Detalhe da pesquisa
1.
Altered Distribution of SNARE Proteins in Primary Neurons Exposed to Different Alpha-Synuclein Proteoforms.
Cell Mol Neurobiol
; 43(6): 3023-3035, 2023 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-37130995
2.
ABBV-0805, a novel antibody selective for soluble aggregated α-synuclein, prolongs lifespan and prevents buildup of α-synuclein pathology in mouse models of Parkinson's disease.
Neurobiol Dis
; 161: 105543, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34737044
3.
Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-ß aggregates.
J Neuroinflammation
; 18(1): 124, 2021 Jun 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34082772
4.
Visualization of early oligomeric α-synuclein pathology and its impact on the dopaminergic system in the (Thy-1)-h[A30P]α-syn transgenic mouse model.
J Neurosci Res
; 99(10): 2525-2539, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34292621
5.
Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson's disease brain.
J Neuroinflammation
; 17(1): 119, 2020 Apr 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32299492
6.
Gram-positive bacteria are held at a distance in the colon mucus by the lectin-like protein ZG16.
Proc Natl Acad Sci U S A
; 113(48): 13833-13838, 2016 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27849619
7.
Human Astrocytes Transfer Aggregated Alpha-Synuclein via Tunneling Nanotubes.
J Neurosci
; 37(49): 11835-11853, 2017 12 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29089438
8.
Secretion and Uptake of α-Synuclein Via Extracellular Vesicles in Cultured Cells.
Cell Mol Neurobiol
; 38(8): 1539-1550, 2018 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-30288631
9.
Extensive uptake of α-synuclein oligomers in astrocytes results in sustained intracellular deposits and mitochondrial damage.
Mol Cell Neurosci
; 82: 143-156, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28450268
10.
The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system.
Immunol Rev
; 260(1): 8-20, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24942678
11.
Alpha-synuclein oligomer-selective antibodies reduce intracellular accumulation and mitochondrial impairment in alpha-synuclein exposed astrocytes.
J Neuroinflammation
; 14(1): 241, 2017 Dec 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-29228971
12.
Cellular Uptake of α-Synuclein Oligomer-Selective Antibodies is Enhanced by the Extracellular Presence of α-Synuclein and Mediated via Fcγ Receptors.
Cell Mol Neurobiol
; 37(1): 121-131, 2017 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26961542
13.
Mapping of Surface-Exposed Epitopes of In Vitro and In Vivo Aggregated Species of Alpha-Synuclein.
Cell Mol Neurobiol
; 37(7): 1217-1226, 2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28028735
14.
Changes in secondary structure of α-synuclein during oligomerization induced by reactive aldehydes.
Biochem Biophys Res Commun
; 464(1): 336-41, 2015 Aug 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-26129771
15.
Immunotherapy targeting α-synuclein protofibrils reduced pathology in (Thy-1)-h[A30P] α-synuclein mice.
Neurobiol Dis
; 69: 134-43, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24851801
16.
Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation.
J Neurosci
; 32(34): 11750-62, 2012 Aug 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-22915117
17.
Monoclonal antibodies selective for α-synuclein oligomers/protofibrils recognize brain pathology in Lewy body disorders and α-synuclein transgenic mice with the disease-causing A30P mutation.
J Neurochem
; 126(1): 131-44, 2013 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-23363402
18.
Studies of mucus in mouse stomach, small intestine, and colon. II. Gastrointestinal mucus proteome reveals Muc2 and Muc5ac accompanied by a set of core proteins.
Am J Physiol Gastrointest Liver Physiol
; 305(5): G348-56, 2013 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23832517
19.
Studies on alpha-synuclein and islet amyloid polypeptide interaction.
Front Mol Biosci
; 10: 1080112, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36793785
20.
Composition and functional role of the mucus layers in the intestine.
Cell Mol Life Sci
; 68(22): 3635-41, 2011 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-21947475