Francisella novicida Cas9.

Hirano, Hisato; Gootenberg, Jonathan S; Horii, Takuro; Abudayyeh, Omar O; Kimura, Mika; Hsu, Patrick D; Nakane, Takanori; Ishitani, Ryuichiro; Hatada, Izuho; Zhang, Feng; Nishimasu, Hiroshi; Nureki, Osamu.

Cell ; 164(5): 950-61, 2016 Feb 25.

Artículo en Inglés | MEDLINE | ID: mdl-26875867

14.

Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA.

Yamano, Takashi; Nishimasu, Hiroshi; Zetsche, Bernd; Hirano, Hisato; Slaymaker, Ian M; Li, Yinqing; Fedorova, Iana; Nakane, Takanori; Makarova, Kira S; Koonin, Eugene V; Ishitani, Ryuichiro; Zhang, Feng; Nureki, Osamu.

Cell ; 165(4): 949-62, 2016 May 05.

Artículo en Inglés | MEDLINE | ID: mdl-27114038

15.

Modularity and diversity of target selectors in Tn7 transposons.

Faure, Guilhem; Saito, Makoto; Benler, Sean; Peng, Iris; Wolf, Yuri I; Strecker, Jonathan; Altae-Tran, Han; Neumann, Edwin; Li, David; Makarova, Kira S; Macrae, Rhiannon K; Koonin, Eugene V; Zhang, Feng.

Mol Cell ; 83(12): 2122-2136.e10, 2023 Jun 15.

Artículo en Inglés | MEDLINE | ID: mdl-37267947

16.

Crystal Structure of Staphylococcus aureus Cas9.

Nishimasu, Hiroshi; Cong, Le; Yan, Winston X; Ran, F Ann; Zetsche, Bernd; Li, Yinqing; Kurabayashi, Arisa; Ishitani, Ryuichiro; Zhang, Feng; Nureki, Osamu.

Cell ; 162(5): 1113-26, 2015 Aug 27.

Artículo en Inglés | MEDLINE | ID: mdl-26317473

17.

Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis.

Chen, Sidi; Sanjana, Neville E; Zheng, Kaijie; Shalem, Ophir; Lee, Kyungheon; Shi, Xi; Scott, David A; Song, Jun; Pan, Jen Q; Weissleder, Ralph; Lee, Hakho; Zhang, Feng; Sharp, Phillip A.

Cell ; 160(6): 1246-60, 2015 Mar 12.

Artículo en Inglés | MEDLINE | ID: mdl-25748654

18.

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks.

Parnas, Oren; Jovanovic, Marko; Eisenhaure, Thomas M; Herbst, Rebecca H; Dixit, Atray; Ye, Chun Jimmie; Przybylski, Dariusz; Platt, Randall J; Tirosh, Itay; Sanjana, Neville E; Shalem, Ophir; Satija, Rahul; Raychowdhury, Raktima; Mertins, Philipp; Carr, Steven A; Zhang, Feng; Hacohen, Nir; Regev, Aviv.

Cell ; 162(3): 675-86, 2015 Jul 30.

Artículo en Inglés | MEDLINE | ID: mdl-26189680

19.

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.

Zetsche, Bernd; Gootenberg, Jonathan S; Abudayyeh, Omar O; Slaymaker, Ian M; Makarova, Kira S; Essletzbichler, Patrick; Volz, Sara E; Joung, Julia; van der Oost, John; Regev, Aviv; Koonin, Eugene V; Zhang, Feng.

Cell ; 163(3): 759-71, 2015 Oct 22.

Artículo en Inglés | MEDLINE | ID: mdl-26422227

20.

Structure and engineering of the minimal type VI CRISPR-Cas13bt3.

Nakagawa, Ryoya; Kannan, Soumya; Altae-Tran, Han; Takeda, Satoru N; Tomita, Atsuhiro; Hirano, Hisato; Kusakizako, Tsukasa; Nishizawa, Tomohiro; Yamashita, Keitaro; Zhang, Feng; Nishimasu, Hiroshi; Nureki, Osamu.

Mol Cell ; 82(17): 3178-3192.e5, 2022 09 01.

Artículo en Inglés | MEDLINE | ID: mdl-36027912

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CRB1-associated retinal degeneration is dependent on bacterial translocation from the gut.

A transcription factor atlas of directed differentiation.

Dual modes of CRISPR-associated transposon homing.

A cellular and spatial map of the choroid plexus across brain ventricles and ages.

Exposure of iPSC-derived human microglia to brain substrates enables the generation and manipulation of diverse transcriptional states in vitro.

CRISPR-Based Therapeutic Genome Editing: Strategies and In Vivo Delivery by AAV Vectors.

DNA Microscopy: Optics-free Spatio-genetic Imaging by a Stand-Alone Chemical Reaction.

Optical Pooled Screens in Human Cells.

A transcription factor atlas of directed differentiation.

SnapShot: Class 1 CRISPR-Cas Systems.

SnapShot: Class 2 CRISPR-Cas Systems.

An Organismal CNV Mutator Phenotype Restricted to Early Human Development.

Structure and Engineering of Francisella novicida Cas9.

Crystal Structure of Cpf1 in Complex with Guide RNA and Target DNA.

Modularity and diversity of target selectors in Tn7 transposons.

Crystal Structure of Staphylococcus aureus Cas9.

Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis.

A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks.

Cpf1 is a single RNA-guided endonuclease of a class 2 CRISPR-Cas system.

Structure and engineering of the minimal type VI CRISPR-Cas13bt3.