Detalhe da pesquisa
1.
Pharmacokinetics and safety of LEAD-452, an EGFR-specific 4-1BB-agonistic trimerbody in non-human primates.
Toxicol Appl Pharmacol
; 487: 116961, 2024 May 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38740095
2.
T Cell-Redirecting Strategies to 'STAb' Tumors: Beyond CARs and Bispecific Antibodies.
Trends Immunol
; 40(3): 243-257, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30827461
3.
Immuno-PET Imaging and Pharmacokinetics of an Anti-CEA scFv-based Trimerbody and Its Monomeric Counterpart in Human Gastric Carcinoma-Bearing Mice.
Mol Pharm
; 16(3): 1025-1035, 2019 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30726099
4.
Bispecific light T-cell engagers for gene-based immunotherapy of epidermal growth factor receptor (EGFR)-positive malignancies.
Cancer Immunol Immunother
; 67(8): 1251-1260, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29869168
5.
Role of nucleotide-binding oligomerization domain 1 (NOD1) in pericyte-mediated vascular inflammation.
J Cell Mol Med
; 20(5): 980-6, 2016 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-26915562
6.
Efficacy and toxicity management of CAR-T-cell immunotherapy: a matter of responsiveness control or tumour-specificity?
Biochem Soc Trans
; 44(2): 406-11, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27068947
7.
Proteasome activator complex PA28 identified as an accessible target in prostate cancer by in vivo selection of human antibodies.
Proc Natl Acad Sci U S A
; 110(34): 13791-6, 2013 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-23918357
8.
Lipopolysaccharide activates Toll-like receptor 4 (TLR4)-mediated NF-κB signaling pathway and proinflammatory response in human pericytes.
J Biol Chem
; 289(4): 2457-68, 2014 Jan 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24307174
9.
Perforin gene variant A91V in young patients with severe COVID-19.
Haematologica
; 105(12): 2844-2846, 2020 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33256384
10.
Efficient production of single-chain fragment variable-based N-terminal trimerbodies in Pichia pastoris.
Microb Cell Fact
; 13: 116, 2014 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-25112455
11.
The efficacy versus toxicity profile of combination virotherapy and TLR immunotherapy highlights the danger of administering TLR agonists to oncolytic virus-treated mice.
Mol Ther
; 21(2): 348-57, 2013 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-23011032
12.
Combination of T cell-redirecting strategies with a bispecific antibody blocking TGF-ß and PD-L1 enhances antitumor responses.
Oncoimmunology
; 13(1): 2338558, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38623463
13.
Characterization of a Trispecific PD-L1 Blocking Antibody That Exhibits EGFR-Conditional 4-1BB Agonist Activity.
Antibodies (Basel)
; 13(2)2024 Apr 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38804302
14.
Engineered T cells secreting anti-BCMA T cell engagers control multiple myeloma and promote immune memory in vivo.
Sci Transl Med
; 16(734): eadg7962, 2024 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38354229
15.
Bi- and trispecific immune cell engagers for immunotherapy of hematological malignancies.
J Hematol Oncol
; 16(1): 83, 2023 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-37501154
16.
When three is not a crowd: trispecific antibodies for enhanced cancer immunotherapy.
Theranostics
; 13(3): 1028-1041, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36793863
17.
A PD-L1/EGFR bispecific antibody combines immune checkpoint blockade and direct anti-cancer action for an enhanced anti-tumor response.
Oncoimmunology
; 12(1): 2205336, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37114242
18.
10th antibody industrial symposium: new developments in antibody and adoptive cell therapies.
MAbs
; 15(1): 2211692, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37184206
19.
Dendritic Cell-Mediated Cross-Priming by a Bispecific Neutralizing Antibody Boosts Cytotoxic T Cell Responses and Protects Mice against SARS-CoV-2.
Adv Sci (Weinh)
; 10(34): e2304818, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37863812
20.
The multicompartmental p32/gClqR as a new target for antibody-based tumor targeting strategies.
J Biol Chem
; 286(7): 5197-203, 2011 Feb 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-21156793