Detalhe da pesquisa
1.
Development of novel ß2-adrenergic receptor agonists for the stimulation of glucose uptake - The importance of chirality and ring size of cyclic amines.
Bioorg Med Chem Lett
; 97: 129562, 2024 01 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37967654
2.
Hepatic Innervations and Nonalcoholic Fatty Liver Disease.
Semin Liver Dis
; 43(2): 149-162, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37156523
3.
Physiological and molecular mechanisms of cold-induced improvements in glucose homeostasis in humans beyond brown adipose tissue.
Int J Obes (Lond)
; 47(5): 338-347, 2023 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-36774412
4.
Brain integrity is altered by hepatic APOE ε4 in humanized-liver mice.
Mol Psychiatry
; 27(8): 3533-3543, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35418601
5.
Prolonged ß2-adrenergic agonist treatment improves glucose homeostasis in diet-induced obese UCP1-/- mice.
Am J Physiol Endocrinol Metab
; 320(3): E619-E628, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33522400
6.
Treatment with a ß-2-adrenoceptor agonist stimulates glucose uptake in skeletal muscle and improves glucose homeostasis, insulin resistance and hepatic steatosis in mice with diet-induced obesity.
Diabetologia
; 63(8): 1603-1615, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32472192
7.
BRL37344 stimulates GLUT4 translocation and glucose uptake in skeletal muscle via ß2-adrenoceptors without causing classical receptor desensitization.
Am J Physiol Regul Integr Comp Physiol
; 316(5): R666-R677, 2019 05 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30892909
8.
Adrenoceptors promote glucose uptake into adipocytes and muscle by an insulin-independent signaling pathway involving mechanistic target of rapamycin complex 2.
Pharmacol Res
; 116: 87-92, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28025104
9.
Protein kinase a-mediated cell proliferation in brown preadipocytes is independent of Erk1/2, PI3K and mTOR.
Exp Cell Res
; 328(1): 143-155, 2014 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-25102377
10.
The Nitrate-Nitrite-Nitric Oxide Pathway: Potential Role in Mitigating Oxidative Stress in Hypertensive Disorders of Pregnancy.
Nutrients
; 16(10)2024 May 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38794713
11.
Role of G protein-coupled receptor kinases (GRKs) in ß2 -adrenoceptor-mediated glucose uptake.
Pharmacol Res Perspect
; 12(1): e1176, 2024 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-38332691
12.
The novel adrenergic agonist ATR-127 targets skeletal muscle and brown adipose tissue to tackle diabesity and steatohepatitis.
Mol Metab
; : 101931, 2024 May 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-38796310
13.
Interaction with caveolin-1 modulates G protein coupling of mouse ß3-adrenoceptor.
J Biol Chem
; 287(24): 20674-88, 2012 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-22535965
14.
Use of Isothermal Microcalorimetry to Measure Cellular Heat Production in Thermogenic Adipocytes.
Methods Mol Biol
; 2662: 77-85, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-37076672
15.
Activity and Stability of Nanoconfined Alpha-Amylase in Mesoporous Silica.
ACS Mater Au
; 3(6): 659-668, 2023 Nov 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-38089657
16.
Mesoporous Silica Particles Retain Their Structure and Function while Passing through the Gastrointestinal Tracts of Mice and Humans.
ACS Appl Mater Interfaces
; 2023 Feb 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36731867
17.
Effect of ß2-agonist treatment on insulin-stimulated peripheral glucose disposal in healthy men in a randomised placebo-controlled trial.
Nat Commun
; 14(1): 173, 2023 01 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36635304
18.
Engineered mesoporous silica reduces long-term blood glucose, HbA1c, and improves metabolic parameters in prediabetics.
Nanomedicine (Lond)
; 17(1): 9-22, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34854740
19.
Elovl2-Ablation Leads to Mitochondrial Membrane Fatty Acid Remodeling and Reduced Efficiency in Mouse Liver Mitochondria.
Nutrients
; 14(3)2022 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-35276915
20.
Towards mesoporous silica as a pharmaceutical treatment for obesity - impact on lipid digestion and absorption.
Eur J Pharm Biopharm
; 173: 1-11, 2022 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-35134512