Detalhe da pesquisa
1.
A diversity-oriented synthesis approach to macrocycles via oxidative ring expansion.
Nat Chem Biol
; 8(4): 358-65, 2012 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-22406518
2.
Fragment-based domain shuffling approach for the synthesis of pyran-based macrocycles.
Proc Natl Acad Sci U S A
; 108(17): 6751-6, 2011 Apr 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21383141
3.
Synthesis of stereochemically and skeletally diverse fused ring systems from functionalized C-glycosides.
J Org Chem
; 78(11): 5160-71, 2013 Jun 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-23692141
4.
An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse libraries.
J Comput Aided Mol Des
; 27(5): 455-68, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23585218
5.
Synthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries.
J Org Chem
; 77(17): 7187-211, 2012 Sep 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-22853001
6.
An aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.
J Am Chem Soc
; 132(47): 16962-76, 2010 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21067169
7.
Application of a catalytic asymmetric Povarov reaction using chiral ureas to the synthesis of a tetrahydroquinoline library.
ACS Comb Sci
; 14(11): 621-30, 2012 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-23088641
8.
Build/couple/pair strategy for the synthesis of stereochemically diverse macrolactams via head-to-tail cyclization.
ACS Comb Sci
; 14(2): 89-96, 2012 Feb 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-22252910
9.
Application of a sparse matrix design strategy to the synthesis of dos libraries.
ACS Comb Sci
; 13(4): 357-64, 2011 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21526822
10.
Synthesis of a stereochemically diverse library of medium-sized lactams and sultams via S(N)Ar cycloetherification.
ACS Comb Sci
; 13(4): 365-74, 2011 Jul 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-21526820
11.
Cheminformatics approaches to analyze diversity in compound screening libraries.
Curr Opin Chem Biol
; 14(3): 325-30, 2010 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-20457001
12.
Structural unit analysis identifies lead series and facilitates scaffold hopping in combinatorial chemistry.
J Chem Inf Model
; 46(3): 1188-93, 2006.
Artigo
em Inglês
| MEDLINE | ID: mdl-16711738