Detalhe da pesquisa
1.
Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7.
Cell
; 178(5): 1222-1230.e10, 2019 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-31442409
2.
Novel ß-Glucocerebrosidase Activators That Bind to a New Pocket at a Dimer Interface and Induce Dimerization.
Angew Chem Int Ed Engl
; 60(10): 5436-5442, 2021 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33238058
3.
Hapten-directed spontaneous disulfide shuffling: a universal technology for site-directed covalent coupling of payloads to antibodies.
FASEB J
; 29(5): 1763-79, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25670234
4.
A monoacylglycerol lipase inhibitor showing therapeutic efficacy in mice without central side effects or dependence.
Nat Commun
; 14(1): 8039, 2023 Dec 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-38052772
5.
Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors.
J Immunother Cancer
; 10(7)2022 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35902133
6.
Structural basis for the cyclophilin A binding affinity and immunosuppressive potency of E-ISA247 (voclosporin).
Acta Crystallogr D Biol Crystallogr
; 67(Pt 2): 119-23, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21245533
7.
Synthesis, Characterization, and in vivo Evaluation of a Novel Potent Autotaxin-Inhibitor.
Front Pharmacol
; 12: 699535, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35126098
8.
CD25-Treg-depleting antibodies preserving IL-2 signaling on effector T cells enhance effector activation and antitumor immunity.
Nat Cancer
; 1(12): 1153-1166, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33644766
9.
Variable heavy-variable light domain and Fab-arm CrossMabs with charged residue exchanges to enforce correct light chain assembly.
Protein Eng Des Sel
; 31(7-8): 289-299, 2018 07 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30169707
10.
Stepwise Evolution Improves Identification of Diverse Peptides Binding to a Protein Target.
Sci Rep
; 7(1): 12116, 2017 09 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28935886
11.
Structure of the malaria vaccine candidate antigen CyRPA and its complex with a parasite invasion inhibitory antibody.
Elife
; 62017 02 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-28195038
12.
Identification of potent and selective cathepsin S inhibitors containing different central cyclic scaffolds.
J Med Chem
; 56(23): 9789-801, 2013 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-24224654