Detalhe da pesquisa
1.
Ablation of the epithelial-specific splicing factor Esrp1 results in ureteric branching defects and reduced nephron number.
Dev Dyn
; 245(10): 991-1000, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27404344
2.
The splicing factor FUBP1 is required for the efficient splicing of oncogene MDM2 pre-mRNA.
J Biol Chem
; 289(25): 17350-64, 2014 Jun 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-24798327
3.
Hypoxia is a modifier of SMN2 splicing and disease severity in a severe SMA mouse model.
Hum Mol Genet
; 21(19): 4301-13, 2012 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22763238
4.
Genome-wide activities of RNA binding proteins that regulate cellular changes in the epithelial to mesenchymal transition (EMT).
Adv Exp Med Biol
; 825: 267-302, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25201109
5.
A humanized Smn gene containing the SMN2 nucleotide alteration in exon 7 mimics SMN2 splicing and the SMA disease phenotype.
Hum Mol Genet
; 19(21): 4239-52, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20705738
6.
Mouse models of SMA: tools for disease characterization and therapeutic development.
Hum Genet
; 131(8): 1277-93, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22543872
7.
Generation of a tamoxifen inducible SMN mouse for temporal SMN replacement.
Genesis
; 49(12): 927-34, 2011 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-21538807
8.
Conserved sequences in the final intron of MDM2 are essential for the regulation of alternative splicing of MDM2 in response to stress.
Exp Cell Res
; 315(19): 3419-32, 2009 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19631207
9.
ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development.
Dev Cell
; 43(3): 318-331.e5, 2017 11 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29107558
10.
Multiphasic and Dynamic Changes in Alternative Splicing during Induction of Pluripotency Are Coordinated by Numerous RNA-Binding Proteins.
Cell Rep
; 15(2): 247-55, 2016 Apr 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-27050523
11.
Determination of a Comprehensive Alternative Splicing Regulatory Network and Combinatorial Regulation by Key Factors during the Epithelial-to-Mesenchymal Transition.
Mol Cell Biol
; 36(11): 1704-19, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27044866
12.
The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian development.
Elife
; 42015 Sep 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26371508
13.
ESRP2 controls an adult splicing programme in hepatocytes to support postnatal liver maturation.
Nat Commun
; 6: 8768, 2015 Nov 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26531099
14.
Stress-induced alternative splice forms of MDM2 and MDMX modulate the p53-pathway in distinct ways.
PLoS One
; 9(8): e104444, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-25105592
15.
Splicing of the Survival Motor Neuron genes and implications for treatment of SMA
Front Biosci (Landmark Ed)
; 15(3): 1191-1204, 2010 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20515750