Detalhe da pesquisa
1.
Comparative analysis of CRISPR off-target discovery tools following ex vivo editing of CD34+ hematopoietic stem and progenitor cells.
Mol Ther
; 31(4): 1074-1087, 2023 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36793210
2.
Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells.
Blood
; 137(5): 624-636, 2021 02 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32902645
3.
Sequence-dependent inhibition of cGAS and TLR9 DNA sensing by 2'-O-methyl gapmer oligonucleotides.
Nucleic Acids Res
; 49(11): 6082-6099, 2021 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34057477
4.
Systematic in vitro profiling of off-target affinity, cleavage and efficiency for CRISPR enzymes.
Nucleic Acids Res
; 48(9): 5037-5053, 2020 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32315032
5.
Rational design of antisense oligonucleotides modulating the activity of TLR7/8 agonists.
Nucleic Acids Res
; 48(13): 7052-7065, 2020 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-32544249
6.
Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes.
Neurobiol Dis
; 147: 105148, 2021 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33184027
7.
Rational Design of Small Molecules to Enhance Genome Editing Efficiency by Selectively Targeting Distinct Functional States of CRISPR-Cas12a.
Bioconjug Chem
; 31(3): 542-546, 2020 03 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-32119776
8.
An Interferon Regulated MicroRNA Provides Broad Cell-Intrinsic Antiviral Immunity through Multihit Host-Directed Targeting of the Sterol Pathway.
PLoS Biol
; 14(3): e1002364, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26938778
9.
Simplified CRISPR tools for efficient genome editing and streamlined protocols for their delivery into mammalian cells and mouse zygotes.
Methods
; 121-122: 16-28, 2017 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28351759
10.
Rapid Detection of Urinary Tract Infections via Bacterial Nuclease Activity.
Mol Ther
; 25(6): 1353-1362, 2017 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28391960
11.
Cellular localization of long non-coding RNAs affects silencing by RNAi more than by antisense oligonucleotides.
Nucleic Acids Res
; 44(2): 863-77, 2016 Jan 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-26578588
12.
Cre-dependent DNA recombination activates a STING-dependent innate immune response.
Nucleic Acids Res
; 44(11): 5356-64, 2016 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-27166376
13.
SYVN1, NEDD8, and FBXO2 Proteins Regulate ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Ubiquitin-mediated Proteasomal Degradation.
J Biol Chem
; 291(49): 25489-25504, 2016 Dec 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27756846
14.
Sequence-dependent off-target inhibition of TLR7/8 sensing by synthetic microRNA inhibitors.
Nucleic Acids Res
; 43(2): 1177-88, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25539920
15.
Functional inhibition of chemokine receptor CCR2 by dicer-substrate-siRNA prevents pain development.
Mol Pain
; 122016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27306408
16.
miRNAs control insulin content in pancreatic ß-cells via downregulation of transcriptional repressors.
EMBO J
; 30(5): 835-45, 2011 Mar 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-21285947
17.
Pancreas-enriched miRNA refines endocrine cell differentiation.
Development
; 139(16): 3021-31, 2012 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-22764048
18.
Inosine-mediated modulation of RNA sensing by Toll-like receptor 7 (TLR7) and TLR8.
J Virol
; 88(2): 799-810, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24227841
19.
Knockdown of ß-catenin with dicer-substrate siRNAs reduces liver tumor burden in vivo.
Mol Ther
; 22(1): 92-101, 2014 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-24089139
20.
Quantitative assessment of ratiometric bimolecular beacons as a tool for imaging single engineered RNA transcripts and measuring gene expression in living cells.
Nucleic Acids Res
; 41(15): e152, 2013 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-23814183