Detalhe da pesquisa
1.
Inhibition of MYC attenuates tumor cell self-renewal and promotes senescence in SMARCB1-deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo.
Int J Cancer
; 144(8): 1983-1995, 2019 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30230537
2.
Polo-like Kinase 1 as a potential therapeutic target in Diffuse Intrinsic Pontine Glioma.
BMC Cancer
; 16: 647, 2016 08 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27538997
3.
MicroRNA 218 acts as a tumor suppressor by targeting multiple cancer phenotype-associated genes in medulloblastoma.
J Biol Chem
; 288(3): 1918-28, 2013 Jan 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-23212916
4.
Integrated genomic analysis identifies the mitotic checkpoint kinase WEE1 as a novel therapeutic target in medulloblastoma.
Mol Cancer
; 13: 72, 2014 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-24661910
5.
Inhibition of cyclin-dependent kinase 6 suppresses cell proliferation and enhances radiation sensitivity in medulloblastoma cells.
J Neurooncol
; 111(2): 113-21, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23138228
6.
The PARP inhibitor Rucaparib synergizes with radiation to attenuate atypical teratoid rhabdoid tumor growth.
Neurooncol Adv
; 5(1): vdad010, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36915612
7.
Targeting the enhancer of zeste homologue 2 in medulloblastoma.
Int J Cancer
; 131(8): 1800-9, 2012 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22287205
8.
Polo-like kinase 1 (PLK1) inhibition suppresses cell growth and enhances radiation sensitivity in medulloblastoma cells.
BMC Cancer
; 12: 80, 2012 Mar 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-22390279
9.
Targeting Aurora Kinase A enhances radiation sensitivity of atypical teratoid rhabdoid tumor cells.
J Neurooncol
; 107(3): 517-26, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22246202
10.
Targeting the TP53/MDM2 axis enhances radiation sensitivity in atypical teratoid rhabdoid tumors.
Int J Oncol
; 60(3)2022 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35179215
11.
A novel PLK1 inhibitor onvansertib effectively sensitizes MYC-driven medulloblastoma to radiotherapy.
Neuro Oncol
; 24(3): 414-426, 2022 03 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34477871
12.
Loss of CAK phosphorylation of RAR{alpha} mediates transcriptional control of retinoid-induced cancer cell differentiation.
FASEB J
; 24(3): 833-43, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-19917671
13.
Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG.
Cell Rep
; 33(3): 108286, 2020 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33086074
14.
Targeting Polo-like kinase 1 in SMARCB1 deleted atypical teratoid rhabdoid tumor.
Oncotarget
; 8(57): 97290-97303, 2017 Nov 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-29228610
15.
MPS1 kinase as a potential therapeutic target in medulloblastoma.
Oncol Rep
; 36(5): 2633-2640, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27633003
16.
Checkpoint kinase 1 expression is an adverse prognostic marker and therapeutic target in MYC-driven medulloblastoma.
Oncotarget
; 7(33): 53881-53894, 2016 Aug 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27449089
17.
Effect of delta-sleep inducing peptide-containing preparation Deltaran on biomarkers of aging, life span and spontaneous tumor incidence in female SHR mice.
Mech Ageing Dev
; 124(6): 721-31, 2003 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-12782416
18.
Number of pregnancies and ovariectomy modify mammary carcinoma development in transgenic HER-2/neu female mice.
Cancer Lett
; 193(1): 49-55, 2003 Apr 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-12691823
19.
Dose-dependent effect of melatonin on life span and spontaneous tumor incidence in female SHR mice.
Exp Gerontol
; 38(4): 449-61, 2003 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-12670632
20.
Inhibition of BRD4 attenuates tumor cell self-renewal and suppresses stem cell signaling in MYC driven medulloblastoma.
Oncotarget
; 5(9): 2355-71, 2014 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24796395