Detalhe da pesquisa
1.
Probing the Cytotoxic Signaling Induced by Eupenifeldin in Ovarian Cancer Models.
J Nat Prod
; 86(9): 2102-2110, 2023 09 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37643353
2.
Discovery of Anticancer Agents of Diverse Natural Origin.
J Nat Prod
; 85(3): 702-719, 2022 03 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35213158
3.
Beclin 1-ATG14L Protein-Protein Interaction Inhibitor Selectively Inhibits Autophagy through Disruption of VPS34 Complex I.
J Am Chem Soc
; 142(18): 8174-8182, 2020 05 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32320221
4.
Multiple Chemical Features Impact Biological Performance Diversity of a Highly Active Natural Product-Inspired Library.
Chembiochem
; 21(21): 3137-3145, 2020 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32558167
5.
Next generation diversity-oriented synthesis: a paradigm shift from chemical diversity to biological diversity.
Org Biomol Chem
; 17(7): 1608-1623, 2019 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30328455
6.
Microwave-Assisted, Asymmetric Synthesis of 3-Amino-2,3-Dihydrobenzofuran Flavonoid Derivatives from Chalcones.
Chemistry
; 24(18): 4509-4514, 2018 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29446184
7.
Small-molecule enhancers of autophagy modulate cellular disease phenotypes suggested by human genetics.
Proc Natl Acad Sci U S A
; 112(31): E4281-7, 2015 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26195741
8.
Lipids lead the way.
Nat Chem Biol
; 15(7): 653-654, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-31222191
10.
Discovery of a Small-Molecule Probe for V-ATPase Function.
J Am Chem Soc
; 137(16): 5563-8, 2015 Apr 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-25860544
11.
Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection.
Gastroenterology
; 145(6): 1347-57, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23973919
12.
Spiroaminal Model Systems of the Marineosins with Final Step Pyrrole Incorporation.
Tetrahedron Lett
; 54(18): 2231-2234, 2013 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23606772
13.
Towards the Total Synthesis of Marineosin A: Construction of the Macrocyclic Pyrrole and an Advanced, Functionalized Spiroaminal Model.
European J Org Chem
; 2013(20)2013 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24415906
14.
Discovery of a Small-Molecule Modulator of the Autophagy-Lysosome Pathway That Targets Lamin A/C and LAMP1, Induces Autophagic Flux, and Affects Lysosome Positioning in Neurons.
ACS Chem Neurosci
; 14(24): 4363-4382, 2023 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-38069806
15.
PHY34 inhibits autophagy through V-ATPase V0A2 subunit inhibition and CAS/CSE1L nuclear cargo trafficking in high grade serous ovarian cancer.
Cell Death Dis
; 13(1): 45, 2022 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-35013112
16.
Development of a High-Throughput, Compound-Multiplexed Fluorescence Polarization Assay to Identify ATG5-ATG16L1 Protein-Protein Interaction Inhibitors.
SLAS Discov
; 26(7): 933-943, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33783243
17.
Autophagy and post-ischemic conditioning in retinal ischemia.
Autophagy
; 17(6): 1479-1499, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32452260
18.
Total synthesis and biological evaluation of tambjamine K and a library of unnatural analogs.
Bioorg Med Chem Lett
; 20(17): 5207-11, 2010 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20655217
19.
MAOS ls for the general synthesis and lead optimization of 3,6-disubstituted-[1,2,4]triazolo[4,3-b]pyridazines.
Tetrahedron Lett
; 50(2): 212-215, 2009 Jan 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-22090663
20.
Systematic Diversity-Oriented Synthesis of Reduced Flavones from γ-Pyrones to Probe Biological Performance Diversity.
ACS Chem Biol
; 14(7): 1536-1545, 2019 07 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-31184855