Detalhe da pesquisa
1.
RFX6 haploinsufficiency predisposes to diabetes through impaired beta cell function.
Diabetologia
; 2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38743124
2.
Steroidogenic factor 1 (NR5A1) induces multiple transcriptional changes during differentiation of human gonadal-like cells.
Differentiation
; 128: 83-100, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36114074
3.
SUR1-mutant iPS cell-derived islets recapitulate the pathophysiology of congenital hyperinsulinism.
Diabetologia
; 64(3): 630-640, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33404684
4.
Concise Review: Human Pluripotent Stem Cells for the Modeling of Pancreatic ß-Cell Pathology.
Stem Cells
; 37(1): 33-41, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30270471
5.
Pancreatic ß-cell tRNA hypomethylation and fragmentation link TRMT10A deficiency with diabetes.
Nucleic Acids Res
; 46(19): 10302-10318, 2018 11 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30247717
6.
Genome editing of human pancreatic beta cell models: problems, possibilities and outlook.
Diabetologia
; 62(8): 1329-1336, 2019 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31161346
7.
Activin A and Wnt-dependent specification of human definitive endoderm cells.
Exp Cell Res
; 319(17): 2535-44, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23954819
8.
Efficient vascular and neural engraftment of stem cell-derived islets.
Diabetes
; 2024 Apr 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-38603470
9.
Primate-specific ZNF808 is essential for pancreatic development in humans.
Nat Genet
; 55(12): 2075-2081, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37973953
10.
Differentiating functional human islet-like aggregates from pluripotent stem cells.
STAR Protoc
; 3(4): 101711, 2022 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-36136756
11.
Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster.
Dev Cell
; 57(16): 1922-1936.e9, 2022 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-35998583
12.
CRISPR activation enables high-fidelity reprogramming into human pluripotent stem cells.
Stem Cell Reports
; 17(2): 413-426, 2022 02 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35063129
13.
The HASTER lncRNA promoter is a cis-acting transcriptional stabilizer of HNF1A.
Nat Cell Biol
; 24(10): 1528-1540, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36202974
14.
The type 1 diabetes gene TYK2 regulates ß-cell development and its responses to interferon-α.
Nat Commun
; 13(1): 6363, 2022 10 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36289205
15.
Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells.
Nat Biotechnol
; 40(7): 1042-1055, 2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35241836
16.
Human Pluripotent Stem Cells to Model Islet Defects in Diabetes.
Front Endocrinol (Lausanne)
; 12: 642152, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33828531
17.
Loss of MANF Causes Childhood-Onset Syndromic Diabetes Due to Increased Endoplasmic Reticulum Stress.
Diabetes
; 70(4): 1006-1018, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33500254
18.
Kaposi's Sarcoma-Associated Herpesvirus Reactivation by Targeting of a dCas9-Based Transcription Activator to the ORF50 Promoter.
Viruses
; 12(9)2020 08 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32867368
19.
Characterization of the human GnRH neuron developmental transcriptome using a GNRH1-TdTomato reporter line in human pluripotent stem cells.
Dis Model Mech
; 13(3)2020 03 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-31996360
20.
From research to rapid response: mass COVID-19 testing by volunteers at the Centre for Genomic Regulation.
F1000Res
; 9: 1336, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-34745570